| Tag | Content |
|---|
EnhancerAtlas ID | HS133-02188 |
Organism | Homo sapiens |
Tissue/cell | melanoma |
Coordinate | chr1:144526640-144534670 |
Target genes | |
TF binding sites/motifs | | TF | JASPAR ID | Coordinate | Motif Sequence | Strand | -Log10(p-value) |
| Nkx3-2 | MA0122.3 | chr1:144527210-144527223 | TTTAAGTGGTTAA | - | 7.12 | | Nr2f6(var.2) | MA0728.1 | chr1:144530380-144530395 | GAGGTCAAGAGGTCA | + | 8.55 | | PROP1 | MA0715.1 | chr1:144529741-144529752 | TAATTTGATTA | - | 6.02 | | RARA | MA0729.1 | chr1:144530380-144530398 | GAGGTCAAGAGGTCAAGG | + | 8.44 | | RUNX1 | MA0002.2 | chr1:144529838-144529849 | AAACCACAAAC | - | 6.02 | | STAT3 | MA0144.2 | chr1:144530795-144530806 | CTTCTGGGAAA | + | 6.62 | | mix-a | MA0621.1 | chr1:144529735-144529746 | CCTAATTAATT | - | 6.32 |
|
| | Number of super-enhancer constituents: 18 | ID | Coordinate | Tissue/cell |
| SE_11964 | chr1:144533110-144541143 | CD3 | | SE_14561 | chr1:144532565-144541703 | CD4_Memory_Primary_7pool | | SE_15455 | chr1:144532792-144541924 | CD4_Memory_Primary_8pool | | SE_15882 | chr1:144532843-144542115 | CD4_Naive_Primary_7pool | | SE_16425 | chr1:144532829-144543214 | CD4_Naive_Primary_8pool | | SE_17054 | chr1:144533071-144540733 | CD4p_CD225int_CD127p_Tmem | | SE_17469 | chr1:144532743-144541930 | CD4p_CD25-_CD45RAp_Naive | | SE_17945 | chr1:144532487-144542116 | CD4p_CD25-_CD45ROp_Memory | | SE_18607 | chr1:144532729-144543281 | CD4p_CD25-_Il17-_PMAstim_Th | | SE_20383 | chr1:144533123-144541014 | CD56 | | SE_20952 | chr1:144532595-144542049 | CD8_Memory_7pool | | SE_21567 | chr1:144533141-144541936 | CD8_Naive_7pool | | SE_22023 | chr1:144532818-144542018 | CD8_Naive_8pool | | SE_22494 | chr1:144532830-144542021 | CD8_primiary | | SE_30007 | chr1:144533029-144541934 | Fetal_Muscle | | SE_36968 | chr1:144532904-144548195 | HSMMtube | | SE_51650 | chr1:144532611-144541131 | Skeletal_Muscle | | SE_63499 | chr1:144533390-144534555 | HSMM |
|
| | Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder | | Number of disease enhancers: 4 | Chromosome | Start | End |
| chr1 | 144532600 | 144532972 | | chr1 | 144533627 | 144534178 | | chr1 | 144532044 | 144532420 | | chr1 | 144534589 | 144534653 |
|
Enhancer Sequence | CATAACCCCG TCTCTACTAA AAATACAAAA ATTAGCCGGT CATGGTGGTA CATGACTGCA 60
ATCCCAGCAA CTCGGGAGGC TGATGCAGGA GAATCGCTTT AACTCGGGAA GTGGAGGTTG 120
CAGTGAGCCA AGATTGCACC ATTGCACTCC AGCCTGGGTG ACAGAGCAAG ACTTTGTATC 180
AAAATACATA AATAAATAAA TAAAAAATAA AAAAGACTTC CCTGATCGAA ATTTAAATCA 240
ATTTCCCCTT CTAATTCTAA AGCAGCCTCC AAGATCCTAT AGGGTTTGGG AGAAAATTTG 300
ACTTAATTGT CCAAACTTTT AGCCCGAATA TTATGATTTT TATCAATTAA TTCACATGTG 360
GTGTAAGAAG GCAGGGCCAC TAAATGGTTG AAAAGGGCGA ATTGGAATAA TTCTTTAGAG 420
GATTTTTAAA AACAGAGTAA AGCAGACAAT GAAAGGGTCT GCATTTTGGC CAAATACCTC 480
CATGTTGCCA TTCCCCAGGT TGTTCCCAAA AATGTAGATT GGAGAATTCA GCAATGCACT 540
TAAAAGGCCA AGCAAATCTG TCTTTGGTAT TTTAAGTGGT TAAGATTTAT TGATTGATTG 600
ATTGAGACAG GGCCTCACTC TGTCACCCAG GCTGGAGTGC AGTGGCTCCA TCATGGCCCA 660
CCACATCCTC AACCTCTCAG CTCTAGCAAT CCTCCCACCT CAGCCTCCCG AGTAGCTGGG 720
ACCACAGGTG CATGCCACAA TGCCCAGCTA ATTCTTTGAT TTTTTGTTTT GTAGAGAGGA 780
CATCTTGCTG TGTTTTCCAG GCTGGACCTG AATGAACTTC TGGGCTCAAT CAATCCTTCC 840
ACCTCAGCCT AACATTTACA CTGGGAGCAG AGATGCATTT GGAGTAGGTG ATGATTTTGG 900
AATGCTTTAG AAGCAACATA GGTATCTGAT TTCATCAGGT CAAGCCATCA AAAATGACCA 960
ATAAATCTCT GACCTCTTAG AAGCAATTTG AAGACCCAAA TTTTGGCCAT CATCAAAATT 1020
CGTGTTCATT CAAAATTAGA CATTCTGGAG AGCAAGGACA ATCATTTTGC TGATGCTGCA 1080
GCTAAGAATG CAGCTCTGAA GTTGACATCA GACACAGAAC TCCTCGAAAT GACCTTGCTG 1140
ACTTATGACC CATTGAAGAC TTCATTAGAA GTACAAGTGG GCTGGGCATG GTGGCTCATG 1200
CCTGTAATCC CAGCACTTTG GGAGGCCAAG GCTGGCAGAT CACCTGAGGT CAGGAGTTTG 1260
AGACCAGCCT GGCCAACATG GTGAAATCCT GTCTCTACTA AAAATACAAA AATTAGCTGG 1320
TGTGGTGACA CATGTCTATA ATCCCTGCTA CTTGGGAGGC AGAGGCATGA GAATTGCTTG 1380
AACCTGGGAG GCGGAGGTTG CAGTGAGGTG AGATTGCACC ACTGCACTCC AGCCTGGGTG 1440
ACAGAGCAAG ACTCTGGCAA AAAAAAAAAA AAAGAAGCAT AAGTGGGAGC TCCCAAGCAG 1500
GAGAGGGATC TCTGGAAGGA TAAAGGGAAC AAATTTCTTC CAGAAACAGT CATATGGTAT 1560
GGGCCCAATG ATACACTGAT CTATCCCTTA GGCTTCAATT ACCCTTTTAC AGTACTTCAT 1620
AAGCTGACTC ATTGGAATTC AGACAAAATG TTGGCATGGG GAAAGCAATG GTATTGAAAA 1680
TCATTGCCTA TGATTGCAGA AAATGTTTAG TCTTGCCATA CTGTCTGTCC CAAACATAAT 1740
CCTGGAAAAC CCCTTCATGG GTCACAGGGA CATTTTGCCT TTGGGACCCT TCGAGACATG 1800
GCAGTTAGAC TTTATCCAGC TGTCTCCATC TCAGGGTCAC AGATACTTTC TGGTGCTAAT 1860
TTGTATATGC TCACTGGGGT GAGCATTTCC ATGCTGATGA GCCACAGCCC AAGTAGTAGG 1920
TAGATTGTGA TTAGAAAAGG TAATTCCTCA TGGGGGGTGC CATCTGAACT CCATAGAAAC 1980
TGAGGAACAC ACTTCGTTGG TCAGGTAATT TGATCCATTT GTAACATTTT TGCCTAAGTC 2040
CCAACATTTC CATTGTGCCT GTCACCCCTA ATCCTCTGGG CCGATGGAAT GCACTAATGA 2100
TACAATAAAA ACTCAATTGG CAAAGCTAAC AGAAGTTTTT AACCTTTCTT GGACAAGGAT 2160
CTCCCACTGG TTGTGGAAAA TGTCCACACT CTCCCTCTTT GAAATAATAA CAGGAAGACC 2220
CTTGCAGTGG TTAGATGAAG GCGCTTATGA ATCTGCACTT CTTAAAGGTG ACATTCTCCA 2280
TTACTGCTAA GATCTCACAG AACTTACTAA GAACTCTACA TTAACAAAGA ATTCCATTCA 2340
TAATGAACTC CTGGGAGATG AAAATATCAA AAATCTTGGC CTATAACCTG GAGATGTTGT 2400
TGTTTACTGG AAACAACATC AAATAAAATA TTCTTCCCAA GACTGTTGGA AGGGACCACA 2460
TCAGCTATTA TTATTACTTT ATATATTTTT TTGAGATGGG ATCTCATTCT ATTCCCCAAG 2520
CCAGAATGCA GTGGCACAAT CATGACTCAC TGTAGCCTTG AACTCCTGGG CTCAAGCCAC 2580
CCTTCTGCCT CAACCTTCCA AATATTTGGG ACCACAGGCA TAGGCCACTG CACCTAACTG 2640
ACGACAGGTA TTACTGACCA ATCTGTGCCA GTAAACTTAA GGGCGTTGAC ACATGGATTC 2700
ATGTTTCTCT TGTAAAAGGC AACCCTACCA GAGTGGACAT CTGTCAGTGG AGATTTTCAC 2760
TTAAAGGTAA CTCACAATCT TCCTGACAGA GATGGCAAGT AGCTGACATC TGGTGTAGTC 2820
CACTTTCACC CAAGATACTG GCCTGTATAA TCAGTTACAA TTCCAGTGCT GACCGTGCCT 2880
GAGAGAGTTA GTCTCTTTTT TGCTGACTGG AATACATACA CCATTAGGGC TCCTTTAAGT 2940
TGTAGGGGTT GTCTCTTGGT GGTTTTGGTA AAATCACCCT ATATGCATAT TCTCTTAAGA 3000
TATGACACAC TACTCCTGTT GCGTGTATGT GTATATACAT ATACATACAT ACATACATAG 3060
CAGAATACCT GTGATCAGAT TTCTGTTTTA CTGTCCCTAA TTAATTTGAT TACAGCAGGG 3120
AGGGATAATT CTCTGATTAG AATCTCACAA ACCATTACCT CTGTGGGAAA TTTGACAAGG 3180
TTCCAGGTTT GCCACTCAAA ACCACAAACC ACTTTTGACC ATAATGACCC ATTGGTACAT 3240
CCTGTGCTAA ATTTCACCTG TATTCCTCCT GATTGCACTC ACGATGCAAC TCAGGGTCAT 3300
ATCAAGCAAA ACCTGTTTAT CTAATCTGTC TGACTCACCC TAACTTTCCT GCCGCACGTC 3360
TCAGTTTAAC CCATCGTAAT CGTATTGTCA AAATAACTGC CTGTAATCCC AGCACTTTGG 3420
GAGGCCAAGG CAGAAGGATC ACTTGAGCAC AGGGGTTTGA GACTAGCCTG GGCAAAATGG 3480
TGAAACACTG ACTCTATAAA ATATATACAA ATTAGCTGGG TGTGGTGGTG CCCACCTGTA 3540
GTCCCAGCTA CTCAGGAGCA TGAGGTGAGA GGATGACTTG AGCTAAGGAG TTCAAGCCTG 3600
CAGCGAACCC TGATGACGCC ACTGCACTCC AGCCTGGGCA ACAGAGTGAG ACCCTGTCTC 3660
AAAAAATAAA TAAATAAGCT GCGTGTGGTG GTGTGTGCCT GTAGTCCCAG CTGCTTGGGA 3720
GGATGAGCCA TTGAGCCTTG GAGGTCAAGA GGTCAAGGCT GTACTGAGCT GTGATCTTGT 3780
CACTGAATTC CAGCCTGGGA GACAGAGTCC TTGTCTTAAA AAGTAATTAT AATAAAAATA 3840
AAAAGTACAA AACCAACCAA ACAAAAAATT GTTTCTTCAC TCTGAAATAA CAGTGGTTAA 3900
CACCATGATG CCACTGGAAA GTTAAAAGAA AAACACTCCC TCCTGCTATC AGGATCCAAC 3960
CTGCCCTCTT GCTCTAAATT TCTGACCCAT GGTTTAAATG CCCAAAAGCT GATGTACTCA 4020
AATTATAGCG CACTTACTTG TTCGGCGTTT ATTTTTGTCT CTTGAAAAGA TCACCATCCA 4080
TGGCCCTATA AATGTCGAAG GGCATGGAAT GATGAAGTGC AATGTCATTA TTGTTATGTA 4140
TCTCTCATCG TTTTACTTCT GGGAAAACTA ATTTCATGGT ATTCTGAAGA GTAGAGATGA 4200
TTCAATAAGT GACAGCAGCT GTAGACTTAA CTGAGGCCTC TCTCTCTCTC TCTCTTTTTT 4260
TTTTTTGCCA CTCTATGATG CCCTTTTTTT TTTTAAGACC GAGTCTCACT CTGTCACCCA 4320
GGCTGGAGTG CAGTGGTGTG ATATTAGCTC AGTGCAGCCT CAAACTCCCA GGCTCAAGCA 4380
GTCCTCCTAC CTCAGCCTCC TGAATAGCTG GGACTAAGGT GTGTGCCACT ACACCTGGCT 4440
AACTTTGTAT TTTTTGTAGA GATGGGGTTT CACCATGTTG CCCAGGCTGG TTTTGAACTC 4500
CTGGACTCAG GCAATCCACG TATCTTGGCC TCCTGAAGTG CTGGGACTAC AGGTGTGAGC 4560
CACCATGCCT GGCTGTAATG CCCTTTCAAT TGGACTTTTG GGCATTCTTA AAAATTCCTC 4620
AGTGAGGTGG CTTCTTTCCT CCCCTGTCCC CTGCTTGGGA CAGGACTATC CGGGAATGAG 4680
CCTTTCTGGC AAAGAGGGAC AACCTTGACT TAGCTTTTGA TCATCGATGC TTTCAAGAAG 4740
AAAGATTAAA AAAACTTTTT ATCTGAGGAA TGTGAGCCCT TTCAAATGAT CAGGCCCAGA 4800
GAGACGTTAA ATCGAGACAG CAACCACTTT CCGCTCCTTC CTTTTGAGCT GCGCTGAGCT 4860
ATGTATTCAT CCGTTGAAAC TGCTTGCTAT TGCCTCAAGT AGCTGTAAAT TAACCTAATA 4920
ATGCCACACC AATCCCTATA CCCCCATACC CTATAACTTA ACAACATATA GCCAATCACC 4980
AAGCAATGTT ATTTCTGTAA ACCAATGAGA ATTCCTGATA GGCACCTATC AGCCCACTGT 5040
CTGTCCCTGC TTTTGAACTT TAAAAACCTG CTTGTGGGCA GGGTGCGGTG GCTCACGCCT 5100
GTAATCCCAG CACTTTGGGA GGCCGAGGCA GGCGGATCAT GAGGTCAGGA GATCGAGACC 5160
ATCCTGGCTA ACACGGTGAA ACCCCGTCTC TATTAAAAAA ATACAAAAAA AATTAGCTGG 5220
GCGTGGTGGC GGGTGCCTGT AATCCCAGCT ACTAGGGAGG CTGAGGCAGG AGAATGGCGA 5280
GAACCCGGGA GGCGGAGCAG AGTTCGCGCC ACTGCACTCC AGCCTGGGCG ACAGAGTGAG 5340
ACTCCGTCTC AAAATAAATA AATAAATAAA AAATAAAAAA TAAAAACCTG CTTGTGACAA 5400
AGGCAAAAGG GAGCTCAGAT CCAAGCTTCC TTGGTGTGAG TCTTCCAGGC AGTTGTCTTC 5460
ATGTTGACTC AAGTAAACTC TAAATTATAT TTTGTGCTTC AGCCTCCTTC TTTTAGGTCA 5520
ACATGTTCAA CAACAGTAGA ATAAATACAT AAGTTAATGT ATATTCCTAC AAAGGAATAC 5580
ACGTAGAACC AAATAACCAT ATGAATAACA TGAAAAATTC ATAGACATAG GACTGAGTGA 5640
AAGAAGTCAG ACCTATGCCT CTGCTTCTGC AACCGCCTTT GCAAAAATTA CAACTGGGAC 5700
AATTACCACA GTGAAAGAGA TCTGATCTAA CTGATTCCAT CTTGCTTCTA ACGTACAAGC 5760
TGTCCTTGTT GATTGCTGGG CACAGGCCGA AATAACTTTG GGAGGAAATT AGTTTATGGT 5820
TTAGCTGTGA AACAAAGATG ATAATATCCC TGTCCCGAAG CAAACCCCCT TCCTGCCTGG 5880
GGACTAGACT GCCTTTGCCG GACTAACAAA TTAGCCACGA GATTAGAAAT TATGGTTTAG 5940
GAGTCATGTA GCCTCTGGCT GCAAGATTCT AAACCTCCCC AAATTGTTCC TGGAGATCAC 6000
ATCGTTATTG GAAAACCTAA GATCAGTGCT TGAGATATTT TGCCGACCCT GCACTCAGTG 6060
GATCAGCTGG CACCAGCTAG ACTGATAACC TGGCTCAGCT GGTCTTGTGG CCCCCAAGCA 6120
GGAACTGACC CAGCACAAGA CCACAGCTTC AGCTCCCTGT GATTTCATCT CCGACCTGGC 6180
CAAGCAGAAC TCTCAATTCA CCGGCCCCCA ATCACCAAAT AAAGAGTGCA GCTCTTTATT 6240
GCAATTCCCC TGTGTCGAAA AATTGGCTCT GTCTAGGCAG CAGGCAGGGT GTACCTGTTG 6300
GGCAGTAACA CTCCCCCCAA AACCCACTAC AGACTGTGAC TCAGCTTATA TGAAAGTAAA 6360
GGGCAGGAAA AACTTGCCTG GTAGATTTGC AGAGACGGGG GTGGAAACCA TTAATAAGTC 6420
TGTGGAGTAT TCTCAGAGTT TGGTGTTGTA GTCTACATAT TAAAAGTAAT CAGTTAAACA 6480
CCTGAAATAA AACTTCTCCC AAATATTTTT GCCAAATTTG GATGACTGTG TTTCTGTCTT 6540
CGCAGCATAT AAAGTGTTAA CATGAGGTAA GCGCTAAGGT CTAGAGAAGG CAGTGAAGAG 6600
ATGACAAACT CCAGCACCAT GCCTGAATGT CCAGTGTGCT CTGCTGGGGC AGCACATTTT 6660
TGTACATTGC TGTATCTGAA AAAAACCCTA CAAGATTCAT GAAACTGGAC GACCGTCTTT 6720
ATAATACTCC TAGTGATAAA ACAAGTAAGG ATGGCTGGTT TGCAGTCATC TGAGCAGCCT 6780
CTCTAGTTTC ATAGATACGG TTTCTCTCTG ATATTGAACG ACTTCCAAAT GTCAAGCGAA 6840
ATGCTACATC ACAAGGATAA CCGTATGTGA AAAGAACCGT TTTTCTTTGT AATCCTAAAC 6900
TTTCTAGTCT GAGCTTTAAA AGCCATTATT TGAAGAAAAG CGCACAGGCT CCAGCTGGCC 6960
GCCAAAGGGG TCCTTTGCAT CACAGGCTAA GGACCTACTT CTTTGGCAGA GACCAGGGAC 7020
GGGGATGGGA GGGAAAGGAG GTAGAGTCAG GTGTCACTTC CTCCGCCCGC TCCCGCAGCT 7080
GGTTGGTCGG CCGAGTGGCA GAGGGTGGGG CGGAAGAGCA GATGGGGACG GGAAAGGCGC 7140
TGTCGGTGAC ATCACAGATA GGGCGATTCC TATGCAGAGG AGGCAGCTCA GGGGCTGCTG 7200
CTTCGCCAGG AAAGATTTCT CGTGCTGTGG GAGCTAGTCC AGGACTTCCG GTTGGACGTG 7260
ATAGTCCCAG CTGTGTGTCA GGGCTAGGAG GACTTGAGGC GGCATGGGGG CGGGGTGGGG 7320
GAATGCGCGG GGCAAGTGAC CGTGCGTGTA AGGGGTGAGG CGTATGGAGC TGTGGCAGGG 7380
CGGAGGTGCG TTCATTCATA CTTATGTAAC AGGAGAAAAT ACGGCCATGA AGTTGGTGTT 7440
TTCCGGGGGC GGTTTTTCCA TTGTACTCAG TATGTGCTGA CTGACTCCTG TTACTTCCAC 7500
ATGTGGGGAA ACTGGACTGT AATTTGTGGT GGTGGGGAAT TGCGTTCGCG CTTTCTTCTG 7560
GAGGTTGTAG TGTAAAAAGC AGTTTGTCTA CCAAGTGATA CTTTCAGCTT TTACAAATGC 7620
TGAACAATAT CCGTGGTGTG TTTTCATGTC ACCTCCTCTC CCTTCTTTGT TAGAAAAAAA 7680
TGGAAGAGCA CGTGGATGTT TTGAGATGAG AAGAGGTGCG TTCACCACCT TCACCTCCGT 7740
GTAGGCTTGT TATTAAGGGA AAGGGAACAA AGGAGTCTCA CTTATGTAAG ATGACCTTAC 7800
ATGAGAAGAA GAAATTCGAG TTGGTGAAAA GAAAGAAATT CAATTTCAGC CGGGCGCGGT 7860
GGTTGACACC TGTAATTCCA GCACTTTGGG AGGCCGAGGC AGGCGGATCA CGAGGTCAGG 7920
AGATCAAGAC CATCGTGGCT AACACGGTGA AACCCCGTCT CTACTAAAAA ATACAAAAAA 7980
ATTAGTTAGG TGTCATGGCG GGTGCCTGTA GTCCCAGTTA CTCGGGAAGC 8030
|
