EnhancerAtlas 2.0: an updated resource with typical enhancer annotation in 600 tissue/cell types across nine species

EnhancerAtlas 2.0

Tag

Content

EnhancerAtlas ID

HS133-00741

Organism

Homo sapiens

Tissue/cell

melanoma

Coordinate

chr1:25842660-25844850

Target genes

Number: 25
Name	Ensembl ID

RUNX3	ENSG00000020633
SYF2	ENSG00000117614
RP3	ENSG00000261349
SDHDP6	ENSG00000224183
RP11	ENSG00000259984
TMEM50A	ENSG00000183726
C1orf63	ENSG00000117616
SDHDP1	ENSG00000238084
RHCE	ENSG00000188672
TMEM57	ENSG00000204178
LDLRAP1	ENSG00000157978
MAN1C1	ENSG00000117643
SEPN1	ENSG00000162430
RP1	ENSG00000255054
FAM54B	ENSG00000117640
AL020996.1	ENSG00000223474
C1orf135	ENSG00000127423
PAQR7	ENSG00000182749
STMN1	ENSG00000117632
PAFAH2	ENSG00000158006
EXTL1	ENSG00000158008
TRIM63	ENSG00000158022
PDIK1L	ENSG00000175087
ZNF593	ENSG00000142684
CEP85	ENSG00000130695

TF binding sites/motifs

Number: 13

JASPAR ID

Coordinate

Motif Sequence

Strand

-Log10(p-value)

FOXF2	MA0030.1	chr1:25843874-25843888	CAATGGTAAACAAG	+	6.12
Foxd3	MA0041.1	chr1:25844756-25844768	AAACAAACATAC	-	6.37
INSM1	MA0155.1	chr1:25844113-25844125	CGCCCCCTGCCA	-	6.07
KLF16	MA0741.1	chr1:25844109-25844120	GACACGCCCCC	+	6.32
MYC	MA0147.3	chr1:25842842-25842854	CCCCACGTGCCC	+	6.07
MYCN	MA0104.4	chr1:25844771-25844783	GACCACGTGGCG	+	6.07
MYCN	MA0104.4	chr1:25844771-25844783	GACCACGTGGCG	-	6.07
NFYA	MA0060.3	chr1:25844276-25844287	GGCCAATCAGA	+	6.02
RAX	MA0718.1	chr1:25843668-25843678	GTTAATTGGC	-	6.02
RREB1	MA0073.1	chr1:25843377-25843397	ACACCCAACACCCAACACCC	+	6.2
SP8	MA0747.1	chr1:25844109-25844121	GACACGCCCCCT	+	6.27
TFAP2A	MA0003.3	chr1:25844581-25844592	TGCCTGAGGCT	-	6.32
ZNF263	MA0528.1	chr1:25842753-25842774	CACTCCTGCCTCTCTTCCTCC	-	6.21

HEDD

Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder
Number of disease enhancers: 2
Chromosome	Start	End

chr1	25844225	25844803
chr1	25844544	25844811

GeneHancer

Number: 1
ID	Chromosome	Start	End

GH01I025518

chr1

25844581

25844710

Enhancer Sequence

CATAGTAGGT GCTCAATAAA TGTTTGCTGA ATGAGGGAAA GAGCACTAGA ATCTGACTGG 60
CAGCCTCCGG ATCCTCTTTC CATCCGTAGT CTGCACTCCT GCCTCTCTTC CTCCTCAGAG 120
CCTGCCCAGT CCTGAAGACA CCAATAAGAG AAAAGCTTTC AAAGCTCCTC CCTCATGCCA 180
GACCCCACGT GCCCTTCTCA TTACTCTTAC AGCAATCCTG GGGGGTTGGG AGAGTTACCT 240
TGACCTCACA GATGAGGAAA CTGAGGCTCA GAGAGGCAGG GAACATTTCC CAGGGTCACA 300
TAGGCAGGAA GTGGAGAAGC TGGGATTTAA ACTCAGGCTG GTGTGCTCCA GGGCCTGGGT 360
GCTTCAATCA CAAGATTGTC CTACAAGTCC CCAAGACTGG GTGAGGGTGT CTAGGAAGTC 420
AGGACCCCCT GGATGTCACC CCCTCCCAAT GTGCTGTATT ATCTTGTGGG CAGGAAACAC 480
TGAGGCTCTG AGGTAGGGGC TGAAGGAGCT ATGACAAAGA GGTCACTCTG GGGAGTCCCT 540
AATGCTACCC TTGAATAGCC TCTTCCCCCC ACTGCACCCC AGTTTTTGCT CCTGATGTTG 600
GCCACGCAGC TGCCCCATTC CGTTAGAGTG CTGTCTCCAC AGCTGCTGAC ACCTGTCTTC 660
CCCAGCTGTC CAGGAAGGCA TCTGAACCTG AGTGACCACT TGCAGCTGCC ATGACCAACA 720
CCCAACACCC AACACCCACT CTGGGAGGCC TCACCCTCCA AGGCTTGTAC CAGGGCCTTA 780
TGTGGCTGAC ACTCAGCCTG GCTGTAAGGA AGGGGTCTCT GTCCAGCTCT GTCCCCGTGG 840
CCTGGAAGCT CTCTGGAGGA GACCCTGAAT CCCAATCTTT CCCTGCCACC TCCACCTTCT 900
CTTCTGTACC CCAAGCTGAG ATGGTATCAC CAAGGGTTAG GGTTAGGGTT AGGATCTTTT 960
GGTTGCAAGC AACAGAAAAC CAAATCAAAT GGGATTTAAG CAAAGGAAGT TAATTGGCTC 1020
ATATCACTGA AAACTCCAGA GGGTACAGCT GGCTTCAGGA AGGGTGGACA AAGGGGCTCA 1080
GGTGTCACCA TCAGACCTGT TTTCTCCCCG GTCTTGCCTC AGCTATGTCT CCTTTGAGTG 1140
TTGGCTTCAT TGTCACTCTC TACCTGGTGG CAAGAAGGTA CTGGCAGCCT CTAGTTCTAC 1200
AGCCAGGTTC CCTCCAATGG TAAACAAGCA AAAGTCCTAA GAGCCACTCA GACTGACTCT 1260
GCCTGGCTCT GGCCACCCCT GAACCAGTCA CTGTGGAACA TGACACAGAC TATGGCTGGG 1320
ACTGGACTTG GGCACCCTAT ACCCAAGAAA AAACTGGGAC ACTCTTACCG CAATGGTAAG 1380
CAGGTGCTGG ACACGAAAAA CAGGAGATGC TGCTGACACC TGGGGGAGGC CTGTCCCCAC 1440
CCACTCAGAG ACACGCCCCC TGCCACCGAT CCAGGGAAGT GCGCAGCAGG TCAGCCTTTG 1500
GCTGCCGTCA GTCGGCCAGT CTCCCACATC TCTGGGACTC CTCTTGCCAC GTCGCAGCTG 1560
GGAGAGGCCT AGGGAGAGGG GCTGTGTGCA CGGATTGGCA GTGGGAGAGA GATGTAGGCC 1620
AATCAGAATA TCACGCGGGT TGGAAAGGGG GCTACTGTGC GCGAGGTGCC TTCTCGTGCC 1680
CTGCCTCAGT GGGACCCTCA CCTTAGCTCC GTGCAGGTGA GGAGGCTGGG CCTGGGCCAA 1740
GCTCTCACAG CTACAGGGTG CTGGGTGGAA GGGGGCCTCC TGCACTCGGA GCTCTTGGCT 1800
TGTCTCCACC CAGCAGCTCC CTTGAGGAAG GTGGGGAAGG TCGCAGCTTT GTGCAAAGGG 1860
AGCGAGTACA CAATGTGGCC GCCTCCTCTT TTCCATCCCA TCACCTCTCA TTTCACCAAC 1920
CTGCCTGAGG CTGCAATCAA CACTCCCCGC GTGTGGGGGC GGAGCCAACC CACGAGGCCA 1980
TGCTTCAGGC CCCTGATTGG TTCAGGAGTA GCGCTTGACC TAATGAGGCG CTACCAATGG 2040
GATGCAAAGA GACGTTCCCT GGCCTTCTGC CAGAGCGGTT TCCCTGTTCT CCCAACAAAC 2100
AAACATACCT GGACCACGTG GCGCGAGGAT ATTAAGTTTA AGATGGTGGC AGCAGTTTTT 2160
GAGACCTTGC AGAGAGAGCT GCTGAAAGCT 2190