EnhancerAtlas 2.0: an updated resource with typical enhancer annotation in 600 tissue/cell types across nine species

EnhancerAtlas 2.0

Tag

Content

EnhancerAtlas ID

HS177-19204

Organism

Homo sapiens

Tissue/cell

SK-N-SH_RA

Coordinate

chr6:26550380-26551260

Target genes

Number: 34
Name	Ensembl ID

HIST1H4B	ENSG00000124529
HIST1H1C	ENSG00000187837
HIST1H2BC	ENSG00000180596
HIST1H2AC	ENSG00000180573
HIST1H1E	ENSG00000168298
HIST1H2BD	ENSG00000158373
HIST1H2BE	ENSG00000197697
HIST1H4D	ENSG00000188987
HIST1H1PS1	ENSG00000216331
HIST1H2AD	ENSG00000196866
HIST1H3D	ENSG00000197409
HIST1H2BF	ENSG00000197846
RP1	ENSG00000217275
HIST1H4E	ENSG00000198518
HIST1H2BG	ENSG00000187990
HIST1H2AE	ENSG00000168274
HIST1H3E	ENSG00000196966
HIST1H2APS3	ENSG00000218281
HIST1H1D	ENSG00000124575
HIST1H4F	ENSG00000198327
HIST1H2BH	ENSG00000197459
HIST1H3G	ENSG00000256018
HIST1H2BI	ENSG00000168242
HIST1H4H	ENSG00000158406
H3F3AP1	ENSG00000220875
BTN2A2	ENSG00000124508
BTN3A1	ENSG00000026950
BTN2A3P	ENSG00000124549
BTN3A3	ENSG00000111801
BTN2A1	ENSG00000112763
BTN1A1	ENSG00000124557
HCG11	ENSG00000228223
CTA	ENSG00000261353
HMGN4	ENSG00000182952

TF binding sites/motifs

Number: 1

JASPAR ID

Coordinate

Motif Sequence

Strand

-Log10(p-value)

KLF5

MA0599.1

chr6:26550823-26550833

GCCCCGCCCC

6.02

dbSUPER

Number of super-enhancer constituents: 5
ID	Coordinate	Tissue/cell

SE_30005	chr6:26550514-26551441	Fetal_Muscle
SE_35175	chr6:26550328-26551599	HeLa
SE_59570	chr6:26550253-26578074	Ly3
SE_61702	chr6:26532165-26578026	Toledo
SE_63024	chr6:26532079-26573171	Tonsil

HEDD

Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder
Number of disease enhancers: 2
Chromosome	Start	End

chr6	26550418	26550804
chr6	26550906	26551000

GeneHancer

Number: 1
ID	Chromosome	Start	End

GH06I026549

chr6

26550084

26551428

Enhancer Sequence

TAAAGCAAAA TTTGGAATGC CTTTGTTCTC CAGATATGGG GACATCTAGA CACTCCCAAG 60
TCTGGGTCTG TTTAGTAAAC ATTATTAATT TGTTCCCTTA ACCATAAACA TCTAGAGGCT 120
AGGAATGCCT GACTTTCTGG GAATGCAGCC CAGCAAAAGT CCCGGCCTCG TTTTCCTAGC 180
CCTCACTCAA AATGGAGTCG CTCTGGTTCG AATGCCTCTC ACAGAAATCC CGCTAAAATG 240
TACCTCCCTC GGTTGCGGTG AGCCGTGATC GTGCCACTGC ACTCCAGCCT GGGAGATAGA 300
GTGAGAACTC CGTCTCAAAA AAAAAAAAAA AAAATACCTC CTTCTTCTCT CAAAACTCTC 360
CAATGGCTTC CACCCTGGGT CATCAACATG GCCTGGAAGA GCCGTACTCT GGATACCCGA 420
GGGCGCGGCC CCAGCGCCGC GACGCCCCGC CCCTCTGGCT GCTCCGCTCT GGGATGCACT 480
TCCGACGCCC TCTAGGCTTG GGAGTTCCGC GCCTCTCGGT GTCGCCTGGG GGGCGTGCTC 540
CGGTTGGCGC ACTGATTCCC AGTTGGGTAG GGGAGGCTTG ACTGAGCTCC CACCCGGAAT 600
TTCACCTTAG ACCTTTAAAG ACCTTGCTCC GGCCTCCCGC GCCAGCGCTA ACACCTAGTC 660
CTCTTTAGTG GAGTTCCGGC GGAAGGGGAT GGCGGGCACC CGACGGTGGT CTCCTCCCAG 720
ATGGCGAATT TCCGCGGCTT CTTCATCTTT TAGCTCCCAG GGAGCCCTCT GGCCCCAGCA 780
TGAAGCCCAT GGAGCCCTTT TCAAAATTGT ATTTTTAAAA GCTTTTAAAA AATACACAGG 840
ATTTTAAAGA AAGCCAATTG TACTACAAAA CAGTTTTCAA 880