EnhancerAtlas

The database provides annotation of enhancers in the human hg19 genome. The enhancers were predicted based on at least three independent high throughput experimental datasets (e.g. histone modification, eRNA, transcription factor binding and DHS). Currently, the database contains 2,534,123 enhancers for 76 cell lines and 29 tissues. The database allows users to (1) examine the experimental evidences for the predicted enhancers in a given genomic region; (2) compare the enhancers across different cell/tissue types; (3) identify the enhancers associated with a gene; (4) predict the genes regulated by a set of cis-regulatory elements.

Cite us: Tianshun Gao, Bing He, Sheng Liu, Heng Zhu, Kai Tan and Jiang Qian. EnhancerAtlas: a resource for enhancer annotation and analysis in 105 human cell/tissue types. Bioinformatics 2016; doi: 10.1093/bioinformatics/btw495.

Search enhancers by region:

Search enhancers by gene:

        Gene 

                                  

Compare enhancers across cells:

Compare enhancers of gene across cells:

Generate enhancer-gene network:

        Region 

                       

Predict target genes for genomic regions (e.g. peaks from ChIP-Seq):


Or


    

|

(※ Red: cancer cell line)

Blood:
CD133+ CD14+ CD19+ CD20+ CD34+ CD36+
CD4+ CD8+ GM10847 GM12878 GM12891 GM12892
GM18486 GM18505 GM18507 GM18508 GM18516 GM18522
GM18526 GM18951 GM19099 GM19141 GM19193 GM19238
GM19239 GM19240 Macrophage P493-6 th1 CMK
HL-60 Jurkat K562 Kasumi-1 ME-1 MM1S
NB4 OCI-Ly1 Raji
Brain/spinal cord:
Fetal brain Astrocyte NH-A H54 SK-N-MC SK-N-SH
U87
Colon/Intestine:
Fetal small intestine Small intestine Caco-2 HCT116 LoVo LS174T
Lung:
Fetal lung IMR90 Lung A549 H128 H2171
Breast:
HMEC MCF10A MCF-7 T47D
Skin:
BJ NHDF NHEK NHLF
Embryonic stem cell:
H1 H9 HUES64
Heart:
Fetal heart Heart Left ventricle
Kidney:
Fetal kidney HEK293 HEK293T
Uterus:
ECC-1 Hela Hela-S3
Bone:
Osteoblast U2OS
Foreskin:
Fibroblast foreskin Foreskin keratinocyte
Leg:
Fetal muscle leg HSMM
Liver:
Liver HepG2
Pancreas:
Pancreas PANC-1
Prostate:
LNCaP VCaP
Bronchia:
Bronchia epithelial
Esophagus:
Esophagus
Hymus:
Fetal thymus
Lymph:
CUTLL1
Myotube:
Myotube
Ovary:
Ovary
Pancreatic islet:
Pancreatic islet
Placenta:
Fetal placenta
Skeletal muscle:
Skeletal muscle
Spinal cord:
Fetal spinal cord
Spleen:
Spleen
Stomach:
Fetal stomach
Testis:
NT2-D1
Thymus:
Thymus
Umbilical vein:
HUVEC