| Tag | Content |
|---|
EnhancerAtlas ID | HS127-20052 |
Organism | Homo sapiens |
Tissue/cell | Macrophage |
Coordinate | chr21:44929770-44932270 |
TF binding sites/motifs | | TF | JASPAR ID | Coordinate | Motif Sequence | Strand | -Log10(p-value) |
| IRF1 | MA0050.2 | chr21:44930090-44930111 | ATCTGCTTTCTCTTTTTGCTT | + | 6.18 | | MAFF | MA0495.3 | chr21:44930800-44930815 | TAGCTGAGTCAGCAG | - | 6.43 | | MAFF | MA0495.3 | chr21:44930800-44930815 | TAGCTGAGTCAGCAG | + | 6.55 | | MAFK | MA0496.2 | chr21:44930798-44930817 | GCTAGCTGAGTCAGCAGGT | + | 6.01 | | Myod1 | MA0499.1 | chr21:44931709-44931722 | AGCAGCTGTTCCC | + | 6.92 | | Nkx2-5(var.2) | MA0503.1 | chr21:44930589-44930600 | CTTGAGTGCTT | - | 6.02 |
|
| | Number of super-enhancer constituents: 9 | ID | Coordinate | Tissue/cell |
| SE_27259 | chr21:44929167-44938707 | Esophagus | | SE_33898 | chr21:44929876-44931559 | HCC1954 | | SE_35943 | chr21:44929783-44932114 | HMEC | | SE_36970 | chr21:44928858-44934189 | HSMMtube | | SE_51730 | chr21:44929237-44932593 | Skeletal_Muscle_Myoblast | | SE_56062 | chr21:44929376-44934361 | u87 | | SE_63514 | chr21:44929444-44933638 | HSMM | | SE_64394 | chr21:44929820-44932123 | NHEK | | SE_67768 | chr21:44929376-44934361 | u87 |
|
| | Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder | | Number of disease enhancers: 6 | Chromosome | Start | End |
| chr21 | 44929945 | 44930000 | | chr21 | 44930000 | 44931194 | | chr21 | 44929886 | 44931890 | | chr21 | 44931921 | 44932027 | | chr21 | 44930607 | 44930875 | | chr21 | 44932109 | 44932168 |
|
| | Number: 2 | ID | Chromosome | Start | End |
| GH21I006026 | chr21 | 44930246 | 44931646 | | GH21I043509 | chr21 | 44929453 | 44943529 |
|
Enhancer Sequence | GTACTGGGGT AAAAGAATTT ACCAAGACAG TTGTAGGCAA AGAAAGGCAG ATTTATGAGA 60
GAAAGTATGA AAACGCATTC CAAGGTTGCA ATGGGCAGAA TCAGCAGAAG AGGAGCCAAC 120
TGCAAAGAAA CAAAGGCTTG CTGGGGATTT TATAGGGTGG TTCTTAGGCT GCAGAGGGCG 180
ACGTGCAGAA CTAATAACGC CAAGGCAGCC AGGAGCTAAC TTGGAGGTGT CTGGCCATAG 240
CTCGGCCCAG GAAGATCATG AGTTACCTGA GCAGGAGGCC TGCGTGTCCT GGACCATGAA 300
GAAAGTCAAC TCTATAGCTT ATCTGCTTTC TCTTTTTGCT TGCCCTTGGT CCTGCCAGCC 360
TGACTCCTTT TCCCTAATTA GGACTCCACA ATCCCAAGAA GCTAACATTC ACAGACACAG 420
GCTGGGAGAC ATCGGCTGAC GCAGTTGATG AGGGTCCCTT ACGGCACCAA CACCGCTTGC 480
TGAGGCTCTG CTGAGACTCA GAAGGTGCCC TTACATGGAG CCAGAGAACA AATCGAGGCC 540
ACAGGGGGAA GGCAGGAAGA GCTGCTTCAA AAGAGAAACT TCAGGCTCCC ATGAGCCTTT 600
TAACAGCCTC CCTGCAAGGC AGCCACTGAC TGATACCAGC CAGGTGATCA GTACAGGAGA 660
GGACGGGGCC CAGGATGGGG CTATCCATCC GGGAGAGGGG GGTGCTTTAC AGACTTTTCC 720
AGAAGGTCCC CAGGGGAACC TTCACAATTC AAGGGCAGAA AGGATGTGAG GTCTGGTGAG 780
GTTCCAACAG CCAGAGAGGA GCCAGGCAGG TCTGTTCAGC TTGAGTGCTT GGCCCATCAG 840
CAGCTTGCGT TGGGTCAGAG CCTTCCTCCC TCAGCCCCAA CCCCCTCCCT GCTACAGCCC 900
CAAAACAGAC AAGTCTGAAC AGGTGTGACT AGAGGGAGCC AACAGGCAGG GTCCTTGGTG 960
GGTGACACAT GCTCACTCCC GACACTGACT CAGACAGCAG CAGGGAAGGG AAACCCCAAA 1020
CCATTCAGGC TAGCTGAGTC AGCAGGTACA GTGTGGCCCA GAGCACGGGC TCAGCCCAGC 1080
TGACTCCTGG TACCTTGGGG AGGCACTGGG AAGTTTCAGC CAGGGAAGGA ATGACTGCTC 1140
TGATTTCTAT TTCTAAAAGA TCCAACAAGC CACTGGAGAG AGAATGACTG AGGGTGGAAA 1200
AACAGTCTGG TGAGACAGAA ACTGAAGGAG GAAACCAAAT GGCTCTGCTG TTTCTGAGTC 1260
CACAGGGCCT GGACACAGAA CCCCGCTACT CAGTCAAACT CTTACTCTAG GAGTTGCTGG 1320
GAGGGCATGT GGTAGCTCCG GGTGACTTCA AGTAAAGGAG CTTGTCCTCA AACATCTGGG 1380
TGGACCTCCT GTCAATAGCT GAAGGCCTTG AGAACCACAC GGAAACTTCC CTGAGGAAGG 1440
AGAGATTCCT CCCATGGACT CAGTGTCAGC TCCAGCCTGA GAGTTTCCAG CCTCCCGCCT 1500
GCCCTGGATT TCAGACTTGC CTAACCAGCA CCCCCACAGT TGCATAAGCC AGTTCCTCGC 1560
CATATATGAT GCAGCCACAT TAAGCATGAA ACATCTGTTT AGCATCCAAA TGTGCCAAAG 1620
AAAAAGATTT ACACTGATCA GAATTTGTTG GCATTTGATG CTGGAGCTGA GTGTGGGGGC 1680
TGCTCTGGAG ATGGGTCCAG CCCAGGGCAG TGCCCATAGT GAGATACCCA AGAAAGGAGG 1740
CCAGCGTGGT TGGAGGAGAC CTGGGAGGGA GCTGGCTCAG GCGAAAGGAG GAGGAAGCAC 1800
TGGTGCTGGG GGCAGGGGAA CTTTGACCCC AGTGTATCCG AGTGTCAGGG GAGGCAGGGG 1860
GTGGCAGAAG GGGTGCTGGT ATCCGAAGGG CAGGAGTGGA CTGATGGGGG ATGTGTGCTG 1920
TCAATGTTTC CTGAGATGGA GCAGCTGTTC CCAGCCACGG TGCAGCTGCA TAGGACAGCC 1980
CAGAAGAGGC AGAGCTGAGT GACACCAGGG CCAGCTTTGC CAGATAAGCG CAATAGTGGG 2040
CAAGCAGTGA GAACATGAAG GGTGTTCCTA ACAGAGTGGC TCTAACACGG TGCTGCCATG 2100
GAAGTTTTCT AGGGAGGAAG GGGGCCAGCC GGGGTGAGGC ACAGGGGGCT GCTGTGCCAA 2160
TGGGCAGGAC CAGCTGTGCC AGGTCCGGGT GTGGGGCCAG CTTGCTGGGA TGTGGTCTTA 2220
GAACCAGTGA GAAGAAAAGT AGAAACATGC AGGCAAGGGG TTCCCAAAGG GACTTTTCAG 2280
AGGGGTGGCA AGGCCAAGGG GCTGGGCGGC CTGGAAGGGC CACCACCAGG ATTAGTTCAG 2340
GTTGCCCAGA AGCTAGCACC AGGTGGCTGA GGCCACAAAG AGAAGCTGAT GAGGGGCGAC 2400
AGGGGCAGCC AGGGCATTTC CTTTCTGAAC TGTCCCCACT CAGATGAAAG CACCATGACT 2460
GACACACATC TGTGCACAAG GCGAGTAGCC ATGGAGCAGC 2500
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