| Tag | Content |
|---|
EnhancerAtlas ID | HS187-00371 |
Organism | Homo sapiens |
Tissue/cell | Th1 |
Coordinate | chr1:24834220-24835800 |
Target genes | |
TF binding sites/motifs | | TF | JASPAR ID | Coordinate | Motif Sequence | Strand | -Log10(p-value) |
| Foxo1 | MA0480.1 | chr1:24835259-24835270 | TCTTGTTTACA | + | 6.02 | | IRF1 | MA0050.2 | chr1:24834609-24834630 | AAAAAGAAAGAAAAAGTGAAA | - | 7.26 | | ZNF263 | MA0528.1 | chr1:24834995-24835016 | GGATGAGGATGTGGAGAAAGA | + | 6.18 |
|
| | Number of super-enhancer constituents: 7 | ID | Coordinate | Tissue/cell |
| SE_16094 | chr1:24832978-24835385 | CD4_Naive_Primary_7pool | | SE_17254 | chr1:24827520-24835390 | CD4p_CD225int_CD127p_Tmem | | SE_17366 | chr1:24826707-24839199 | CD4p_CD25-_CD45RAp_Naive | | SE_18454 | chr1:24829631-24839596 | CD4p_CD25-_Il17-_PMAstim_Th | | SE_19778 | chr1:24827461-24835269 | CD4p_CD25-_Il17p_PMAstim_Th17 | | SE_21833 | chr1:24827360-24835578 | CD8_Naive_7pool | | SE_22204 | chr1:24829637-24835542 | CD8_Naive_8pool |
|
| | Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder | | Number of disease enhancers: 1 | Chromosome | Start | End |
|
| | Number: 1 | ID | Chromosome | Start | End |
| GH01I024506 | chr1 | 24833128 | 24835500 |
|
Enhancer Sequence | AAGTTAAAAA CAGTTGTTGT ACCTGTGGGC CACCCAGATA GATATATTCA ATAGAAAGTG 60
AAAAATACGG CTAGGCGTGG TGGCGGCTCA CGCCTGCAAT TTGGGAGGCC AAGACGGGGG 120
GATCACCTGA CGTCAGGAGT TTGAGACCAG CCTGACCAAC ATGATGAAAC CCCATCTCTG 180
CTAAAAATAC AAAAAGTTAG CTAGGTGTGT GATGGCATGT GCCTGTAGTC CCAGCTACTC 240
GGGAGGCTGA GGCAGGAGAA TCGCTTGAAC CCTGGAGGCA GAGGTTGCCA GTGAGCCGAG 300
ATTGCGCCAG TGAGCCGAGA TCGCGCCACT GCGCCGAGAC TGCGCCACTG CACCCCAGCC 360
TGGACAAGAG TGAAACTCCG TCTCAAAAAA AAAAGAAAGA AAAAGTGAAA AATACAAGAC 420
TAGAACTCAG GATTGAGAGT GAGTCTTGGT ATATAAATTT GAATGTACCC ATATGGATGA 480
CTGATTTTCA GGGTATGTAG GCAGGAAAGA CCAACAGGTA GATCACAGGC TCTTGGGGAC 540
ATGGTACTTT TCCAAACTAC CCATCCTCTT TATTGCTCAA GGTTCTGCTC TGGCTTCCCT 600
CCCAACTTTG GTGACATTCA TCCTGTCTTA AGGTCGTTGC ACGAAATGAG AGCCAGTATT 660
GACACAGGTG TGTGTGAACC ACAGGGAGGC AGGAACTTAG TTGAGAACCT CTGGTGATTA 720
GGCAGCTAAA TACTCCAGTG TGGATAAAGT CACGCAGGAG AGAAAGATGA AAAAAGGATG 780
AGGATGTGGA GAAAGAGGCA GTAAAAAAGA TAGAGCTGGT GAGGAAGAAG GGCCAGGAAG 840
AGGCAAGACC CAGAAGGCAG GGACACAGGG AGGTCTAAGA ATGAATGGAA TAGGCAGCCA 900
GGTCATGTGC TACAGAGATA GGCTGAGACC TGACACTGGG TTTCAACTAC AGGCTTGTTC 960
GGGGATATCG CGGGTTTCGT TACAGATAAT TGTAATAAAG CCGGTCACAC GAATTTTGGT 1020
TTCCCAGTGC ATATAAAAGT CTTGTTTACA CTATACTATA GTCTATTAAG TGTGCAATAG 1080
CATATGTCTT AAAAAAATTT ATAGACCTTC ATTTAAAAAA TACTTTGTTG CTAAAAAATA 1140
CTAATGATCG GTTGGTGTGG TGGCTCACAC CTATAGTCCC AGTACTTTAG GAGGCTGAGG 1200
CGAGTGGATC ACTTGAACCC ATGAGTTTGA GACCAGCCTG GGCAACATGG CAAAACCCCA 1260
TCTCTACAAA GAATACAAAA ATTAACCGGA CATGGTGGTG TGTGCTTGTA GTTCCAGCTA 1320
CTTGGGAGGC TGAGGTGGGG GGATCACCTG AGCATGGGAA GGTCAAGGCT ACAGTGAACA 1380
TGATCACGCC ACTGCACTAG AGTCTGGGCA ACAGAGTGAG ACCCCACCCC ATCTCAAAAA 1440
ATAATGCAAA CGATTAAGTC GTAATCTTTT TGTTGGTGGA AGATCTTGCC TTGAGGTTGA 1500
TGGCTGCTGA CTGATCAGGG TGGTGATGCT GTAGTTTGGG GTGACTGTGG CAATTATTAA 1560
AATAAGACAA CAGCATTTCA 1580
|
