EnhancerAtlas 2.0: an updated resource with typical enhancer annotation in 600 tissue/cell types across nine species

EnhancerAtlas 2.0

Tag

Content

EnhancerAtlas ID

HS133-13658

Organism

Homo sapiens

Tissue/cell

melanoma

Coordinate

chr17:78785110-78785940

Target genes

Number: 24
Name	Ensembl ID

CTD	ENSG00000262172
CCDC40	ENSG00000141519
SLC26A11	ENSG00000181045
SGSH	ENSG00000181523
RNF213	ENSG00000173821
ENDOV	ENSG00000173818
NPTX1	ENSG00000171246
RPL32P31	ENSG00000213128
RPTOR	ENSG00000141564
RPL31P7	ENSG00000232083
RP11	ENSG00000262833
CHMP6	ENSG00000176108
AC127496.1	ENSG00000175911
BAIAP2	ENSG00000175866
AATK	ENSG00000181409
AZI1	ENSG00000141577
AC027601.1	ENSG00000260005
C17orf56	ENSG00000167302
C17orf89	ENSG00000224877
SLC38A10	ENSG00000157637
BAHCC1	ENSG00000171282
PDE6G	ENSG00000185527
C17orf90	ENSG00000204237
RP13	ENSG00000262049

TF binding sites/motifs

Number: 5

JASPAR ID

Coordinate

Motif Sequence

Strand

-Log10(p-value)

KLF4	MA0039.3	chr17:78785574-78785585	CCACACCCTCT	+	6.02
KLF4	MA0039.3	chr17:78785824-78785835	CCACACCCTCT	+	6.02
Klf1	MA0493.1	chr17:78785822-78785833	AGCCACACCCT	+	6.02
SP1	MA0079.4	chr17:78785374-78785389	ATAGCCACGCCCTCT	+	6.01
SP4	MA0685.1	chr17:78785374-78785391	ATAGCCACGCCCTCTCC	+	6.17

dbSUPER

Number of super-enhancer constituents: 2
ID	Coordinate	Tissue/cell

SE_18550	chr17:78784696-78787241	CD4p_CD25-_Il17-_PMAstim_Th
SE_61329	chr17:78746647-78820938	HBL1

HEDD

Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder
Number of disease enhancers: 1
Chromosome	Start	End

chr17

78785735

78785852

GeneHancer

Number: 1
ID	Chromosome	Start	End

GH17I080811

chr17

78785261

78785410

Enhancer Sequence

TCAGCGGCTT CCTCTGTGTC TGTGGAGGGG ATCGTACAGC TGTTCACCCT GTTCAGATGG 60
TGCATCACAT GAATGATGTT CAGATGTTAA ACAGTCTTGC ATCCCTGTGG TAAACCCCAG 120
CTGGTCATGG TATATTACCC TTGGATAGAT TGCGGGATTT TACTTGCATT TCATTGAAGA 180
TCATCTCACA TGTGTTCTTC TCTACCTGTG GGAGACAGCC ACGCCCTCTC CAACAAGGCC 240
TAAACCTCAC TCTATCCACA GAACATAGCC ACGCCCTCTC CAACAAGGCC TAAACCTCAC 300
TGTACCCACG GGACACAGCC ACGCCCTCTC CAACAAGGCC TCAACCTCAC TGTACCCACG 360
GGACACAGCC ACGCCCTCTC CAACAAGGCC TAAACCTCAC TCTACCCAAG GGACACCGCC 420
TCTCTCCAAC AAGGCCTCAA CCTCACTCTA CCCAAGGGAC ACAACCACAC CCTCTCTAAC 480
AAGGCCTAAA CCTCACTCCA CCGGTGGGAC ACAGCCACAG CCTCTCCAAC AAGGCCTCAA 540
CCTCACTGTA CCCACGGGAC ACAGCCACGC CCTCTCCAAC AAGGCCTCAA CCTCACTGTA 600
CCCACAGGAC ACAGCCACGC CCTCTCCAAC AAGGCTTAAA CCTCACTCCA CCCGTGGGAC 660
ACAGCCACAG CCTCTTTAAC AAGGCCTCGA CCTCACTGTA CCCACGGGAC ACAGCCACAC 720
CCTCTCGAAC AAGGCCTCAA CCTCAGCCCT ACCTGGGGCC TCCTCCAGGT GCTGGGATTA 780
CAGGCATGAG CCACTGTGCC CAGCCCTTGA TTTCTTAATA TACTAAATTT 830