| Tag | Content |
|---|
EnhancerAtlas ID | HS133-07253 |
Organism | Homo sapiens |
Tissue/cell | melanoma |
Coordinate | chr12:28175660-28184770 |
Target genes | |
TF binding sites/motifs | | TF | JASPAR ID | Coordinate | Motif Sequence | Strand | -Log10(p-value) |
| Arid3b | MA0601.1 | chr12:28180731-28180742 | TTAATTAATAT | - | 6.62 | | ELK1 | MA0028.2 | chr12:28179833-28179843 | ACCGGAAGTG | + | 6.02 | | ELK4 | MA0076.2 | chr12:28179833-28179844 | ACCGGAAGTGG | - | 6.32 | | ERG | MA0474.2 | chr12:28179833-28179843 | ACCGGAAGTG | + | 6.02 | | ETS1 | MA0098.3 | chr12:28179833-28179843 | ACCGGAAGTG | + | 6.02 | | FEV | MA0156.2 | chr12:28179833-28179843 | ACCGGAAGTG | + | 6.02 | | FLI1 | MA0475.2 | chr12:28179833-28179843 | ACCGGAAGTG | + | 6.02 | | Gabpa | MA0062.2 | chr12:28179834-28179845 | CCGGAAGTGGC | + | 6.62 | | MEF2C | MA0497.1 | chr12:28177621-28177636 | AGCTATTTTTAAATC | - | 6.03 | | NFIA | MA0670.1 | chr12:28181064-28181074 | GGTGCCAAGT | + | 6.02 | | POU6F1 | MA0628.1 | chr12:28180730-28180740 | ATTAATTAAT | + | 6.02 | | POU6F1 | MA0628.1 | chr12:28180730-28180740 | ATTAATTAAT | - | 6.02 | | RUNX1 | MA0002.2 | chr12:28179797-28179808 | AAACCACAGAA | - | 6.32 | | STAT3 | MA0144.2 | chr12:28180382-28180393 | TTTCCCAGAAG | - | 6.62 | | ZBTB7A | MA0750.2 | chr12:28179832-28179845 | CACCGGAAGTGGC | + | 6.17 | | ZEB1 | MA0103.3 | chr12:28178514-28178525 | GGGCAGGTGCG | - | 6.02 |
|
| | Number of super-enhancer constituents: 4 | ID | Coordinate | Tissue/cell |
| SE_36031 | chr12:28173763-28178615 | HMEC | | SE_36031 | chr12:28178649-28181419 | HMEC | | SE_64361 | chr12:28173510-28178080 | NHEK | | SE_64361 | chr12:28178690-28181537 | NHEK |
|
| | Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder | | Number of disease enhancers: 3 | Chromosome | Start | End |
| chr12 | 28176067 | 28176342 | | chr12 | 28176169 | 28177303 | | chr12 | 28179755 | 28179885 |
|
| | Number: 1 | ID | Chromosome | Start | End |
| GH12I028021 | chr12 | 28174144 | 28181562 |
|
Enhancer Sequence | ATGTTAAACA TCTAGTCCAG TTTCAGACAC ATAATAAAGA CATTGTGGAT GCGGGTTACT 60
CTTTGTTTCT ATAACTATTA CCCCATTAGT TAGCTATTGC TGCAGAACAG ATTACCCCAA 120
AACTTGGTGG CTTAAAACAA CTAACATTTA TTTTCTTAGT TTCTGTGGAT CAGAAACCTG 180
GATGCAGATT ATTTGGGTGC CTGTGTGTAT TAGTCTGTTC TTGCATTGCT ATAAAGAAAT 240
TTCTGAGACT GGGTCATTTA TAAGAAGATA GGTTTAATTG GCTCATAGTT CCATAGGCTG 300
TACAAAAAGC CTAACACTGG CATCTACTTC TGGGGAGGCC TCTGAAAGCT TACAATCGTG 360
GCAGAAGGCA AAGCTGGAGC TTGCACGTCA CCTGGGGAAA GCAGGAGCAA GAGAGTGGGA 420
GGGGAGGTGC CACACACTTT TAAATGACCA GATGTCATGA GAACACACTC ACTATCATGA 480
GGACAGCACC AAGGGGATGG CGTTAAATCA TTCATGAGAA ATCTGCCCCA TGATCCAATC 540
ACATCCCACC AGGCCCCACC TCCAACACTG GGGATTACAT TTCAATATGA GATTTGGGTG 600
GGGACACACA TCCAAACTCT ATCACTGTGA CTCAGGGTTT CTCACAAGGC TTCAACTAAG 660
ATATTCAACA GGGCTGCAGT CATCTTAGAG TTCAACTGGG GAGGATACAC TTCCAAGCTC 720
GCTCAAGTGA CTGTTGGCAG GCATCAGGCC CTTGCTGCTG TTGACCGGAG ACATCAGTTC 780
CTTGCCACAT GGGCCCCTCT GTAGGGCAGC TCACAACAGG GCAGCTCACA ACATGGCAGC 840
TCACTTCCCT CAGAACAAGC CAGTGGGAGA GTGAGAGGGG AGGCCAAAGC CAGAAGCCAC 900
AGATTTTTTT GCCCTCTAAT GTCGGAAGTG ACAGCTCATC ATTTTCGACT TATTCTGTTC 960
ATTAGAAGTG AGTCACTAGG TCCAGCTCAT GCTCAAAACC AGGAAATTAC ACAAAGGCAT 1020
GAATACCAGG AGGTGGAGAT CACTGTGGGG GGTAGGGGAG GTGCATTTTA GAGGCCACCT 1080
GGGAAAAATG GGGCTGTAGC TTATTTACTA ATGTTTGTGT TTTTATATTT TCAATGTTTG 1140
ACATAGTATC TGGCTCAACA CAATCTTACC CCTATGGCTA AGATTTTCTT CGTTCTGGGA 1200
AATATGAGAG ATTCCTCATT GTCAGTTGCC CACATAGCAT TGATTTCATT GCTCTATTTT 1260
AAGGGAACAG CAATTACCAA GGCAAGACAC CATGAAAGGT GGAAGAATGT AGCCTGCAGC 1320
CTGTCCCACC GTTTGGGACA GGTGGGATGG ACTGCCGGAT AGCGTGTAGG AAGAAGATTA 1380
AAACAAATGG GGGAAATTTA CACACATCAT TTATTTATCT AAAATGTTCT CCCTGTCATA 1440
GTCTATTCCC TCTTTAAACT GTGGAAAGAA AAGCCCTAGC ATAAACTTGG TGTACCTTTT 1500
AAAAATTATT ACCTGGTACT TCATTTAAAA GAAAAGGAGA AATTATAATT AACCAGTTAA 1560
GACTCACCTT TTCTGACATA GCATGTGGTT GTATACATCT GGTTGTAACC ATGGTTCAAG 1620
TTGATCAACC ACCTACCAGT TGGCTAAATA AATTCCTGAT ATGCTAGGCA TCTGGGATGA 1680
ACTTCCCTCA GACAAGCCTT TAGCTCATGG CTCATAAGAA TGAATCTTGT TTTGTATGAT 1740
GTCATTGAGT GTGGAGATAT GCTGATGGAA AGATGGTGCT TAGCAACCAA CTACTTATTT 1800
TCTTTAGTCT TCCTACAGGG TAACCACGAA GTCTTTCTGC AGGCCACTTA GAAAATATCT 1860
GTATGCCTCC TTCCACTCTC ACAAATTCAA ATTTTCCCTG TTGTTATTTT GAACATCTTC 1920
TTCCATGCTG ATGCTTAGAA GTCGTTAAAG CAGCCCCTAA TAGCTATTTT TAAATCTTTA 1980
ACTGTTGATA AGTGAAACTG AGAATTTTTT CTTTCACAAT CCTTTTTTTT TTTGTTTTGT 2040
TTTGAGACAG GGTCTTGCTC TGTTGCCCAG GCTGGAGGGC AGTGATGCAA TCACAGCTCA 2100
CTGCAGTCTC AATCTTCCAG GCTCAGGTGA TCCTCTTGCC TCAGTCTCCT GAGTAGCTGG 2160
GACTACAGGC ACACACCAAC ATGCCAGGTT AATTTTTGTA TTTTTTGTAG AGATGGGGTT 2220
TTGCTACGTT GCCCAGGCTG GTCTTGAACT CCTGGCCTCA AACCATCCTC ACGCCTCAGC 2280
CTCCCAAAGT ACCAGGATTA GAGGCATGAG CCACCGTGCC TGGCCTTTTT CACAATCTTA 2340
AGCATAAGCT TGGTAGACCA TAGACCCCCA GTAAGTGGAA GCTAGTGTAA TAATATTATT 2400
ACACTGTTTT CCTCAAAATG ACCCTGCGAG GTGATTGTTT CACATCAGCT CATGCTCAGG 2460
CCCTGTTATT TCTGCATTTA TGTGGACAGA GAATTCAGGA GGAATAACCA GTGGTAGACA 2520
TATGAACACT CCTCACTTGG AAGGACCATC CTGTCTAGGG TGAAGACCTT TTTTGACTGT 2580
CCATGATTCT GTTTTTTTTT TCTCTTCAAT ACATATGCTG CCAACATTCT TCTAGACTAG 2640
CCAACTAGTT CGCAGGGCTT CTTCCCATCC GTCTTGCCCT GTAATTCGAG AGCTCATCCT 2700
ATGGCCTGAC TTGAGATGTA AGGCTGCCAA GACTCTTCCT TTCTCTTTGG AGTCATGGAG 2760
CACCTATTTC CACTCACCCA CCCATCCATT CATTTGTTCA TTCTTTTAAA GAAAATAAGA 2820
TAGGGTTCCT GGGTTCAAAG AGCTTGCAGT CTAGGGGCAG GTGCGGTGGC TGACACCTGT 2880
AATTCCAGCA CTTTGGGAGG CCGAGGCAGG CGGATCACTT GAGGCCAGGC ATTCAAGACC 2940
AGCCTGGCCA ACATGGCAAA GCCTCCTCTC TACTATTAAC AAAAATACAG ACATTAGCCA 3000
GGCATGGTGG TGCATGCCTG TAATCCCAGC TACTTGGGAG GCTGAGGCAT GAGAATCACT 3060
TGAACCTAGG AAGCAGAGGC TGCAGTGAGC TGAGATCGCA CCATTGCACT CCAGCCTGGG 3120
AGACAGAGCC AGACTCTGTC AAAAAAAAAT TGTGGGTGCA ATAAGATCTG AGCACACATG 3180
ACCCTGACAG AGCAGCATAG CAGAGGCAGC GTGAGGGGAG CCGCTGTCCA AAGGTTTTGG 3240
AGGGAGAAGT CACTGCTGCC GCAAGTGACG AGAAAAGCCT TCTGGAATGT ATGATGGGGA 3300
GGACTCTGAC AGGTGGTGAT GGTGAGGGGA ACATTCCAGA GCATGGAGAA AGGCGCAAAG 3360
ATATGCAGGA AGAAGCTGTG AATGAAGACA GCGAGGAGTC CAGTTCACCT GGAACGCAGT 3420
GTGTGGCAGA AAGAGCACTG CATGTGGGGT GTGGAGACTG GGTTTCCGTT CTGCCACCTT 3480
CCCAGTAAAA AACAAAACAG TGCCAGACTG GCACTGAACA GATGACTTAG CCTTTCTAAG 3540
TCTCAGCTTC CTCGCCTGAA AAGTGAGGTC TTCTACTCAC ACAGCTGTCG TGACAGTTAA 3600
ATGAGACCAA TGAGTGTACT GTGGCTAGAT CATTTTTGAA ATATTAACAG ATGCCCACCT 3660
CCCTTCTCCA TCTGCCCTCC ACAATTTCCA CTTTTCTCTT CCTACTCCTG GCCTGTTCTC 3720
CTGGCCACAG GGCAAGAATG TGGCAGAGCA CAAAGGAGAG AAAAAAGGGA GTCTCTCTCT 3780
CTCTCTCTCT CTCTCTGTTT CAAAACCCCA CAGCCTTAGG GAAATGGCAA GGACTCTGGA 3840
ATTATTTAAA TTGTTGAGAG TTTGATGAAT ATTAGGTTTC TCCAGATTGT CACCTGGATT 3900
GACCCCAGGA AAGATGGGGC AAGGGTGGGG GTATTGAGGC AGTGGTCCTT GACAGCAGGG 3960
CCCGCACAGC CTCCTTGACA GGTGAGCTCT AAAACTCACC TTCTCTAAAG GACATGTGCC 4020
TGGACCCCCA CCCCTGGAGG TCACACAGCT TTAGAAAGGA AATGGCTCTG CAGTGAGCCT 4080
TGGCAAACAA GGCCATAGAG AGCCTCACTG AGAATCCCAC ACTCTACCCT AGCCAGAAAA 4140
CCACAGAATG ATTCCCCTCC TCCAAAGGGT GGCACCGGAA GTGGCCAAGT GAGCTGGAGG 4200
ATCCATGCCT GAGGGCCCAC AGATGACTCG GCAAAGACAG ACGCATGGAG AACCAGGCAC 4260
ATCCCAGACT CCACACCAGC TTGACATTGT TGAATCCTCA AATCTTCCAT TGCAACCCTT 4320
GAGAAAAAGG ATTCAGACTG AACGAATAAT CAAATTTCTG CGGCTTCCAA GAAATAGGAA 4380
CTCTAAGTAG AAATGAAGTT GTTAATAAGA AAAAATACTC AAGGAAACAT CTTTCTTGCA 4440
CGTCAGACTT GTGAACCGAG ATGTATATCC ACTATGGTAC TTTAAAAAGT TAAAACTTAA 4500
CATTTAAAAA CTTAACATTG ACGTGCAATG TGATGAACTA AAATCAAAAC AAAGCTGGAA 4560
AGCTAGGGCA GATGGGGTGT GCACTGCCCT GGAATAGCAA CCTACAAGGG CTCTGAAATG 4620
GAGCCTGGCT CTTAGGATAC TTCAATTCCC TATTATCAGC CTCAGAACAG TAAAACTGCG 4680
GCACAGCTGT TCTGCCTGTA AAGGGCAGCT ATGTAGGGCA GTTTTCCCAG AAGCTTTCTG 4740
TGCTCCCAGA TCAGCTCCAT AAAAAAGTAA GTGTTCTAAA TATCAGGCAC GTCAATACTG 4800
ACAACCACAG CAAATTTAAC GCCAAACGTT TTTATCATTG CAGCAGATGG TAGCCTGTTT 4860
GTGAAATGGC ACTTCACAGA GCAAGGGTGC CCTGCCACAC TTGAAATAGC AGGGACCACT 4920
TATCATCCTG AAAATCAGAG GAAGCATCAA GTTCTCAGAA AACCTTCGGG GCAACTTAAC 4980
TGTTTCTTAG CAGCAGCTGC CTGGGTGAAG ACATCATTCC ATATCTGGTG CTATCCTCCC 5040
TTCCTTAGCT GAGCGTTGTT CGTTGATTCA ATTAATTAAT ATTTATTGAA CACACTCTCT 5100
GGGCTGAACA CCATGATAGG AGCTGGGGAT ACAGCCAGGA ACTTAAATAA TTATTCCAGG 5160
AACTTAAATA ACTATTATAA TATGTTAGTA ACAATAAACC TATAAGGTAA GAAATTATTT 5220
GTCTCCTCAT TTTACAGATA AAGGAATTGA GATTTAATAG AAGGTCAGAC CAGCTCGGAT 5280
GGGCAGACCA GAATTCAGAT TATGCTGGAT CTAAAGTGCA TGCTCCTAAC CACCACATTC 5340
CAAGGTCCAG TGAGGAGGAT GAGCAGGTTG GGGTTCTGAG ACAGAGTGAG GGAAACTATG 5400
ATTAGGTGCC AAGTGAGAAG TTGAGAGGGC CCTTATCTGC CACAGAGGGG CAAGGCAGCT 5460
TCCTAGAGGA AGCCACATTG AACAGAAGGA TCATCAAACT AAGTGTGTGA GTCAGAGGAT 5520
TTGTTCTGGG TCTTGGGTCA TGGAAGTTAG TCTACTCTCT TTATGAAATC TATACTCAGT 5580
GCCTATGTTT TTCTCATATT TTTCTTCTGT GGAGCAAGAA TCGTTGCTTT TTATTGAGGG 5640
TGATTTTTTT TTTAATACCT GTCTTCTTAC CCTGCAAATA TAAAGATAGA ACATTCTTGT 5700
TCACCGACTG TGGATACTGC CTCGGGGTAA GGTGGTGGGT GGGGCCAACA CGGTCAGGGC 5760
CAGCGGTCAT GCAGGCAGCA CTGTGGCCCC TGTCCAGCCC CTAGTTAGTG CTATAACCTC 5820
TGGCCCTAGA ACGAGGCTCT GAGCAGGCAT CTGCAGCCTC TGAAAGTGCC ATGAGATGTG 5880
TCTGTGTGAG GCCACCCTGC CTCACCCATG GCCAGCATGT GACCTCACTA AGAGTCGGTG 5940
GGGACTGGAG CCACAGCGAA GGAGGCAGCG TGCTGGAGAA GACAGTGCGA GGCAGCAAAT 6000
GACCATTATT ACTGATTTGC CTCCGACAAG AAAGAAAAGG ACAGCCTCTG TTTAGAAGTA 6060
AAATTAGACA CGGAGAACCA ACGCACTCTC CTATTCTCAG CTCTTGAAAG TGCCCAGAAG 6120
CTCCTTTCAG CACTACTACT GCTACCTACC GTCTTGTCTT CTGTAATTAA ATCTGGTTTT 6180
CCCACAGGCG TTAGGATTAA AGATAACTAA GAACAGTTAT TTAATTATGC TTTCAACATT 6240
GTTTAGTTAC AATGTCTCAA TATGTTCCAG AAATTACTAT ATGTGTTTAT TTTTAAAGTA 6300
TATTTATAAA GTATAGTTTT AAATATACAG TACCTCTGCT ATTTTGAAGA CAATATATTG 6360
TACAATATCA TTTTCTCTTT TTGATTGCAA ATATGTAGTA TTTCACCTAA CAGGGACTGA 6420
ATGCATTTGG AAAGAAGATA GTTTGGGAAT CTCACCATTT GTAATGTTTC TTCGGAAAGT 6480
ATTAGAGATG AAAGTATTGT ATCTAGTCTT AAATCAAATT TTAGTAACAC ATCAATTAAG 6540
GAGAGAATGG CATGCATGTG TAAAGGCAGT TGTGATTTTC CATCAGTCTG TTTTTTGGGG 6600
TATATTCGAA CTGTAATTCA GTCATATGCA CCAAACTGGT AGATGTTTTC TTCTCTGTAG 6660
CTACTGATGA AAGGAGTCCC TCTTGTACTC TAGAAGCTCA CAGAGTTGTT TAATACTCAG 6720
GGAGAAATGG GGCCACCCTC TGGGCCCTTG CGGCTTGCTT ATGATGTTTT AAAGAGCCCT 6780
GTCTGGAACA AAACAGGCAA CATTTGTGTA ATTGTAAACA GATCCTTAGA TCCTTTATAG 6840
CTGAGATAAT CTGTACAAGG AAAGAGGCTC TCTTTATTCT TTTAATGGAA TCAGGATCTT 6900
GTTCACTTAC TCTCTGTCTG TCGGGGCTGT GGAGTGTGCA TCCGTGTGTC CTGCTGAGCA 6960
AATGCTCATA AAGCAATACC CCACGCATTA GAAAACCTTT GCTACCCAGA GGCAGGGCAC 7020
AGGGAGCGCA GAACTGAAAT CTGTTATTGA TGTCTGTACA GGTGGGTTAG ACAGAGCACC 7080
CTGAGGGATG TCCAGGTGTG GGAGAGAGGA CTTTGAAGTG GGCTTTGGGA AGGCAGGTTC 7140
CTGACCTTCT GCCATTTACA AATTTCATGG GCTTGGTCTA GTCCCATAAC TTTTCAGGAG 7200
CAGGTTTCCT GGTCTATAAA ACACATTGGA GCAGGGTTTT TATACCGAGG TGAGTGTAGT 7260
GTCAAGTTTA GTGACTATGA ACAGAGACCT GGATCCAGCT TGTGTAAGCT CAAGTCTGGC 7320
AGTGTTATTT CACAGCTTTG TGACCTTCAG CAAATCACTT AGCCCAGCAC TGCAGTTTTG 7380
ATTGAATAGA TTTAAAACCT ATCTCATAGA TTGTTGTGAG GACTAAATGA GTTAATATTT 7440
AGAGCCTGAC ATCCAATAAA TGCTACACAA AGAAGCGTTC CTGTTGGTGG GAGTGTGAAT 7500
TAGTTCAACC ACTGTGGAAG ACAATGTGGC AATTCCTCAA AGACCCGGAG GCAGAAATAC 7560
CATTTGACCC AGCAATCCCA TTACTAGGTA TGTGCCCAAA GGAATATAAA TTATTATTTT 7620
ACGAAACTTA TTCATTATGC ATGTGTATGT TCATTGCAGC ATTATTCACA ATAGCAAAGA 7680
CATGGAGTCA ACCTAAATGC CCATCAATGG TAGACTGGAT AAAGAAAATG TGGTACTTAT 7740
ACACTGTGGA ATACCATGCA GGCATAAAAA GGAACGAGAT CATGTCCTTT GCAGGGACAT 7800
GGATGAAGCT AAGGCCACTA TCCTCAGCAA ACTAACGCAG GAATAGAAAA CCAGATGTTG 7860
CATGTTCTCA TTTATAAGTG AAAGCTGAAT GATGAGAACA CATGGACACA TGGTGGGGAA 7920
AACACCCACT GGGGCCTGTC AGAGGGTGGA CTTTGGGGAG GAGGGAGAGC ATCAAAAAGA 7980
ATAGCTAATG GATGCTGGGC TTAATACCTA GGTGATGGGA TGATTTGTGC TGCAAACCAC 8040
CATGGCACAC ATTTAACTAT GTAACAAACT GGCACATCCT CCACATGTAC CTCTGAACTT 8100
AAAATAAAAA ATAATAAAAA AGAGAAGTGT TGGCCAGGCG CGGTGGCTCA CTCCTGTAAT 8160
CCCAGCACTT TGGGAGACCA AGGCGGGCAG ATCACGAGGT CAGGAGATGG AGACCATCCT 8220
GGCTAACACA GTGAAACCCC ATCTCTACTA AAAATACAAA AAATTAGCCA GGCATGGTGG 8280
CACTTGCCTG TAGTCCCAGC TACTCGGGAG GCTGAGGCAG GAGAATGGCC TGAACCCAGG 8340
AGGCGGAGCT TGCAGTGAGC TGAGATCGCG CCACTGCTCT CCAGCCCGGG CGACAGAGCG 8400
AGACTCCGTC TCAAGAAAAA AAAGAGAAGT GTTCCCTATC GTCACTACTT TTGCACTTTC 8460
TGAAACCCAG TTCTGCAAAG ACATAATTGG AATATCATTT TAAAGTGTGT TGATTATTAA 8520
AAATAACAAG CAAAGATATG CTACATGTCA ACATGCAACA CACTGACAAC TTTTCAATTT 8580
GTGCTACCTG TTTAACTTTG CTTTGTATAG ACATGGGACA AAGTTTCTTC TGCCACATTT 8640
TCTTGCAAAT GTATTAATAT TGATTAAGAG TGCTGGTGTT TCTTACAATT CAGGCCTACA 8700
CATGTATCCC CAGTGCAGAA TTGTACAGGA CACTACACTA TTGTAGAACA GATGTGAGAG 8760
CCTTAATTAA ACGGCAAGAA AGCCAGACAG GCTCAGGTGC TTTAATATCT GATGTTGGGA 8820
GAGTTGAGCA ATAAAAAGTG GGCCACTAGC ATGTCACATA CCACATACAC ATATGTATGT 8880
CATATAATAG AGAGTTTTTA TGCCCTTCAT AAATTTTGAT GCTTCTTATA TGACTTTTGC 8940
ATTTGTCATA AAGAATATGT TAGATATGGT TAGTGATTTG ACGTGAAAAC AGCCTGCTTT 9000
TTTTTTTTTT TTTTTTTTTT GAGATGGAGT CTCACTCTGT CACCAGGCTG GAGTGCAGTG 9060
GCATGATCTC GGCTCACTGC AACCTCTGCC TCCCGCTTCA AGCGATTCTC 9110
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