EnhancerAtlas 2.0: an updated resource with typical enhancer annotation in 600 tissue/cell types across nine species

EnhancerAtlas 2.0

Tag

Content

EnhancerAtlas ID

HS187-06351

Organism

Homo sapiens

Tissue/cell

Th1

Coordinate

chr12:120448540-120454650

TF binding sites/motifs

Number: 18

JASPAR ID

Coordinate

Motif Sequence

Strand

-Log10(p-value)

FOS	MA0476.1	chr12:120451828-120451839	TGTGACTCATC	+	6.14
FOXP1	MA0481.2	chr12:120451966-120451978	GTCTGTTTACTT	-	6.52
FOXP1	MA0481.2	chr12:120451929-120451941	TTCTGTTTACTT	-	7.22
FOXP2	MA0593.1	chr12:120451930-120451941	TCTGTTTACTT	-	6.32
FOXP2	MA0593.1	chr12:120451967-120451978	TCTGTTTACTT	-	6.32
JUN(var.2)	MA0489.1	chr12:120451824-120451838	AGGATGTGACTCAT	+	6.21
JUND	MA0491.1	chr12:120451828-120451839	TGTGACTCATC	+	6.14
NFAT5	MA0606.1	chr12:120450015-120450025	ATTTTCCATT	+	6.02
NFATC1	MA0624.1	chr12:120450015-120450025	ATTTTCCATT	+	6.02
NFATC3	MA0625.1	chr12:120450015-120450025	ATTTTCCATT	+	6.02
Nr2f6(var.2)	MA0728.1	chr12:120450898-120450913	AAGGTCAGGAGTTCA	+	6.04
Nr2f6(var.2)	MA0728.1	chr12:120451780-120451795	TGACCTTTTGATCTC	-	7.6
ONECUT3	MA0757.1	chr12:120453910-120453924	TGTATTGATTTTCC	-	6
RFX1	MA0509.2	chr12:120450317-120450333	TGTTGCCATGGATACC	+	6.38
RFX1	MA0509.2	chr12:120450317-120450333	TGTTGCCATGGATACC	-	6.4
RFX2	MA0600.2	chr12:120450317-120450333	TGTTGCCATGGATACC	+	6.49
RFX2	MA0600.2	chr12:120450317-120450333	TGTTGCCATGGATACC	-	6.57
TCF7L2	MA0523.1	chr12:120449392-120449406	TTCCTTTGAAGTTA	-	6.18

dbSUPER

Number of super-enhancer constituents: 4
ID	Coordinate	Tissue/cell

SE_12162	chr12:120448448-120454060	CD3
SE_16646	chr12:120448110-120453900	CD4_Naive_Primary_8pool
SE_18355	chr12:120441816-120454766	CD4p_CD25-_Il17-_PMAstim_Th
SE_19541	chr12:120448140-120454365	CD4p_CD25-_Il17p_PMAstim_Th17

HEDD

Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder
Number of disease enhancers: 5
Chromosome	Start	End

chr12	120452790	120453543
chr12	120449586	120450829
chr12	120451355	120452441
chr12	120449080	120449668
chr12	120452367	120452606

GeneHancer

Number: 1
ID	Chromosome	Start	End

GH12I120011

chr12

120449518

120453944

Enhancer Sequence

GTTTTTTTTT ATCTGAGTTT AAAGAAAAAT GATGTGCAGT CACTAATCTA TGACTAGTTA 60
AGGAAGCAGA GCCCCGGGGA AGTTAAGTGA TTTGCTCAAG TCTGCAGTCC CAGTCCTCTG 120
CTGCTTCCTG TGGGGCTCTT ACTGGCTTAA CAAGTAAAAC AAGCCATCTC TTTGATAATA 180
AATGATATTT ACTGATTAAG AAAAAAAGGG GTGGTATTCA TTATTTGTAG AAGAGTAACC 240
CTAGTTACAG TTTTATTCGT TAATACTGAA GTTGTTGTGA CGGATCAGTC ACCAACTTTT 300
AGTAGCCTAA CAGGAATTAA AAGCTGGTAT TCCTGAGTGG TCAGTGGCTC TTAGTTCAGG 360
CAGTGATTCA GTTCTCCTCC AGCCATCTTC CATCTTGTGA CTCGGCTGTT TTCAACAGGT 420
GACTTCTAAG GTCGTAGCAG AAGGAAAAGA ACCTGGAAGA TTTCTGTGGG CTATGCCTGG 480
AAATGGTGCC TGTTGCTTCC GCTCATTTGC TGGTCAGAGC TCAGTCACAT GGCCATACTC 540
AGTTACAAGA AAACCTGGGA AATGTAGACC AGCTTTTTGC CCAGGGAGGA GAAGAAATGG 600
GTTGGTGAAC AACTAGCCAG TGTCAGCCAT AATGGAGTCA GTAGAAAGAG TCCTGGGCTT 660
CAGTTTTCTA AAGAGATTAG AGTGGCTGAT TGCTAAGATC TTCCAATTCT AACTAGGTAG 720
GATTCCAAGG CAGATATAGT TGTAACAGTA TCACCTTTTT TGGTACACAT TCACCATTCT 780
ATCCCAGATA GAGAAGCTGT TTGGTCTTTT TGTACTCAGG TAATATCTTT GATAATCACA 840
GAGTTGGGTA AATTCCTTTG AAGTTATAAC TTGATCCAGA ATCCCCAAAA TAAAAAAAAG 900
TTGGTATCTT TTTCAGGGAT TGCCTTAGGG TGAGATAGAC CCTTTCATGG TTATATTAGG 960
TAGAATAACA TTAACTGTTA TAATACATAA ACCCTAAGCT CTCAATGGCT TTACATAATA 1020
GAGGTTTTTT TCTCATTCCC ATAAAGTCCA ACAGCATTTC TGTTTAAACA TGAGGAAGAA 1080
TAGCATTGTG CTTTAATGGA ATGAATTGAC CTGGAAAACA GAAGACCTAG GTTCTAGCCC 1140
ATGTTCTGTC ACTAATTTTC TGACTTTGAA TAAATCCTCA CTCTGGGTTT CAATTTCTGT 1200
CAGTAAAACA CGGAGATTGA ACGAGATGAT TCCTTCGCTC TCTAAATGTC CACATGTACG 1260
TATGCGATCT CTGTTGGAAA GAAAATTAGT AGAGAGATAG TCTCACATGA TGTGGTATAT 1320
CATGTCTGGT AACTTTGTAA TGCTGCCGCC TTTGCATGCA GAACATATTC ATCCTTCTCT 1380
GGGACCGAGG GCGGCTTCTC CTCTCACCCA AATTTACTCC TTTGTGTAAT GAGAAATAGA 1440
GAGAGGTTGA GATGATTGGT GCCACAACAA AATTTATTTT CCATTCCAGT CATGACACAT 1500
AAGGTACTTT CCCTGCACAC GACTGACGGT GTGGGGAATG AGGAGGTGTT TATGTGATTT 1560
TCCTGTTTAA AATTATGCAT CATAGTACTA AGGTTTTATG AGGTTGACAT TCTGTAATTC 1620
TCCACGAATA AGTCAGATTT TCCGCATTGC CCTGGTATGA TTAGTTGCAT TCAATGCTGC 1680
ATGTTTGTCA TTTGCAGAAC TGTAAGAATT CCCCCTATAC ACACCTCTCG TCATCAGTTG 1740
CTAGGTTACG GCTTTTCACA TTGTCCCAGT CTGGTGATGT TGCCATGGAT ACCAGTTATA 1800
CCTCCTCCTA TGACACTGTC CTGGTCAGGC TCAGAGGGCG GGCAAGATGT AACTATGATG 1860
TCAGAGATGT TTTAGCATAT GTCTTTCCCT TTACATTAAT GATAAGATCT AAGTAATAGA 1920
TATCAATTCT ATGTGTTCTC ATATATGAAT TAAGGACATG AGGTATTAGC TGAATCCCTC 1980
AAACAGTCCA CCACTTAGAA CCTTTATTCC ATTATGTATT TTTTTTCTTT TTTAAAGGAA 2040
AGGGAAGGGA AAGGAAGGGG AAAGCCTTTA TTCCATTATA ATTCTGCAGA AATGGAACTA 2100
ACAGATTATA AAATATGAAT ATAAGATCTG CTATACTGTG TCCAGCTCAT TCCCTACACA 2160
GACCAGCACC CCACCTCCCA TAGGGTGGGC TATACATGGA ATATCATTAT CCTTTACATT 2220
GCCTTCAGTG GTAGGGACAT TTGGGAATGC TTTTTGTCAA ACTCTTAATT TATCTAAGTT 2280
ATAAAGCCTG TGGGCCGGTA ATGGTGGCTC ATGCCTGTAA TCCCAGCACT TTGGGAGGCC 2340
AAGGCGGGTG GATCACCTAA GGTCAGGAGT TCAAGACCAG CCTGGCCAAC ATGGCGAAAC 2400
CCCGTCTCTA CTAAAAATAC AAAAAAAATT AGCCGGGTCT GGTGGCATAT GCCTGTAGTC 2460
CCAGCTACTC AGAAGGCTGA GGCAGGAGAA TCGTTTGAAC CTGGGAGGTG GAGGTTGCAA 2520
TGAGCCAAGA TCACACCTCT TCACTCCAGC CTGGGGGACA GAGCAAGACT CCATCTCAAA 2580
AAAAAAAAAA AATTATAAAG CCTGTGGTCC AAATTTTATT GTCATTTAAT GTCACATGAT 2640
TATATTTCTT CTCCTGCTAG GTTTTAGACA CCATGAATTG CAGGGACTAT GTCTTTAACC 2700
AGAGTGTGTG TGTGTGTGTG TGTGTGTGTG TGTGTGTGTG TGTGTGTCAG AGTCTTACTC 2760
TATCACCCAG GCTGGAGTGC AGTGGCGCGA TCTCGGCTCA CTGCAACCTC CGCCTCCTGG 2820
GTTCAAGTGA TTCTCCTGCC TCAGCCTCCT GAGTAGCTGG GATTACAGGT GCCCGCCACC 2880
ACGCCTGGCT AATTTTTGTA TTTTTAGTAG AGACAGGGTT TTGCCATGTT GATTAGGCAG 2940
GTCTTGAACT CCTGGCCTCA AGTGATCCGC CTGCCTCAGC CTCCCGAAGT GCTGGGATTA 3000
CAGGCGTGAG CCACCGTGTC CAGCCTTTAA CCAGTTTTTA TCCCCAACAA CACTTAGTGC 3060
CATGCATATT ATGGCAGGGA TCCAGAAAAG TCTCATTGAT TTGTTCTGAA GACTGAAATG 3120
TAGGTAATAA CTAATTTGAC TTTAGATTTC TAGCATAGTG TTTTAAGATG GTGGAAACCC 3180
CCGCATATTA CAGTTGTTGA AGGGCAAGGT TAACCCATGT TATTTAGCTC TTGTCTAGTC 3240
TGACCTTTTG ATCTCACAGT TGAAGAAAGC ACTAAGGCCG TAGGAGGATG TGACTCATCT 3300
AAGGTCACAG CCAGTAAACC TGTGGTTTAG GTAAATGTGT GTTATAAAAA ATCTTTGAAA 3360
AACAAGGTGT AAAAATCTTT GCAAAGTAAT TCTGTTTACT TAAACGATCA TGTTTTGTTT 3420
TATGCAGTCT GTTTACTTAA AAACCTAGCA GACAGAAAGC TATTATTAAA GAAGAACTTC 3480
AATATTTAAA AGGAGCCCTA CATAGAACCT ACCTACCAGT TACTTCAAGT CAACTCGAAG 3540
CCTTGCATTC TGCTTAGTAT TTGAATTATT CCTCAAAAAC CAAAATAAAA TTTAATGTAG 3600
CATCGGATTG AGGCATCTTT CAAAAGTAAC ATCTATTTTG AAAACCAGCA GAGTTTGAAT 3660
TAAAAAACCA TTCTTGCACC GGTGCAGTGG CTCACGTCTG TAATCTCAGC ACTTTGGGAG 3720
GCTGAGCCGG GCAGATCACA AAGTCAGGAG ATCGAGACCA TCCTGGCCAA CATGATGAAA 3780
CCCCGTCTCT ACTGAAAATA CAAAAATTAG CCAAGTGTGG TGGCGCGTGC CTTTCATCCC 3840
AGCTACTCAG GAGGCTGAGG CAAGAGAATC GCTTGAACCC AGGAGGCAGA GGTTGCAGTG 3900
AGCCGAGATC ACGGCACTGC ACTACAGCCT GTGACAGAGC GAGACTCCAT CTCAAAAAAA 3960
AAAAAAAGCA AACCATTCTT GGCTGGGTGT GGTGGCTTAC ACCTGTAATC TCAACACTTG 4020
GGAGGCCAAG GTGGGAGGAT TGATCCCAGA AGTTCGAGAC CACCCTGGGC AACATGGTGA 4080
GACTCCCATC TCTAAAAAAA AATTAAAAAA TAAAAAAAAT TATTTGTATG TCATGTTACT 4140
TCCCTAAAAT GAAAGGAATT TATTTACCAA ATAGAATCCT TTGTTTGAAA AAAAAATGAG 4200
TGAAAACATG TCTTCTGAAA ATACAGTCTG CTAAAGTTAT AGGTTATGGA CTTTTAACTG 4260
TCAGTGGGAG AGACAGACAA ATCTTATGAG AGTCAGGGAA AGTGACAAAG CTGAAACCCT 4320
CAAGAGAGGA CACATAATTC AAGATGGATC TTCCCTCCCT TGCCCCAAGA CCAGAGAATT 4380
CAAGAGTCTG CCCCTTCCCA CTTGCAGTGG GAAGGGAAAG CTTGTTGAAG CTTTCTTAAC 4440
TTTATGCAAT AACCTGAAAC ATCTCCTTGC CTTTAAGCTC TGCTCCTCCA TTTTTTCCCA 4500
TTGTCAGATA CCTTCCTCTT TGGAAGCTCT AAACAACTCT TACTGCATTT AGGGGACTCC 4560
CTTGGCATAA CAAATAAGAA AGGGCATGGC ATTCAAAGCC CTGTACCTTC TGGACCTAGC 4620
ACACATTTCC AGCCCTGCCT CTTCTTTCTA CTTGTACCAC CGTTGGAATT TCCCCCAGTC 4680
CTGAAGGCCA GGCTCAGTTG CCACTTCCTT CATGAGAACT TTGCTGTTCT TCTCCCACCA 4740
GCTTTGATCT CTCCTACTTA CCAACTAGAG TGCTTTAGTC CCTTTCTTTT GTCATTTACA 4800
TTCTGTCATC TCTTACGGTT AATTCATGTA TTTGACTCCA TTGAGTCAAG GACTGTGCAC 4860
TCAGGGCACC TCCCCCACAG GGCTGAGCAC CTTATCTGGA AACTTCGTAT GTGTTAGAAC 4920
TAGATTCACA AGCCAGCTAA GCATATGTTA CTTAGTTCTG TGGTTCAAAT GTATAGCAAA 4980
CTTGACCATT TACTAAAAGG TTGAACCCAC CCAGAGAATT ATTTCACTTC TCTTAATATA 5040
TACTTAATCT TGCTGAATTC CTTTTCCATT GTCCAGATCA CTGGTTCCCA GTCTTTCAGT 5100
GTAAGGAACC CCCTTTTTAA AACCTAATCC AATGACCTTC TACAATATTT TGAAACAGCC 5160
TTATTGAAGT ATAATTTACA GTTTATAAAT TCACCCACTG TAAATGTATA ATTCAATTTT 5220
TAGCATATGT ACAGAGTTGT GCAGCCATCA CCATAATCCA ATTTTAGAAC ATTTCTGCTA 5280
CCCCAAAAAG TTCCCCCATA TCGTTCTGCA TTCAGTCTTC ACTCCTGTCC CCACCCGCAG 5340
CCCCAGGAAA ACACTGATCT GTTTTCTGTC TGTATTGATT TTCCTTTTCT GGATATTTCA 5400
TATAAATGGA ATCAGGCAAT ATATAGTTTT TGTGTCTGGC CTCTTTCACT TAGCATCACG 5460
TCTGTGAGGT TCACTCGTGT TATAGCACAT AATAGTTCCT TTTTTAGTAT TCCATTGTGT 5520
GAATATACTG CATTTTGTTT ATCCATAACC AGTTAATGGA GATTTGGATT GTTTCCAATT 5580
TTCAACTATT ATGAATAGTG CTGTTAGGAA CATTCATGTA CAAGTCTTTG GACTTACACT 5640
TTCATTTCTT TTGGGTAGAT ATTTAGGAGT GGAATTGCTA TATGGTATGT CTGTAACCTT 5700
TTTTTTTTTT TTTTTTTTTT TGAGACAGGG TCTCACTCTG TCACCCATGC TGGAGTACAG 5760
TGGCGTGATC ATGGCTCACT ACTCTGGTGA TTCTCCCACT TCAGTCTCCC AAGTAGCTGG 5820
GACTACAGGC ATGTGCCACC ATGCCCAGCT AATTTTTGTA TTTTTTGTAG AGACAGTTTT 5880
GCCATGTTGC CCAGGCTGAT CTTGAACTCT TGGGCTCAAG CAGTTTGTCC ATCTTAGCCT 5940
CCCAAAGTGC TAGGATTACA GGTGTGAACC ACCACACCTG TCCTGTCTGT AACTTTTTAA 6000
GAAACCGCCA AACTTATTTT CAAAGAAGCT TGTACCAGTT TATATTCCTA CCAACAATGC 6060
GTGAGAGTTC CAGTTTCTCC ACAAGAGGAC TCCTTTTTAG TATGTAAAAA 6110