EnhancerAtlas 2.0: an updated resource with typical enhancer annotation in 600 tissue/cell types across nine species

EnhancerAtlas 2.0

Tag

Content

EnhancerAtlas ID

HS129-01084

Organism

Homo sapiens

Tissue/cell

MCF10A

Coordinate

chr1:46671140-46672050

Target genes

Number: 16
Name	Ensembl ID

IPP	ENSG00000197429
RP11	ENSG00000236111
TMA16P2	ENSG00000232467
RP4	ENSG00000226957
TSPAN1	ENSG00000117472
PIK3R3	ENSG00000117461
LURAP1	ENSG00000171357
POMGNT1	ENSG00000085998
RAD54L	ENSG00000085999
LRRC41	ENSG00000132128
UQCRH	ENSG00000173660
RP5	ENSG00000232022
LINC00505	ENSG00000225667
MKNK1	ENSG00000079277
MOB3C	ENSG00000142961
ATPAF1	ENSG00000123472

TF binding sites/motifs

Number: 8

JASPAR ID

Coordinate

Motif Sequence

Strand

-Log10(p-value)

Nr5a2	MA0505.1	chr1:46671635-46671650	GAGGCCAAGGTCAGT	+	6.15
RFX1	MA0509.2	chr1:46671783-46671799	TGTTGCTATGACAACC	+	6.71
RFX1	MA0509.2	chr1:46671783-46671799	TGTTGCTATGACAACC	-	6.73
RFX2	MA0600.2	chr1:46671783-46671799	TGTTGCTATGACAACC	-	6.65
RFX2	MA0600.2	chr1:46671783-46671799	TGTTGCTATGACAACC	+	6.75
RFX5	MA0510.2	chr1:46671783-46671799	TGTTGCTATGACAACC	-	6.36
RFX5	MA0510.2	chr1:46671783-46671799	TGTTGCTATGACAACC	+	6.67
ZNF263	MA0528.1	chr1:46671938-46671959	GGTGGAGGGGGTAGAGGGAGA	+	7.14

HEDD

Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder
Number of disease enhancers: 1
Chromosome	Start	End

chr1

46671298

46671922

Enhancer Sequence

ATTGAAATGA GAAAACTGGT CATCATTTCT CCCATCTTAC AGATAAAACG TGCTTGCAGA 60
TTCTGAACTC ACATAGGGAG TCAGTGGAAG AGCCACGCCC AGTCTCTGGC TCTCTTCTCT 120
GCCTTGGTGG AAACTATCTG TAAACTTTAA GGGGCTGCAT TTAACTTTTG ATTTTGTCTC 180
TCTGTATTCT TGACCCAGCT TGCCTGGGGC CTGAGGCTGC CCGAGAAAGG GCACAAGGGA 240
GGGAGCCTTC TGGGGCCAGA ATGAGGAGAG ATCCCCATCC TATTTTTTCT CCTTCCTCAG 300
GCCAGGATGT TATTAATATT AATCTCTTCT TGTGCTCTGC CCTGCCTACT GGGTTGCACC 360
CAGGAAGGAC AAGGGGTGGG GCAAGGGATT TGCCTTCGGG CTACTGAAGG CAGGACTGGT 420
TCAAGCCCTC TAAGGACTGT CCTTCAATTG TTCCTCTCCC AGCTCTCCTT GCACAAAGGG 480
GGAAGGCCTA CCCTTGAGGC CAAGGTCAGT CCTGCCTCTA GGCCTCGTCC CTCCTGCTTT 540
CTTCCTCTAC CCTCCATTCA AAGGTTGAGT GAACAAGCCA GACTGGGATA TGTGGGAATG 600
GGAAACAGTG GCAACTTCTT CTTAGTTCTC CCACCCAAAG AACTGTTGCT ATGACAACCC 660
ACCTCCACAG AGGCAGTTTG AGAAAAAGCT TTAGGCAAGG AAGAATGCAC GGGTTCAAGT 720
CTTGGCTCTG CTTCTGAAAC GTTTTGTGGT CTTGAGCAGC ACTCTGTCTC TCTCCTGGCC 780
TCAGTTTTTC CTCCTTTTGG TGGAGGGGGT AGAGGGAGAT GGGGACTGTG AAACCAGATG 840
ATTGTTAAGA ACCTTTATAG TAACAATATT CTGATAGTCC CCGCTCTGGG AGCTCGGACT 900
GGGATTTCCA 910