| Tag | Content |
|---|
EnhancerAtlas ID | HS127-19926 |
Organism | Homo sapiens |
Tissue/cell | Macrophage |
Coordinate | chr21:37448690-37452230 |
TF binding sites/motifs | | TF | JASPAR ID | Coordinate | Motif Sequence | Strand | -Log10(p-value) |
| HSF1 | MA0486.2 | chr21:37450122-37450135 | TTCTGGAACATTC | + | 6.67 | | IRF1 | MA0050.2 | chr21:37451431-37451452 | AAAGTGAAACAGAAACCCGAA | - | 6.83 | | IRF1 | MA0050.2 | chr21:37449746-37449767 | CTTAAGTTTCAGTTTCTCTTA | + | 7.27 | | IRF2 | MA0051.1 | chr21:37451429-37451447 | GGAAAGTGAAACAGAAAC | + | 7.17 | | IRF9 | MA0653.1 | chr21:37449750-37449765 | AGTTTCAGTTTCTCT | - | 6.28 | | KLF4 | MA0039.3 | chr21:37451259-37451270 | CCACACCCTGC | + | 6.62 | | NFIC | MA0161.2 | chr21:37449882-37449893 | TACTTGGCACA | + | 6.32 | | Nr2f6(var.2) | MA0728.1 | chr21:37448834-37448849 | GAGGTCAGGAGTTCA | + | 6.22 | | RARA | MA0729.1 | chr21:37448834-37448852 | GAGGTCAGGAGTTCAAGC | + | 6.52 | | SOX10 | MA0442.2 | chr21:37449485-37449496 | TCCTTTGTTTT | - | 6.32 | | Sox3 | MA0514.1 | chr21:37449486-37449496 | CCTTTGTTTT | + | 6.02 | | Sox3 | MA0514.1 | chr21:37451867-37451877 | CCTTTGTTTT | + | 6.02 | | Sox3 | MA0514.1 | chr21:37451900-37451910 | CCTTTGTTTT | + | 6.02 |
|
| | Number of super-enhancer constituents: 3 | ID | Coordinate | Tissue/cell |
| SE_05692 | chr21:37446663-37449329 | Brain_Cingulate_Gyrus | | SE_05692 | chr21:37451208-37453531 | Brain_Cingulate_Gyrus | | SE_07229 | chr21:37441136-37449886 | Brain_Hippocampus_Middle_150 |
|
| | Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder | | Number of disease enhancers: 3 | Chromosome | Start | End |
| chr21 | 37452142 | 37452201 | | chr21 | 37450069 | 37450589 | | chr21 | 37450927 | 37451130 |
|
| | Number: 2 | ID | Chromosome | Start | End |
| GH21I036076 | chr21 | 37448715 | 37450296 | | GH21I036078 | chr21 | 37450562 | 37452513 |
|
Enhancer Sequence | AAAAAAAATG AAAGACACAG ATTACCAATG TCAGGAATGA GAAGTAGCAT CATTATGATT 60
AATAAGAAGA TAATAAGGGG TTGGGCACAG TGGCTCACAC CTAAAATCCC AGCTCTTTGG 120
GAAGCCGAGG CAGGTGGATC ACCTGAGGTC AGGAGTTCAA GCCCAGCGGG CCAACAGGGT 180
GAAACCCCAT CTCTACTAGA AATACAAAAA CTAGCCAGAC ATTGTGGCAG ACACCTGTAA 240
TCCCAGCTAC TCTGGAGGCT GAGGCAGGAG AATCGCTTGA ACCCAGGTGG AGATTGCAGT 300
GAACCGAGAT CATGCCACTG CACTCCAGCC TGGGCAACAG AGTAAGACTG TCTAAAAAAA 360
AAAAGAGCAT TTTACTAACA ACCTCAAATC ATTGGAATTA ACAACTTACA TAAAATGTAC 420
ACATTTATTA ATATTTAGAA AAACACTAAG CTCACTGAAG AAGAAATGGA AAACCTGAAT 480
AGCTCTATGT CTGTAAAGTG AAGTTTCAAA TACTCTTTGG AAAGAAAGAA AGATTGGTTG 540
GGGCATAAAG GGAACCACAC CCAGCAGGTG CCCAGCTATT AACTTGACTT TGATAGAGAA 600
AGTGGACTCG GTGGCAGGGC ACAGGCAGTT CAGCCAGATC TGCTTGAGTA AAGCAGAGTC 660
ATGATGAGAT GGTGGCTCTC TGCTAATCTC AGAGTCGCTA ATCAAACACA CTCAGATCAA 720
ACACGTGGGT TACAGTGAAG AAGACGAATG AAGGAATCCA ATTGCCCGTC TATACCTTGA 780
CACACCTTTG ACAATTCCTT TGTTTTGTGG GTACACATTT CATGGGGAGA TGCCATATAT 840
TTTACATATT AACTGTGACT TTGGATAAAA CAAAAATGCA GACACTTTTA GCAAACGGGT 900
TATGTAACAA TTAGATAAAA CATTCTAATA AATGGCTTAC GGCATAGTAG GAGCTTCATA 960
AACATTCTCT CTCATTTGAG GGCATATTAG GAACCACACA GAGATTGCCT GCCCATGCCT 1020
GGAAGTCTAA TTACAGGACA TCTTTTTTCT CTAATTCTTA AGTTTCAGTT TCTCTTAAGA 1080
AAGGGGATGT ATGTCCTGAG AAGCACTTAG TGTGTAAATA ATTTCATTGC ATCTTAAGAT 1140
AAAGCAAACA TCTGCATTTT GCAGTGGGTG ATGGGTGCAC ATCCAAGAAA ATTACTTGGC 1200
ACATGTTTTC CTCCCTTTGG GATTCTCCCA AAATAGTTTT AATTCAACTG TCACCTGTCT 1260
CAGGCCCCCT ACTGACCCAT CACCATCCAG TTTTGCTTTC AGAGAGCCCG ACCTCTTAGC 1320
CCTGCAAACC ATTGCTTGGC TCTGTTAGGA TCAAAAGAGG GATGTGTCTT GGCATGACCC 1380
AATACACAGC TCATGGAAAG GGTAGACCCA GGAGTGGGGG CATTAGGAAA CTTTCTGGAA 1440
CATTCAGCCC CTCGAGTTGC AGCACTGGAA TGCAGAACTT AGCTCTGCTG TACAGCCCAG 1500
AGCAACCATG CCGGCCTGCA GCCATAAGGC ACCTTCAGGC TGCAACAATT CCGAGAATTG 1560
ACGTCTCTGT ACACGCAGGT CCCAATACCA CTTATAATGT GTACGAGGTG TTAGTCTCAG 1620
ATAAACAGGA CTGGGCACTT TGGCTGCAAA CAAAGCAGCA TCTGGTGGGA CACACGGAGG 1680
CACAAGGAGG TACAAGAGGA GTTGTTCATG ACACGGGGTC AGAATCCATG CCTTCCATTA 1740
GCTGGGCTAC TTACTCGGAT CTCCATAATC CCAATATAGG TGAGAAGGTG TCTATACCCT 1800
GTGAAGTATA ATTTTGGCAG AACAAGGTAC ATTTCTTAGG ATATGGACTA TCCCAGGAAG 1860
TCCATCCCTC ACAAGGATTT ACCATTCGGA ACTGCCCAGT CCTGACACTA AAAGACAACA 1920
CAGGAGATTT AGGGTCACAC TAGCTATTGC AGAAAGTCAG TCCCTAACTT TTCTGTAATC 1980
ACCACAATTC TATAACTTTC AGTCATCTAT GCCAGAATTC CCATTTTTGG GAACAGTAAT 2040
AGATTGAAGG CTGGCTGCCA AGAAGATATG TCCATGTGTC AGAATCTATG AATATTTTCT 2100
TTGGAAGAAA GATTTTTGCA AATGTAATTA AGGATTTCAA GCTGAGCTCA TCCTGGATTA 2160
TCTGGGTGGG CCCTAAATCA ATGACAAGTG TCTTTTTACA AAACAGAGAG ACAAGGCAGG 2220
CATATGAAGA CAGGTTGATT AGAGGGATGT GGCCGTAGCC CCAAGCCAAG GAAAGCCTGC 2280
AGCCCACAAA AGCTGGAAGA GTCAAGGAAA GATTTCTCTC TAGAGACTTT GGAGGGAATG 2340
CAGCTATACT GACAGCTTGA TTTCAGAATT CTGGCCTCCA GAACTATGAG AGTAAATCTC 2400
CGTTGTAAGT CACCAAGTTT GGGGTTATCT GTTTCATTTT GTTTTGTTTT TTGAGACGAA 2460
GTCTCGCTCT GTTGCCCAGG CTGGAGTGCA GTGATGCGAT CTCGGCTCAC TGAAACCTCT 2520
GCCTCCCGGG TTCAAGCTCA GGAGCAGCTG GGATTACGGA CACATACCAC CACACCCTGC 2580
TAAGTTTTGT ATTTTTGTAA AGACGGGGTT TCACCATGTT GGCCAGGCTG GTCTCAAACT 2640
CCAGACCTCA AGTGATCCAC CTGCCTTGGC CTCCCAGAGT GCTGGGATTA CAGGCATGAG 2700
CCACCACGCC CGCCCGGATC ATGTGTTATG GCAGCCCTAG GAAAGTGAAA CAGAAACCCG 2760
AACATAAGCA GATATCCTGT GACTGAAATT AACCCTCCAA CAACTTCCCA CTCTGGCCTT 2820
AGCTAACTAT GAACCTCTCT GCTCACTCAT ACAGAAGGGC TTCCAATTTT TACCCAGTTC 2880
TCTGGAGCCT AGAAGCAAAA AGCTATGACA ACCTTTTTCT TGATCCGGCA GCAGACTCAT 2940
CCACCTTGTC TCAGAGCAGC AGTGGCAGCA GCAGCCGCGT GCCTGAAGCC CTCTGTCGCC 3000
TTACCCCTGG AGCCTCCTTT AACATAGGGC CCTCCGGCTG CACAGTTTTT GCTGCTCACT 3060
GAAAATAGTC AACATTTCTG AGAAAACTGA TTCACCTCCC GAGACATTAG AACGAGATCT 3120
CAAATGCCTA GAACAACTGA CTGCTGTACG TGTCTTCACG TTTTTGTTCC TTACATACCT 3180
TTGTTTTTAG TTACTTTCGT TCCTTATTTA CCTTTGTTTT TTTTTGTTTT TTTTTTTTCC 3240
CTTTCTCTGC TGGTTTAAGG TTCTGGATTG CAAATAGCTA CTTGTTATCT CCTAACTATG 3300
TCACCCATGT GGGCCCCTGT TCCTAATACT GCCTTTGTAC TACCCCTCGT GACTCCATGG 3360
CTTAAACATA ATTTAACCAA CCATTGGAAT TATGTCCACA TTTGATATGT TTTGGATCTA 3420
TGTCCCCACC CAAATCTCAT GTCAATAATC CTCCCAGTGC TGGAGGTGGG TCCTCGTGGG 3480
ACTGATTGGA TCATGGGGGC GGGTTCCCAT GAATGGGTTA GCGCCATCCC CCCAGTGTTG 3540
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