| Tag | Content |
|---|
EnhancerAtlas ID | HS127-19960 |
Organism | Homo sapiens |
Tissue/cell | Macrophage |
Coordinate | chr21:39676730-39684020 |
TF binding sites/motifs | | TF | JASPAR ID | Coordinate | Motif Sequence | Strand | -Log10(p-value) |
| EWSR1-FLI1 | MA0149.1 | chr21:39683590-39683608 | GGAAGAAGGGAAGCAAGA | + | 6.44 | | IRF1 | MA0050.2 | chr21:39677016-39677037 | AAAGAAAAAGAAAAAGAAAAG | - | 6.02 | | IRF1 | MA0050.2 | chr21:39677010-39677031 | AAAAAAAAAGAAAAAGAAAAA | - | 6.09 | | MEF2C | MA0497.1 | chr21:39679693-39679708 | TTTTATTTTTAGTAC | - | 6.09 | | Pou2f3 | MA0627.1 | chr21:39678357-39678373 | CTTTATGCAAATTTAC | + | 6.23 | | STAT3 | MA0144.2 | chr21:39680735-39680746 | CTTCCCAGAAA | - | 6.02 | | TBX20 | MA0689.1 | chr21:39682170-39682181 | CTTCACACCTT | - | 6.32 | | TBX21 | MA0690.1 | chr21:39682171-39682181 | TTCACACCTT | - | 6.02 | | TCF7L2 | MA0523.1 | chr21:39678419-39678433 | GAAGTTCAAAGGGA | + | 6.42 |
|
| | Number of super-enhancer constituents: 17 | ID | Coordinate | Tissue/cell |
| SE_09241 | chr21:39677379-39679743 | CD14 | | SE_09241 | chr21:39679789-39681054 | CD14 | | SE_09241 | chr21:39681252-39684328 | CD14 | | SE_37197 | chr21:39677526-39681182 | HSMMtube | | SE_37197 | chr21:39681951-39684199 | HSMMtube | | SE_44178 | chr21:39677342-39681954 | NHDF-Ad | | SE_44178 | chr21:39681981-39683232 | NHDF-Ad | | SE_45623 | chr21:39677231-39681116 | Osteoblasts | | SE_45623 | chr21:39681134-39684721 | Osteoblasts | | SE_51700 | chr21:39677655-39680826 | Skeletal_Muscle_Myoblast | | SE_51700 | chr21:39682143-39683245 | Skeletal_Muscle_Myoblast | | SE_55658 | chr21:39676902-39681124 | u87 | | SE_55658 | chr21:39681294-39685018 | u87 | | SE_63489 | chr21:39677643-39680951 | HSMM | | SE_63489 | chr21:39682071-39683265 | HSMM | | SE_67472 | chr21:39676902-39681124 | u87 | | SE_67472 | chr21:39681294-39685018 | u87 |
|
| | Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder | | Number of disease enhancers: 8 | Chromosome | Start | End |
| chr21 | 39679926 | 39680725 | | chr21 | 39678061 | 39679254 | | chr21 | 39680731 | 39680904 | | chr21 | 39682405 | 39682794 | | chr21 | 39683029 | 39683113 | | chr21 | 39683665 | 39683952 | | chr21 | 39682559 | 39682791 | | chr21 | 39679705 | 39679828 |
|
| | Number: 3 | ID | Chromosome | Start | End |
| GH21I038305 | chr21 | 39677661 | 39681063 | | GH21I038310 | chr21 | 39682123 | 39683622 | | GH21I038311 | chr21 | 39683665 | 39683952 |
|
Enhancer Sequence | GGGACTACAG GCGCTCGCCA CCATGCCCGG CTAATTTTGT TTTTGTGTTT TTAGTAGAGA 60
CGGGGTTTCA CCGTGTTAAC CAGGATGGTC TCGATCTCAT GACCTCGTGA TCTGCCCGCC 120
TACAAGCCAG GTGTGGTGGT GCGTGCCTGT AATCCCAGCT ACTCAGGAGA CTGAGGCAGG 180
AGATTCGCTT GAACCCGGGA GGTGGACGTT GCAGTGAGCT AAGATCGCGC CACTGCACTC 240
CAGCCTGGGC AACAAAAGTA AAACTCCGTC TCAAAAAAAA AAAAAAAAAG AAAAAGAAAA 300
AGAAAAGAAA AGAAAATAAA CGTGGCAAAA CTAGACCTTC AGACACTTCA CTTCACTTAA 360
CCCTATGGCC CTCCTTATCT TGCACCCAAT TTCTTTTCAA CATCATACAT GCTTGGTTGA 420
CTGTTTCTTC ATATTTGCTG TTCATTCTAT AAAGTCAAAT AGATTGGTGG GTTAAAAAAT 480
AATCAATTCA AATTCAAATT AGGAATTTAT GGACATTCAG ATATCCACAT ATTTGAGGGC 540
AGGAATTTTT ACTTTTCAAT TGGTATGTTG GCAGTGTGTA AAAATAGAAG ACCAAGAGAA 600
GGCGGTTGAT TGGAGTTGAT ACTTAATAGC TAATAAAAAT TACAAGAAAG GATGGTGGAA 660
GTCAAAGGAC AGAACTGATA CACGAGTATA AAAGCCAACG ATGTCATATA TGTAGGCAAA 720
GTCTTTGTAA TCTGAATATA ATGCCAGAGA GCTAGGGCTG CCAGGCACTC TGTATGTGCA 780
GAATATGTCC TATATGGAGT AATTTTTTAT TTGTGTAGAC TTTTTTAGGA TACCTTAAAT 840
GTCTTACATG CAACCTTTTT TTCCCCATAT ATTACAAAAT TGCCTTGGAA ATTAGACAAA 900
TCTTCAAACT TAACTGAAAC TCCTGTCCTG AATAGTTATT TGCCAAATCT GACAAATTTA 960
CAAAGAGTGT TCACATAATC CCAAACTATG CCCATTTCTA CAAGAGAAAT ACATGCCTCT 1020
TTATTTGGAG TTTATGATAT TCATACAACT AGTAGTAGAG TCAGGGAGTA TTCCAGAAAC 1080
ATATTTCCCT GGCTTGCCCA ATTATCAAGG GAAAATTTCA GCTGAACACG GGGAACCCAG 1140
TCTTTGACAC TCCTGTGTGC AGTGTGGAGC AGCGTGCACT GTCTGAGTCT CCATAGTGAG 1200
GAATGGTCTT CCCTGGGGCA TCACCCTAGA AGGATGGGCT CAAAGTCGCC CTCCACGTGG 1260
GTGCACAGGA GCCCAGATTC TCAAGCCCCA GTTGCAGAAT TAGGCTGATG GTTTTACAAA 1320
AGAGTCCTCC TAAAAGTCCA TCACTAAGTT TTGTTTGGTT AGCAACCCTT GCCACATGAT 1380
GTAGTACTTA GCTATAATTT TATTTTTATT CAAGGCCAAA TCTTATCTGG TGTCCATGCC 1440
TTCCCACCTA CTTAAAATTT CAAATTTCAC CCTCAAAAAT ATTTCAGTAA ATAAAAGTTA 1500
GATCTACTCA AAATTAGACT CCAAGGGAAT TACTATAGTT GATTATAGAG TATCTATTTC 1560
CTTAAAAAAA AAAAACCATA AGTTGTTGAC TCTGAGCTAG GAAATGCGTG ATCTCTCAGC 1620
TGACTTACTT TATGCAAATT TACTTAATAT TATAGAAGAG TAAAGAGCTT CCAAGAAGGT 1680
GATTGGAGGG AAGTTCAAAG GGAAGATTTT TTTCATTCAC TGTAGTTTTA GCTGTATTCT 1740
TTCATCTGCA ATCAAATCTC AGGATTAAGG ATGTCGTATT ACATCAAATC ATTACAGGAA 1800
GTATGACTGT ATCAGCGGCT TTTTACAAAA ACAAACCTCC AGATCACAAA AGGAAGCTGT 1860
GTTTGTGTAC TGACACGAAG TGTTACGTAG CAGCCAGGAG AGGAAGGATA GCAGCCGACT 1920
TGGATCCATT TTTGAGGAAT TATTTCTGTA AGGTGTCATG GAATTGTAAG TTACAAAAAT 1980
AAGGCTTTTG TAAACAGAAT CTCCATTCCA GAAGGACGGA CTCCAAAATG CTACTTAATG 2040
AAATTCATGG GAATGTTATG GTGATGGAAA TCCCAAATGA CATGTAGATT TTATATGCAA 2100
ACAATCCCAC TGCTTGTAAC TCCTGGCAGT GTGTACTTAC CAAAATCTTG ATCACACTTA 2160
GGTCTCTTGC TATATATAGA ACCACATCTG ATCCTTATAC AGTGTTGCAA GATATATGTC 2220
CTTGCTTTCC CATGGTTCTT AAGTGAGTCT TAAGCTTGGA TTTGCTCCAG CAGAATGGTG 2280
GTTTGTGTTT CTCAAGGCTG AGCTACTATT TGGTGCATGT CGGAAATCTC ACACTAACTG 2340
TGGATACTCT GTCATCACTG AACCCAATCA TACAATGACC AGACAGCTTT AAATACCTAC 2400
TTTTGTATGC TATGAATTCA TCCGTTTACT TGTCAAATCC TTTATTTCCA TATGTGTCTC 2460
CATCACCTTT TTTTTCTCTC CGGATAAATG GAATTACTGT AACTTGTGAA ACAATGGCAA 2520
ACACTATAAA GCTAATTTTA CAGTCTTGAG TTTCTTTTTG TTTCACTGGA ATGGTAATGG 2580
TGTTACAGTG GTGCTCTGAC AGACAAAAAA TCTAATATGT CCTTAGAAAG TTCAGAGGGG 2640
AACTTATTTG AAATAACCTT TTCCAGTGAT GGCAATCACA ATAATGTGGG AATGACTAGG 2700
TCCTAAAAAC TTATCAAGGT GTTACTGTAT ATCAGTACGT AAAGAAATGT ATTTTGCTTC 2760
TTTCCAATCA CTGAATAGAA AATGAAATCC CTGCCTCATC GCTCCTTTTT TTTTTTTTTT 2820
TTAAGACAGA GTCTCACTCC ATCCCTCAGG CTGGAGAGCA GTGGCTCACT GCAATCTCCA 2880
CCTCCAGGAT TCAAATGATT CTCCTGCCTC AGCCTCCCAA GTAGCTGGGA TTACAGGTGT 2940
GTGCCACCAC GCCCAGCTAA TTTTTTTATT TTTAGTACAG ATAGGGTTTC ACCATGTTGG 3000
CCAAGTGGGT CTCAAACTCC TGACCTCAAG TGATCTGCCC GCCTTAGCCT CCTGAGTAGC 3060
TGTGATTACA GGCATGAGCC ACGGCGCCCA GCCTCATCTC TCTTTTTCTG CCTGATGCTC 3120
TCCTGCTCCA GAATGCTTAT TTCATTTTAG TCAATGATTA AAAATCAAGC AACCGTTTAA 3180
TAACAAACAT CCTTTCAGCA CTGCAACCCT TACCAAAGTG CCTTTTGTGC TATTGCTCCT 3240
TTACTTGGAT GGATTAAAAG AAAGAAAACA CTTAACTACA TAAGTCCTAC AGGCATTAGT 3300
ATGGGTGTCA CCCTAAAGCC GCACACCTAA TTAAAACCCA CGTAGCCAAG GAGTGCATCC 3360
AAATGGCAGT AGTTATCCTC CAAGCAGTTT CCTGGGAAAA CTACACACAC ATGCAACAAG 3420
ATAGTTGCCA CAGCTCTGAA CATTCCAGAG TGTCTCTCTT AGAGCCCTCT CCTTTGGAGC 3480
CTTGGCTCAT TCTTTGTAAC ATTCTCAGGG GTGGCCAAGC TTTGTTCTTG GAGGGAGCAT 3540
GTGACAGCTG GAAATAAACA AGGCTGATGC AGATAGTAGG AAGTCATCTT TGAGGATACT 3600
GTTTGAACAA AAAGGCAAAA TGTTTTCTAG AAAGTGCACA GTCATCTGAA ACACAGTCAT 3660
GAAGCTAGCC GGTGGGACAC ATTTTATTAA TTTTAATTTG CATGGAAGTT TTCAGACACA 3720
TGTTATTTTC TACCCCGTTA TCTCAAACGT CAATTGTCCT TCCAGGATGA CCTTGGCTGA 3780
GAACTGAGCT AACCACATCC AAGCCATAAG GCAGCATTGC TTTCACCACA CCATGTCCTT 3840
GGAGCAGAGA ATAAGGGAAT TTGTCATAGC AACATGGGAA GCTTTGGTTC TGGGCTGGAT 3900
ACGCAACATC CCGGCAGGCA TAATTTCCCT TCTCAGAAAT CCTGTCTTCA TAAATGTTAG 3960
ACAAACAACT TTTATGGTTT AATTTTTCAT GCAAAAGTCC ATATTCTTCC CAGAAACTCT 4020
TACATTGTTC AAGTGATTAT GTTCTAAATT AGTCTATTCC TTTACTGGAA TTTAACACTT 4080
GCATAATAAT CTTAGCTGAT AAGGTATTTG AGTGATCTAA ATGTGTTTTC ACCCGTCCTA 4140
AGGGCTGCTT TCTGCATCTT TCTTAGTTTG CCTCTATTGA GTCTGCCAGA AACTCTTACT 4200
CTTTTTAAGA TTTTGTTCAC GTTTTTATTT TATTTTTTTA TTTTTTGAGA CGAAGTATCC 4260
CTCTTGTTGC CCAGGCTGGA GTGCAGTGGC GCAATCCCAG CTCACCGCAA CCTCCGCCTC 4320
TTGGGTTCAA GCAATTCTCC AGCCACAGCC TCCTAAGTAG CTGGTATCAG AGGCTCCCAC 4380
CACCACACCC AGTTAATTTT TGTATTTTTA GTAGAGACGG GGTTTCGCCA TGTTGGTGAG 4440
GCTGGTCTCG AACACCTGAC CTCAGGTGAT ATGCCCACCT CAGCCTCCCA AAGTGCTGGG 4500
ATTACAGGTG TGAGCCACCA TGCCCAGCCC ACACATATTT TTAATTAACA AATAATAACT 4560
ATATATAGTT AGGGATTACA ATGTGATATT TTAATACACA TTTTAGAATA ATTATATCAA 4620
GCTAATGATA TATCCATCTC CTCACGTATT TTCTTTTTTG TAGTGAGAGC ATTTAAAACC 4680
CACTCTATTA GCAGTTGTAC TTTCTCTTGA CAGTGTACCT CTCTGTAAAC TCTGTTTAAC 4740
GTGCCCACTC AGCATGTGAT TTAAAGATCT GCAATGAATA AGTCCACTAT GACCAACAGA 4800
CTCACAGCCT CACAGCAGCC CAGAACAGTG TGCTTCTCCT TACCCCTACC CCCACAGTAA 4860
GTCTGGCTGA CCTGCTACAT GTTCAAATAT GTTGTGGCAT GTTCTATTGC CCGCGTGCCT 4920
CTTCTGCTCA TACAAGCCCC ACACCCCCCA AACACACAAG TCTCATGACA TCTGGTCACA 4980
TCTTAGATAT CCAGAGAGCA AGAAATATTC ATATTTGTAG GGCTCTGAAT GCTAAAAACA 5040
ACTTCAAATA TTCAATAGTC CATGTTATAC CCCATGAAAG GGTAGAGGAA GGACATATGC 5100
AGTTATCTAC ACTTTGCAGA AGACCCTGTA GCCCACTGAC ATCACTTCCA GAGTGGCCCA 5160
GTGAGCCATT GGTGGCAATC TGGGTCTTTT CCTTCTTTTC TTTTCTTTTT TTTTTTGTTG 5220
AGACAGGATC TCACTCTGTC ACCTGGGCTG GAGTGCAGTG GCGTGATCAC GGGTCACTGT 5280
AACAACTTCC CAGGCTCAAG CAATCCTCCC GCTTCATCCT CCTGAGTAAC TGGGACTGCA 5340
GGTGTGCGCC ACGATACCCG GATAATTTTT TAATTTTTTT GTAGAGATGA GGTCTCAGCT 5400
TATTGCTCAG GCTGATGGCG AACTCCTGAG CTCAAGCGAT CTTCACACCT TGGCCTCCCA 5460
AAGTGTTGGG ATTACAGGTG TGAGCCACTA TGCTCAGTCT GGATTTTTTC CTTCTGGCCT 5520
AGTGTTTTAT CTCCAAAATT TACAACATGG AAATCTCATG GTGGAGCAGA TTTCCATGTG 5580
AGATGGATCA AAATTAGGGC AAAAGTGATA GCAGAATAGA TAACCCAGGT GAAAGCATGA 5640
GACTGGGAGT CTGGATAAAT TGCCTAAAGG CCTAACATGC TTCAAAAGGT CTGTTATTTA 5700
GAGGCTGGCA ACATGAGATA AATATCCCGA AGGTAGAGAA GATATGAAGT GATCAATTGA 5760
AAAGGAAAAG GCAGAGGAGT AAGAATGCCA TTCATCAAGA CAGAAACAGA ATCCACATCC 5820
CTGCTGTTCA TCTAAGCAGA GACAAACGGT TGACCAAAGA CTAGACATGG GGTGACTAAG 5880
ATTAAGAAAT CCTACAGAAA AGTCAAGATG AACAAGCATT CAGTTCTCAA GTCCTCACAT 5940
TCATTATGAT TGCATCATAT GAGGCTCAGA AAAGTTGAGT AATTTGTCCA GTTACCCATC 6000
TACCAAGGCG TAAAGCCAGG AGTGGCCAAC ATAAAAGCCT GGCTTCCTCT CCATGTTTTG 6060
TCCTGCCTCC CAGGTGGGCC ATTACAGGGT GCATCCAAAA AAGCATAGGT GATTTGGTGG 6120
TTGATGCTCT TGGAGCCAAA GCAGCATTTG CTTTGTGCTC AAGTGTTTCC ATCAAGTGAA 6180
AACAAAGCCA TGGTTGAATT GCGGTGTCAC CACAGACGAC TTGCGGGCGT TGAATTCATG 6240
CAATGCAAAT AATAAGGGAT TGTGCCAGTG TGCCTCCCAT TGTGAATAGA GCAGTGAGCT 6300
TTCAACTGAA TGTTTTGCTG AGTTCTAAAA ACCTGATTTG TAAGGATTTA TACTGGGCTT 6360
CTCAGAGAGG CTTTAGGGTA GGTAATTATT TTAAGGTCTT GGCTGATTGA GTCAAGCGGC 6420
AAAGAGAGCT TTGTAGAGAC AAGCAAACAC TGCAGAATCA GTGCAGCTGG CTGGAATCCG 6480
ATACTGAGCT TACAGGGCCT AAAGGGAGCA GGTGAGTGGT CCCAGCACAA GCAGTCACTG 6540
CAATTACAGT GACCAGGCCC GGGGAAGGAA GGCTCAAGAC CCAGACACCA AGAAAAGCTA 6600
GAAACACAGG GCAAGAGAAC AAGGGGTCTT AGAAGCTGAC TCTAGAAAGA TGTTCTGACA 6660
GATTGCTCTT GGCACTAGGG AAGACCTGCC TACAAATCTC TCCATTTCAC AAGCAGATAA 6720
ATAAAGAGGG GCAAATAGGA GAGGAGTGGA GTATGAACCC ACAACACATG ACGGAGATCA 6780
AGGAAGTAGA GCTTCAGGAG CAGAGACCCA GACCCAGGGC CTTCAAATCA AGGGCAGGAC 6840
TCTGTCCTTA ATAGGAGTCA GGAAGAAGGG AAGCAAGACA AAAATCCTAC TGCAGGGACA 6900
GAAAAATGAA GGCTGGAACT CAAGTGCAAA GAGGCTGGCC AACACAGGAA AGGAACTGGG 6960
TAAAATACTG GGGCTTCCTC ATTGGAAAGA AGGATTTGTG GCAAGCTGGA CCTGGACAAG 7020
GTACACTTGT TAAGGAGTCA ATGGCTCGTA ACATCTTCAT CTCTCCTCAG TAGGAATCAG 7080
AGCCGGAAAC CACAATTTCT ATTTCAGTGC TTCCCAGGGC AAGAATTGGC AGCCAGAAGG 7140
CAAGCACATC ATCACAGCCT GAAGTGCATA TTTCATCATC AGATGAAGCG GTTTCTCGCA 7200
TCATTTATTA TTTACCCAGT CACTTTAACA ACCACCTGAT CTCTGAGACA GGTCCGTGGA 7260
GTGTTGTGGT CTCCACATTA ATATTTATTT 7290
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