| Tag | Content |
|---|
EnhancerAtlas ID | HS149-00677 |
Organism | Homo sapiens |
Tissue/cell | NKC |
Coordinate | chr2:43384280-43389990 |
Target genes | |
SNPs | | Number: 1 | ID | Chromosome | Position | Genome Version |
|
TF binding sites/motifs | | TF | JASPAR ID | Coordinate | Motif Sequence | Strand | -Log10(p-value) |
| IRF1 | MA0050.2 | chr2:43384494-43384515 | AAAGAAAAAGAAAAAGTAATA | - | 6.47 | | KLF14 | MA0740.1 | chr2:43388835-43388849 | TAGGGGGCGTGGCT | - | 6.65 | | KLF16 | MA0741.1 | chr2:43388837-43388848 | GGGGGCGTGGC | - | 6.62 | | RREB1 | MA0073.1 | chr2:43387824-43387844 | TGTGTGTGTGTGTGTGGTGG | - | 6.41 | | SP1 | MA0079.4 | chr2:43388836-43388851 | AGGGGGCGTGGCTCA | - | 6.24 | | SP3 | MA0746.2 | chr2:43388836-43388849 | AGGGGGCGTGGCT | - | 6.46 | | SP4 | MA0685.1 | chr2:43388834-43388851 | GTAGGGGGCGTGGCTCA | - | 6.34 | | SP8 | MA0747.1 | chr2:43388836-43388848 | AGGGGGCGTGGC | - | 6.92 | | Stat6 | MA0520.1 | chr2:43387619-43387634 | AGTTCCCAGGAAAAG | - | 6.41 | | TCF7L2 | MA0523.1 | chr2:43384789-43384803 | AAAGTTCAAAGGCA | + | 6.63 | | ZNF263 | MA0528.1 | chr2:43387224-43387245 | CCCTCCTACTCACCCACCTCC | - | 6.02 | | ZNF263 | MA0528.1 | chr2:43384747-43384768 | CTTCCCTGCCACCCCTGCTCC | - | 6.12 | | ZNF263 | MA0528.1 | chr2:43385486-43385507 | CCCTTCAGCTCCTCCTCCTCA | - | 6.59 | | ZNF263 | MA0528.1 | chr2:43387208-43387229 | TCCTCCTTTTTCTCCTCCCTC | - | 7.66 | | ZNF263 | MA0528.1 | chr2:43387205-43387226 | CCCTCCTCCTTTTTCTCCTCC | - | 8.51 |
|
| | Number of super-enhancer constituents: 54 | ID | Coordinate | Tissue/cell |
| SE_03102 | chr2:43384671-43387327 | Bladder | | SE_09287 | chr2:43383934-43388379 | CD14 | | SE_10736 | chr2:43385270-43387369 | CD19_Primary | | SE_11722 | chr2:43384536-43388438 | CD20 | | SE_11879 | chr2:43384841-43388354 | CD3 | | SE_11879 | chr2:43388729-43389606 | CD3 | | SE_14384 | chr2:43384968-43390226 | CD4_Memory_Primary_7pool | | SE_16107 | chr2:43385039-43388515 | CD4_Naive_Primary_7pool | | SE_16655 | chr2:43385030-43387619 | CD4_Naive_Primary_8pool | | SE_16950 | chr2:43385153-43387343 | CD4p_CD225int_CD127p_Tmem | | SE_16950 | chr2:43387407-43388460 | CD4p_CD225int_CD127p_Tmem | | SE_17323 | chr2:43384367-43390308 | CD4p_CD25-_CD45RAp_Naive | | SE_17875 | chr2:43384151-43389961 | CD4p_CD25-_CD45ROp_Memory | | SE_18565 | chr2:43384470-43389555 | CD4p_CD25-_Il17-_PMAstim_Th | | SE_19552 | chr2:43384838-43388407 | CD4p_CD25-_Il17p_PMAstim_Th17 | | SE_20209 | chr2:43384383-43388430 | CD56 | | SE_20901 | chr2:43385124-43387775 | CD8_Memory_7pool | | SE_22349 | chr2:43384494-43388457 | CD8_primiary | | SE_22349 | chr2:43388476-43389649 | CD8_primiary | | SE_23059 | chr2:43384055-43387389 | Colon_Crypt_1 | | SE_23059 | chr2:43387454-43393361 | Colon_Crypt_1 | | SE_23724 | chr2:43384477-43387342 | Colon_Crypt_2 | | SE_23724 | chr2:43387484-43388382 | Colon_Crypt_2 | | SE_23724 | chr2:43388946-43391165 | Colon_Crypt_2 | | SE_24685 | chr2:43384340-43387340 | Colon_Crypt_3 | | SE_24685 | chr2:43387443-43392842 | Colon_Crypt_3 | | SE_25333 | chr2:43383856-43391948 | DND41 | | SE_26374 | chr2:43384543-43388739 | Duodenum_Smooth_Muscle | | SE_26374 | chr2:43388866-43391613 | Duodenum_Smooth_Muscle | | SE_26557 | chr2:43384020-43387372 | Esophagus | | SE_26557 | chr2:43387438-43388387 | Esophagus | | SE_27617 | chr2:43384083-43393474 | Fetal_Intestine | | SE_28536 | chr2:43383866-43393674 | Fetal_Intestine_Large | | SE_30898 | chr2:43384773-43387387 | Fetal_Thymus | | SE_31392 | chr2:43384365-43391297 | Gastric | | SE_34919 | chr2:43383855-43388500 | HeLa | | SE_38828 | chr2:43385030-43386643 | HUVEC | | SE_43203 | chr2:43384366-43387389 | Lung | | SE_43203 | chr2:43387453-43388362 | Lung | | SE_47826 | chr2:43384619-43386674 | Pancreas | | SE_49954 | chr2:43384504-43386643 | RPMI-8402 | | SE_50052 | chr2:43384264-43393423 | Sigmoid_Colon | | SE_52337 | chr2:43383845-43392633 | Small_Intestine | | SE_53288 | chr2:43384755-43387396 | Spleen | | SE_55101 | chr2:43384949-43387332 | Thymus | | SE_56731 | chr2:43384774-43386703 | VACO_400 | | SE_56731 | chr2:43386712-43387326 | VACO_400 | | SE_56731 | chr2:43387453-43388362 | VACO_400 | | SE_56731 | chr2:43388958-43390124 | VACO_400 | | SE_58412 | chr2:43352450-43425007 | Ly1 | | SE_61450 | chr2:43354337-43468354 | Toledo | | SE_62203 | chr2:43354169-43468733 | Tonsil | | SE_65350 | chr2:43384329-43388234 | Pancreatic_islets | | SE_65350 | chr2:43388765-43389970 | Pancreatic_islets |
|
| | Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder | | Number of disease enhancers: 4 | Chromosome | Start | End |
| chr2 | 43387000 | 43388399 | | chr2 | 43388800 | 43389000 | | chr2 | 43385477 | 43386677 | | chr2 | 43385938 | 43386506 |
|
| | Number: 1 | ID | Chromosome | Start | End |
| GH02I043156 | chr2 | 43383741 | 43393336 |
|
Enhancer Sequence | CACTGTGGGA GGCCAAGGTG GGAGCATCAC TTGAGGCCAG AAGTTTGAGA CCAGCCTGGG 60
CAACATGGTG AGATTCCCAT CTCTACAGAA AATTCATGCC TGTGGTCCCA GCTGAGGTGG 120
GAGAATCACT TGAGCCCAGG AGGTTGAGGC TGCAGTGAGC TGTGTTCGCA CCACTGCACT 180
CCAGCTGGGT GACAGAGTGA GACCCTGTCT CAAAAAAGAA AAAGAAAAAG TAATATTACT 240
TGCACCAGGC AGCCTTTGGC ATTAGGGGCA TGGACATGTG ACATTCCAGG TCCCTTCCAG 300
CCCTGTGTCT CACTCGCGCG CACACTCCTA CCTGCCTCAT CCTGATGTTG CCCATTGCAT 360
CCCTGTGACC TCCCGGTTCC TCCACAGCCA GGCATTGGCT CGTGGGAACT CGGTGCTCTC 420
GGGTTTGGGT CCCAGTAGAT TCTGGAACAT CCCACCCCAC GCCTGTCCTT CCCTGCCACC 480
CCTGCTCCGC CCCAGGCCAG CATTCCTGGA AAGTTCAAAG GCACTTGGTT CAGGGGAGAT 540
GTTTCCACAC AGCTTCTGTA GCTGGAACTG GGCTAGGCAG AGAGGGGGCC CACCCACAGC 600
CCCACAGGGA CTGCATCTTG AGACCAGAAA ACTTGGAGTG GCCCTGGGGG AGCAGTGCTG 660
TTCCCATTCT CTGTGGCAGG GGCCTTGGCA GGTGCAAGAC CCAGAGTGTC CCCCCACAAC 720
CTGAGGGGGC TGCTTCTGGA CACAGAGAGC TCAGGCCTCA AATGCATCTT TTCACTAGCC 780
TTCCTGGGTC CTGCCCATTC CTAGAGACGG AGTTCACTAT GCTCCTAGCC ATGTGCTGGG 840
TGCGGGGCGA GCCCCAGATG GCTCATCGCC ACGAGGTGCA GGCACAGCCT CTCCATGAGC 900
CATCAGGAAC TCGGGGTTGC ATCAAATCCC CAAAGACTTT ACTGGGCCCA CGCTAGGCAT 960
CAGCCTGGGA TTCTCCTCCC AGGTCTCCAC CAGCTGCTGA GCACAGCGGA GGTGGGGAGG 1020
CAAGAGCATG TCCTATCCTG CCTCCTGGCC CCCAGCCCCA GTAACACAGA ACTAGGGTGC 1080
CTATTGTTTC AATGGCAGAA ATCCCCCTCC CCTCCGACCC CTGCCCCCTG CAGCACTGCT 1140
CCCCATCACT GGGCTAAACG AATGACCCGC CACTCAGCAG GTGACGACTT ACTCCTCCTT 1200
GGCCGGCCCT TCAGCTCCTC CTCCTCACCC ATCCTGACTC AGAGGCCTGT CAGCTGCCAC 1260
TGCCCCCGAG GCCTGGCAGA TTTGGGTGGG AAGGAGCTAT CTGGGTGCCA GGACCTGAGG 1320
GGCTGGCCAT GCCCTCACTC CTTACTGACC TGACCTTTAG CAGGGCCTCT GAGCATTCTC 1380
TGATCTAGAA ATGCCACATG TACACGCATG TGTGTGCACA CACACACAAA CACCCACACA 1440
CTCACACCCA GCCGCTCTAT GACCTGATGA AACAGTCTGG GTGCAGGGCT GAGGCAGGCC 1500
AGGGAGGAGA GTTAGACTGA GCAAAAGCAG GATGTGTGTG GAGCAGCCTC CTGGCCTCTC 1560
TCCCGCAGAG GCACTTCCTG GTACTGGAGG GCAAAGCGGC CCGGGGTTGG GAAAGAGACC 1620
GGTGCTGCTT GCTCCCTCTC CAGAACAGGC ATTAATTCTG GCTGCCCCTT GGTATTGGCC 1680
TCCAACTTTA TAGTTCTCTC CCTTTCTTTC TCTCTCTCTC TCCTACACAC ACCCCTCTAG 1740
ACTCCTCCCC TGCACCTCCT CAAAATTTCT CACCCACCCT CACCCCACAG AAGGAGCATC 1800
AAAGCCCCAC ATAGCCTCTG GCCTCTCTCA ACACCTAGGA GTTGAGATCA GGCCCTTGTG 1860
GCCCAGTCTT GGGGACTTCC CCCTACCAGG GTTGGCCCTC TTGGGTCCAC GCCTCTTTGG 1920
CTAGACTTCT GATCGCTCTG GCGGCCACTC CGCAGTTTCA CCACGCCTGC TCCTGCCTGC 1980
AACACACAGA AGTTGGCAGT GACTCTGCAC TGCTCCCAGC ACCCCGGATG GCTCAGGGCT 2040
GTGGCATTTT GTTTTCTTTC GTTTTTCGCC TTCATGTCTG TGCTGTTCAC TGTGCCTGAA 2100
ATCCCCTCCC CGCTAACCCT CCTGCCCATA GCGTCAGTGG CCCACATGTC AGCACCCAGC 2160
ACTTACCACT AGCGAGGCTG TGTCCTATCC TCCTGACCAT GCCAATGAAA AAAGTCCCAT 2220
TAATTATACC CACTGTTGGC CGGGTGCGAT GGCTCTCACC TGTAATCCCA GCACTTTGGG 2280
AGGCCGAGGC AGAAGGATCA CTTGAGCTCA GGAGTTCAAG ACCAGCCTGG GCAACATGGC 2340
AAGCCCCATC TCTACAAACA ATGCAAAAAT TAGCCGGGTG TGGTGGCGTG CACCTGTAGT 2400
CCCAGTCCCA GCTACTTGGG AGGCTGAGGT GGGAGGATCA CTGGAGCCCT GGAGGTGGAG 2460
GTTGCTGTGA GCTGAGATCA CGCCACTGCA CTCCAGCCTG GGCAACTGAG GGACCTTGTC 2520
TCAAAAAAAA AAAAAAAAAA AAGATACCAT TGTTCAGAGG AGGAAGCTGA GCTGACAGAG 2580
GTCAAGGAAG ATGCATTTCT ACCCAGCTTT CAAGATTCAC TTTGGACATC ACCTTCCTCA 2640
GACTCTGCCT TCTCCTCTTC ACCGCCCCAC TACGCCCCAG GCAGGAGAAA CTGCTCCCAG 2700
CCTAGAGCCA CTGCCCGTTG TAGTGACTTC TGTTTGAGGC TGAGACCTCA GCCCCCAGGT 2760
CCTGATTTGT GCCCTCCTCC CTCAGTTTTG GGGCCTGTGA GAGTGGGTGG CTGGGCCTGG 2820
GGCTGAGTCA CTGCCTAGCC TTGCCTGCCC AGCCCCGAAC CAGGCAAGCC TCGGTGCAGG 2880
TGACCCTGCT GCCCAGAGAA GTGGGCGGCA GGAAGAATGG TCAGGCCCTC CTCCTTTTTC 2940
TCCTCCCTCC TACTCACCCA CCTCCTGGCC ACTTTCCTCC CTTTTTTTTC TTTTTTTGAG 3000
ATGGAGTCTC ACTCTGTCGC CCACACTGCA GTGCAGTGGC ACAATCTTGG CTCACTGCAA 3060
CCTCTGCCTC CCAGGTTCAA GTGATTCTCC TGCCTCAGCC TCCCGAGTAG CTGGGACTAC 3120
AGGCATGTGC CACCATGCCC AGCTAAATTT TTGTATTTTT AGTACAGACG GGGTTACACC 3180
GTGTTAGCCA GGATGGTCTC GATCTCCTGA CCTCGTGATC CACCCGCCTC AGCCTCCCAA 3240
AGTGCTGGGG TTACATGGTT AAGCCACCGC TCCCGGCCCC TCCCTGTCTT TTCACACCCA 3300
CTTCTCTCTC TGCCCAACCC TGTCTACACC CTTCCTGCCA GTTCCCAGGA AAAGTGACTT 3360
GGACTTTGCT GATGGGAAGC AGAATCTGGG CTAAAACTAG GACAGGAGCA GGGCTGGTTC 3420
CTCCAGCAAC TCCCCCAGCT CGAAGGAGGC CCAGCCTGAA CCACATCGCC AGGAGCCCTG 3480
GCTCAGCACT GGGGGTTACC TATGGGCGGC CACTTCAACT TGTGTGTGTG TGTGTGTGTG 3540
TGTGTGTGTG TGTGTGTGTG GTGGGCAGGG CGGGGGAGAT GTATATTGAT GAGGGAGGGG 3600
AAATGGACCA TTGGGCCCCA GCTTCAACGC CACATTTATT TACTGGGCAC TGAGTTAAAA 3660
ATAGACCTGA GTGCCCCTAG TGCAGGCTGC AGATAGGGAG AGGGATTCCA GGACCCCTGG 3720
GAACTAGCTA TGTCTCAGGG CCTCCACATG ACCTCCCTCT CCCTGAGGGG TGGATCTGTG 3780
ATTCTGCCGA GTGTCACACA CACCCCTGTG TTACTGGGTG GCACCAGGGC AATGTTTTGT 3840
GCACTTCACA GATTACAGTG TTGTGTCGCA GAAGAGCATG GACTTTAAAC CTAGACGGGA 3900
TCCCAGCAAG GGATGACTGC ACACCTGCCC CACTTCTGGC CTCCATTTTA CAGAGAGGGA 3960
GACTGCGGCT TAGGGACAAA TGACCAGCTC AAGGGCATGC AGAACCAGGC TGGACTCGGG 4020
TTCCTTGGCT CCCAATTCTG GACTTTTTTT TTTGAGACGG AGTCTCGCTC TGTCGCCCAG 4080
GCTGGAGTGC AGTAGCGTGA CCTCGGCTCA CTGTAACCTC CGCCTCCCGG GTTCAAGCGA 4140
TTCTGCTGCC TCAGCCTCCC GATTAGCTGG GACTACAGGT GCCCGCCACC ACGCCTGGCT 4200
AATTTTTGTA TTTTTAGTAG ACACCTGGTT TCACCGTGTT GGTCAGGCTG GTCTCGAACT 4260
CCTGACCTCA TGTGATCCGC CTGCCTCCGC CTCCCAAAGT GCTGGGATTA CAGGCATGAG 4320
CCACCACACC TGGCCCCAAG TCAGGACTCT TTCCACTGTG TTATATGGCA CCCATCACAT 4380
TGGATTCTGT TTTATTCCAT CTTGTTTCAT GTTATGTTAT ATAATGCAGG CAGAGGGGTG 4440
GGAGGTAGCG GTTGGAGGTG GAAAAGTGGC CAGAAGGTGA CAAAAAAGCA ATAGGCTAAG 4500
GTCCAGGCAA TGAGCCCACA TCTTCCCCCA CCTGAGATTT CTCCTCCATC AGGTGTAGGG 4560
GGCGTGGCTC ACCCCGGCAC CCAGTGCCCT AATTAGCTCC TGTTGACAGT TTCTGGTTTA 4620
TGTGTTATCA CCTTGAGCCT GCTTATCTTT ATCAGAGCCA AAGGTTGATT GGGGCATTCT 4680
GGCCAAAGCT CAAAGCAACT CCACTCCAAT TTCACAGGGC ATTTATGACT ACTGTGAATA 4740
ATAACCCTCT TTCCTCAAGA TAGCAGCCTG ATCCATTCAG GACCTTCCCT GCAGAGTCCT 4800
TGGTGTGATC CTTACCATCC TCACCAGGAA GACAGCACAG AGTCCTTCTC CCATTGGCTG 4860
GGGAGAAAAG CGATGCACAG CCCCAGGGTG AGCTGGCCGG GGACCCAGGT CTCCTGAGCC 4920
CTGTCCTCAG CACCCAGCAG CAATGCCCCG GCTCTGGAAC CTGACAAAGT GAGACCTCCC 4980
TACCAGGGCC ATGGCCCCCG CTTCTCCAGC CTCGCTCGCC GGGACAAAGG TTACGGGCCT 5040
TATCAACCAA GGAGGTAGAA TATTAATCTG GCCATCTATG CCCCAGCCCT GACCCGCATA 5100
GCAAAGCCGC CATCATCCAG GTGGTGGGAG TATCTGTGCA TCGGGACAGA ATGAGGTGGG 5160
GCTATGTAAG GGGCCCCCAT GAGGGCAGGG CCCTGCACAT GGCCTTTGTG GCCGCTGGAG 5220
GGGCTCACCC TAGGTCTTTT CCCACATCAG CCTTGGAGCC ACGACCTCAG GTTCTCACCA 5280
GCTCCCCTCT GAGCCCCAGG AGAGATATCT TGTCTGAGAA GTGACCCAAA CCCTTCCTGA 5340
CCCCTGATAT TCCTACTTGG ACCCCCTTGG GGGCAGTGGC CAGAGGGTTT GTCACTGTCA 5400
GAGCAGACCT GGGTCCTACT CCCAGCTCTG CCATCATCTC CATCCTTGGT ACCCGGGGCA 5460
AGCCACAGCA CGCACAGACC TCAGCTGCAT CACCGGTAAA ATGGGAGTAG ACTTTGATCT 5520
GTCCCAGAAT ACCCTCCTTC CCTGGAGATG TGGTACCTGA GTCTGGGTGG CGACCCCTCC 5580
CCATCTGCAT AGATACACCT GGAACAGGAT CCAGGCCCCT GGATGTCACT CTTTTGTGTT 5640
TTACACTTCA CTGGCCTCAC TTATGGCCAC CTAAACCCCT TAGCTCCTGG GCCAAGTCTT 5700
CAGGGACTCC 5710
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