| Tag | Content |
|---|
EnhancerAtlas ID | HS127-02897 |
Organism | Homo sapiens |
Tissue/cell | Macrophage |
Coordinate | chr1:224010120-224027040 |
TF binding sites/motifs | | TF | JASPAR ID | Coordinate | Motif Sequence | Strand | -Log10(p-value) |
| Arid3b | MA0601.1 | chr1:224022191-224022202 | ATATTAATTAT | + | 6.02 | | Arid3b | MA0601.1 | chr1:224017785-224017796 | ATATTAATTAA | + | 6.62 | | BARHL2 | MA0635.1 | chr1:224013226-224013236 | GCTAAACGGT | + | 6.02 | | Crx | MA0467.1 | chr1:224027012-224027023 | AAGGGGATTAG | + | 6.32 | | DMRT3 | MA0610.1 | chr1:224024182-224024193 | AATGTATCAAT | + | 6.62 | | EWSR1-FLI1 | MA0149.1 | chr1:224023315-224023333 | ATTTCCTTCCTACCTCCC | - | 6.27 | | Foxq1 | MA0040.1 | chr1:224017690-224017701 | AATAAACAATA | - | 6.62 | | Gata1 | MA0035.3 | chr1:224026965-224026976 | TCCTTATCTGT | + | 6.14 | | IRF1 | MA0050.2 | chr1:224019102-224019123 | AAAAAAAAAAAAAAAGTAAAA | - | 6.16 | | JUN(var.2) | MA0489.1 | chr1:224019681-224019695 | TAAGAATGACTCAT | + | 6 | | KLF16 | MA0741.1 | chr1:224025619-224025630 | GCCCCGCCCCC | + | 6.02 | | KLF5 | MA0599.1 | chr1:224025619-224025629 | GCCCCGCCCC | + | 6.02 | | LMX1B | MA0703.2 | chr1:224017788-224017799 | TTAATTAAAAC | - | 6.14 | | MSC | MA0665.1 | chr1:224017449-224017459 | AACAGCTGTT | + | 6.02 | | MSC | MA0665.1 | chr1:224017449-224017459 | AACAGCTGTT | - | 6.02 | | MYF6 | MA0667.1 | chr1:224017449-224017459 | AACAGCTGTT | + | 6.02 | | MYF6 | MA0667.1 | chr1:224017449-224017459 | AACAGCTGTT | - | 6.02 | | NFIA | MA0670.1 | chr1:224013118-224013128 | GGTGCCAAGT | + | 6.02 | | Nkx2-5(var.2) | MA0503.1 | chr1:224025264-224025275 | CTTGAGTGCCT | - | 6.14 | | POU2F2 | MA0507.1 | chr1:224022262-224022275 | TATATTTGCATAT | + | 6.3 | | POU2F2 | MA0507.1 | chr1:224016478-224016491 | ATATGCAAATGCA | - | 7.22 | | RREB1 | MA0073.1 | chr1:224012721-224012741 | ACACCAAACACACACACACA | + | 6.41 | | Sox6 | MA0515.1 | chr1:224019596-224019606 | AAAACAATGG | - | 6.02 | | TBX20 | MA0689.1 | chr1:224010464-224010475 | TTTCACACCTA | - | 6.14 | | TBX2 | MA0688.1 | chr1:224010464-224010475 | TTTCACACCTA | - | 6.32 | | TCF3 | MA0522.2 | chr1:224011745-224011755 | AGCAGGTGTT | - | 6.02 | | TCF7L2 | MA0523.1 | chr1:224017623-224017637 | TTCCTTTGAACTTA | - | 6.2 | | TCF7L2 | MA0523.1 | chr1:224011528-224011542 | TTGCTTTGAAGTTT | - | 6 | | ZNF263 | MA0528.1 | chr1:224014722-224014743 | GAAGGAGGAACAGGTTGGGAA | + | 6.05 | | ZNF263 | MA0528.1 | chr1:224022664-224022685 | CCTCCCTGGTTTTCCTCCTCC | - | 6.56 |
|
| | Number of super-enhancer constituents: 5 | ID | Coordinate | Tissue/cell |
| SE_09755 | chr1:224012136-224016789 | CD14 | | SE_09755 | chr1:224018879-224024980 | CD14 | | SE_18793 | chr1:224018897-224025157 | CD4p_CD25-_Il17-_PMAstim_Th | | SE_19882 | chr1:224019081-224022196 | CD4p_CD25-_Il17p_PMAstim_Th17 | | SE_19882 | chr1:224022236-224024239 | CD4p_CD25-_Il17p_PMAstim_Th17 |
|
| | Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder | | Number of disease enhancers: 14 | Chromosome | Start | End |
| chr1 | 224019418 | 224020617 | | chr1 | 224022197 | 224022347 | | chr1 | 224022569 | 224022929 | | chr1 | 224026427 | 224026662 | | chr1 | 224014874 | 224015267 | | chr1 | 224019430 | 224020596 | | chr1 | 224013042 | 224013149 | | chr1 | 224023477 | 224023773 | | chr1 | 224023666 | 224023784 | | chr1 | 224014800 | 224015435 | | chr1 | 224019337 | 224020776 | | chr1 | 224023600 | 224023624 | | chr1 | 224024367 | 224024631 | | chr1 | 224026109 | 224026396 |
|
| | Number: 5 | ID | Chromosome | Start | End |
| GH01I223823 | chr1 | 224010903 | 224011102 | | GH01I223825 | chr1 | 224012704 | 224015501 | | GH01I223831 | chr1 | 224018704 | 224025501 | | GH01I223838 | chr1 | 224025903 | 224026302 | | GH01I223829 | chr1 | 224017095 | 224018531 |
|
Enhancer Sequence | ACTTTGGGAG GCCAAGGCGG GAAGATCATG TGAGTCCAGG AGTTTAAGAC CAGTCTGGGC 60
AACGAAGCAA CACTCCGTTT CTACCAAAAA TTAAAAGAAA ATCAGCCAGA CATGGTGGCA 120
CATGCCTGTG GTCCCTGCTA CTTGGAAGGC TGAGTGGGGA AGACTGCTTG AGTCCAGGAG 180
GTCGCAGCTG TAGTGAGAAG TGACTGCACC ACTGCACTCC AGCCTGGGTG AGACCCTGAC 240
TCAAAAAAAA AAAAACAACA AAAAAACCTA ACAATCTTGA CAATCTTTCT CCTAGTAAAA 300
AAAGACACTG TATCTTAGAA ACACTGCTAC TAAAGAATTA AATTTTTCAC ACCTATTAAA 360
TTACAAAAAA AAAAATCTTG TTAATTTCCA ATGCTGAAGA AACGAAGTGA AACAGGAAAC 420
AAGTTTTCGA CAGTGATGCA AATTAGTAAG GCTCTATGTT TATTCAATTC AATGAGTAAC 480
TCCATGCAAG TCAGTATGTA TCAGGATTAA AAAATAATAA TTTGAAAGCG TTACCTCACA 540
GTGAGAATAC ATCCTGTGAA AATAATTCCA ATCAAAGAAA GAGAATGCAT AACCTATGGA 600
ACATAAACTT GAGGGACAAG TTTAGTCTTT TAAAATCATT AATGAAACTA TGCTAAGCAC 660
TGGGAAAAGT TTGGGTTTTA AGACTGCAAA AAAGCAGAAT AAGTAGGATA TACCCTATGA 720
CCACAATGAC AGGAGGACAT CACACAGCAA TTGGAGGGCC TACCAACAGT CACACAACTC 780
CCCTTCCAAC TTAAATGTCT CTGCCCATTA CCCCCAAGTG GAGAAAGCTG CATTAAGATG 840
TTGCTTGGGA AAAGGCAGCA CCGGATTAGG GATGATGATG GAAACTGGCT AAGACATCAG 900
ACTCGGTGCC TCAAGAATTG GTCAGAGAAA GAGGAGATAT ACATGAGAGA AAGAGCGGAC 960
CCTTGCACTC AAGCCAGTCC AAGCCTCCAC ATTCTGCAAC CAAAGCTGTT AACTCACATG 1020
AACAGGTATA ACAGAGGGTA ATCCAGAAAA ATTAAAATAG TGAACACTGT TGAAACAATT 1080
TTTTAATGGA AAAATAAAAA AACACTGTAG ACTTTCCCAG TATGAGCTCA AAAGCTCTCA 1140
AGCTAATTAT CTCAGGCTTT TCACATTTTG ACTACATAAA GGTACACAGT TCTAGAGTTC 1200
AACTTAGCCA ACAAGGCAGC ACTCAAAATT ATTACACAAA AATCATAAAG CCTTGACTAA 1260
ATCATTGAAA AAATAAAACG ATTAACAAAG CACAGAAGTA CACTCGTCTG CTGCTCCCAA 1320
AGTATACAGC ATATTCAGTG ATGGAGACAA ATAATGTACA CTTTAGCATT AAATACTCCC 1380
TCTCCATACT CCCTACCGAT GCAAAAACTT GCTTTGAAGT TTATCACTTT GAAAATAGTA 1440
ACTTTTCATT GTAAATATGA AGCTTAGAGG TGTTAAGTTA CAGAAATACT GGAAATACAG 1500
AGTATATGCT AAACACACAC CTTATCAACA AATAAAAGCC TATTATGTAA GATAGCACCT 1560
TACCTCTGTA AACTTCATCT TTCAGACACA TTATCTCAGA AACTTACATC AACTCTCAGA 1620
TAAACAGCAG GTGTTATTTT CTCTTTATAA ATGAAGAAAA AGACTCAGAT AAGTGATCTA 1680
TTTGCCTACT GAAATGAGAA AGGTACAATT CTGTTTTTCT GATCTATCCT CTATTCTTTA 1740
AGCTGTCCTT TATAGAAAGA AAATACTAGG AAATGCTCCA TTTAACCACA GTTACCCACA 1800
CTTTAACAGA GATCTGATCT TTTACTTTCT GGAAAACCAA CAGCTTCATT TATTTAAAAG 1860
TACAATTAAA AATAAGAATG ATGACAGATG TGTTCTATTT ATGGTTACTT TTCCCACAGG 1920
TTTAACACTG GTATGAACAG TAAGTGTACG AGTTGACCCC GCTTCTACCT GTAATGTATG 1980
GAGATTAGCT CTGCGGTGAT TTTAGTAATT GTACTGCAGT CCGCGATGCT GGGCCAGCAA 2040
CACGCTATTT TTGTCGATTC CCAGGCAGGA GATCTAGTTC AAACTCCAGA TTTCTTCATA 2100
ATTAGTTAGA CTACCTTAGG CAAGTAATGT CACCTCTCTG AAACTCAGCA TCCTCATCTT 2160
CAAAATGAGT CTTTAAGTTC CCCAATAGCT ACACGTTTAC CTACGTAACA AACCTGCACA 2220
TCCTGCACCT GTATCCCAGA ACTTAAAATT AATTTTTAAA AAAAAAAGTT CCCTAAGAGC 2280
TACTATTTAG TAAATGTTTA CTAGGTACCA GAGTAAAAGT CAACATTTTT ACAGCAGCCT 2340
ACAAGGTCTG CTGTAGTCAT GATCTGGCCC CCATTTCCTT CTAATCCCCC CTCACTCTGT 2400
GCTCTATCAG CGTCCTCTTT GCTGTTCATC AAACACACCA GGCATGTTCC CAGGTGGGAG 2460
CCTCTGTACT TGCTGTTCCT CTATTTGGAA TGCGCTTCTT TGTATGCCAG TGTAACTCTC 2520
CCTTCCTCAT CTCCGTCACG CCTTTACTCA GATGTCACCC TCTCAGTGAA GCCTTACCTA 2580
GGAACCCTAC CTAGAATTCC AACACCAAAC ACACACACAC ACACACACAC ACACACCCTA 2640
GCCCATTCTT CTGCTTTATT TCCCTCCTTA GCACAGTCAC TAACATGTCA TATGTTATAT 2700
TTATTTAACT CATTTTTATT ATCTGCCTTT CCTACTAGAA AGTAAGCTCC ATACAGTCAA 2760
AGGTTTTGTC TTTGTTCAGT GTTGTAGACT CAGCGCCTAG AACTGTGCTT GGTGTGTAAC 2820
AAGTACACAC TAAGTATTAA ATCCTGCAAA TGTGATTGCA TTTTACAGAT GAAAACACTG 2880
AAGCACAGAG GGATTTAAGT AACTCACCCA GGTCACACAG CTATTAAGTG GCAAAACCAA 2940
GATTGAGCCC CTTCCTTGAG AGCATACAGG TAAAGACTCT CCTGAATCTG GACCACACGG 3000
TGCCAAGTGT GTCACTGCCT CTAGTTCTGT CTTTTAGAGC AACATTTTGC CCACAATCCA 3060
TCATCTCACC TGATTTATTT TCACGGTCAG TTTTGTTTCA GGTACTGCTA AACGGTATGG 3120
CATGTAGCGT GTAGCACAGC TATATACTCT CAAATGAGAG AGTGTGTTGT CCACTCATAT 3180
CTTCAGCTTA CATCCTGCTA CCATCATTCT ACCTCTGTTT CAACATTATT TTCATTCATT 3240
CAGTATTTAC AGATCATCTG CTATATGTCT CTGTTCTAAT GTAAAAATAA TCTTTACTAA 3300
ACAGGTAATA CTACAGACAG TACAAAATTC AAAGAGAGAG AAAGAAAGCT GTTAGAAGGA 3360
CACAGCCAGC CCACAGGAAG GAAGTCAAAA AAATAAACAC CACAACCTGG CTCCTTCCCT 3420
CTCATGTCCA CCCACTACTC CCCACTGGAC AAACCCAACT ACCTACCAGA TGGCAAGGGA 3480
AGCGGTTGAT GCAGTTTAGA GAAGTCAACC TCCTAAGGCA CAAAGCAGGG TGGAGGAAGG 3540
TGAAAAGTGA ATGCAGAGAG GCAAAAAAAA GACACTCAGC ACAGGAGCCC TCCTCTCCGT 3600
ACTATGCAGT CAGAGGACTC TTGAGCAACC GAGCAACCAT CTAAAGGAAG TGAGGACACA 3660
GCCCAGCTAA GGTCTGGGAG AAGAATGTGC CAACCAGAGG CAACACATTT AAAGCCCTTG 3720
AGAAGGAAAC AAGTTTGTCA CATTTGCACA AGAGGAAGGT CACTGCAGAC GAAGCAAGAG 3780
GAAAGGGTTA ATTCAAGGAG GCAAGCAAAA GCCAGATCAT GCATGTCTTT ATAGGCTGGA 3840
GGTTCCCAAA CTTTGGTGTG GACAGAGGGT CGTTATTAAA CACAGATTGC AGGGCTCCAC 3900
CCCAAGAATT CCAAAATCAA TAGATCTGGG TTGGAGACTG AAAATTCTGC ATTTCTAACA 3960
AGCCCTCAGG TGATGTTGAT ACTGCCGGTC TAGAAACCAC GTCCTGAGAA CCATCGTCTA 4020
AGGCTAGGGC AAGGACTGTG GATTTTAATC TAAAAGCCCA CTGGAGGCAA ATCATTAAAG 4080
TCAGAAAGTA GATCACTGGG TGTCAGGAGC TGCGGGAAGG GGAAATGGGA AGTGACTGCT 4140
AATAGGTACA GGGCTACTTT TTGGGGTGAT GAAAATATTC TGGAATTAGT GGTGATAGTT 4200
ACACAACATT GTGAATACAT TAAATACCAC TGAATTACGT ATTTCAAAAT GATTAGTTTT 4260
ATGGTATGTG AATTATATCT CAATTTTCAA AAGTAAGAGG TTACTGGAGG ATTTTGAACG 4320
GGGTAGCTAT TTATGCCCTT AAAAAAAATC ACTATATGAA CAAACTACAG GAGGACTGGC 4380
ATGAAAGTCC AATTAAGAGG TAAATGCTAC ACACGGAATG AGATACGATG GTAGCACAGA 4440
CTGCAAATTA ATAGCAAAGG TGGTGAAAAT GGCTGGATTT GGATTATTAT TTGAAGATAG 4500
AGCCAGTAAG ACTCGCTTGG TGGACAGAAT GTGGGATTTG AAAGTAGAGA GAAATTAAGA 4560
GTGACTCTGG ATCTGCTACC TAAGCACTAG GTACAAAGTG AGGAAGGAGG AACAGGTTGG 4620
GAAGGGCCCA CAGAATGAGG CCTCTATGTT AAATATGAGA CACCTATGGA ACATTCAAAC 4680
GGAGACATGA AGAGGCCGTC TAATATGCAA GTTTGACTGA GATGAGAAAG CAAGAGATGA 4740
GCATGCAGAG GCATTTAAAG CCTAAGCCTG GATGAGAGCA GCTAGGGCCA GCTAGAGACA 4800
GGAAAGAATG CTGAGGACTG TGTCCTAAGC TAACCAAGCA ACCTCCAGAG GTCCCACGGA 4860
GGACAAGGAT TCAGCAGAGA AGCCTGAGAA AGAGCCACCA AAAAAAGGAA GAAGTCCAGA 4920
AGAGTGCGGG ACACCAGGAA CCAAGCAAAG AAAGCGTGTG AGGGAGGAAG ATGCAAAAGT 4980
GTACAATCAG ATTTGGCAAG ATGGAGGCTG CTGACTGCCT TGACCAGCAC TGAGTCATGG 5040
GAATAAGGGC CTGGCTGGAA CAGGCTAGAG AACCTGAGGG AAGGAAGCAG AGGCACAGTA 5100
CAGACAACTA GTTCTTCCAG TGTGTTCTGC CCTAACCCAA GGCAGAGCAA ATGGAGCCAT 5160
CTAGGGAAGG GAGACACAGG GTAAAAGGAG TGTTTTGTTT TTATCTCAAG GTGAGAGTTT 5220
TTACAGACCA TTTTAATTGA TGGGAATGAC CTAGTTGAGA GGGAAAATGG TGTTGACAGG 5280
AAACTAACTA TAGATATAAG TATATCCTCA AGTTATAAAG GTTATTTTTT TCCAATATGT 5340
ATCAATTCCC TTTTCCTTCC TTTACTTGGA AGAGGAAAAA AAAAATAAGA AAAATAATCA 5400
AAAGAGAGGC TGGTTTCACT AACCTATCAT GTTAACATGA GAAAATGCAG GCAGGCACAC 5460
ATGTTCTTTT TATTGCTACC ATCCTTTTAT CTTTGTTTTA CAAATTTACT GTATTACAAA 5520
AAGAATTATT CAAAAAGTAA TTGAATTTTC TGTCTAATAA AAAAATGAAT TCACTTCTGT 5580
TTCATTTTGG TGAAGCAGTT TTTATCAGCA TGTTGAAAAT TTTACTTAGA AAAGAAATTT 5640
TAGGCTACTC TATCAACTAA GTCCTTCAGA AAACAATTCT GGCCTAGAAT CCACCATTTT 5700
TAAAGATAAA AAATAAAACT GTTAAATCTA AGAAGTTTCC TGCATCTGAT ACCAAAATAT 5760
TTTTGAAGGC AATGAATAAA AAATGAAACA TTTTTATTAA AAATATTTCA GTTACACATG 5820
TTTTGTTATA AAACAGTGCT CACTGTATCC TATTATGCAT ACACATCTAC AGGCACAGAA 5880
AAAAGCCTGA AACTATATTC ACCAAATTAA CAGTAGTTAT GCCCTGGTGG TGGGATGACT 5940
AAGTGAATTT TTAGGAACTT ATCTACGTTT AAATTTTCTA GAATGTACCA CGTGCACAAT 6000
AAAATTGATT TTTTAAGCAA TCAATGATGA AAATAACCAC ATACCATTCT TATTCATATA 6060
CATTGTGCCT TCCCTGGATC CTTACCGTGA GATATGGAAG ACAAATATCT GTTGAGACTG 6120
TTTTTCTTGG GTCACTATCT TGCCTCAAAT TTAGTCAGGA ATGATTAAAA ACAAGCAATT 6180
AAGAAGCACA TCTTAAAAGT CCACTATATT AGAATGGAAT ATTATTCAGC CATCAAAAGG 6240
AATGAGGTAC TGATACACGC TACCGCACAG ATAAACCTTG AAAATATTAC GCTAAGTGAT 6300
AGAAGCCAGA CATGAAAGAC CACATAGCAT ATAATTCCAT TTATATGAAA TGTCTAGAAT 6360
ATGCAAATGC ATACAGACAA AAAGTTGATA ACTGCCAAGA ACTGAGGAAG GGGGAATAGG 6420
GAGTGACTGA TAAAGGTATG GGGTTTCTTT CTCGGGTGAT GAAAATGTTC TGTAATTAGT 6480
GGTGATAGCA GCACAACCTT GTGAATATAC TAAAAACCAC TGAATTGTAC ATTTTATATG 6540
GGTGAATTTT ATGGTATGTG AATATATCAC TTTAAAAAAA AAAGAGCCCA CCGTATGCTT 6600
AGTATGTGAG AGATACAAAA ATCTCAGGCC GGGCATGGTG GCTCACACCT ATAATCCCAG 6660
CACTTTGGCA GGCAGAGGCA GGGGAATCAC TTGAGCCCAG GAATTTGAGA GCAGACCATC 6720
CGGGGCAACA TGGCAAAACC CTGTCTCTAC AAAAAAACAC AAAAAATTAG CCAAGCATGG 6780
TAGCGTATAC CTATAGTCCA AGCTACCCAG GAAGCTGAGG TGGGAGGGTC ACCTGAGTCC 6840
AGGAGATCAC TGCATGCTAG TCTGGGTATC AGAGTGAGAC CCTGTCTCAA AAGCTATATA 6900
TATATTTTTA TATGTTTAGT ACTCTATTAC ATGAATGAGA ATGTGGGTAA AATGGAAATT 6960
CAGAAATGAA AAAGATGATT ATGAACTGAG GTAGACGAGG TTTCAACAAA CAGGCACAAA 7020
TTAATAGTAA GCATAAGGAA ATAATGTTTT TAAATTATCT GTCATAACTT TACTTCCAAA 7080
ATGCCTTCTC CTGACACTAT ATGTTCTTTA AATACCATAT TCTCAAGAAT GTAAGATGAC 7140
TTCATTAGCT CCTTTCCCAT AAGGAACCAA GCAAAATGGG GTTCCCTAGA GTTAAAGCCT 7200
CTGGGAAGCT GTTGTGAGAA ATCCTACTAT TCTCATTGAA TCAAATTATA AATGTGTTCC 7260
TGCCAACTTT TGAGGTAAAT TGTTTTCATC ATAAAGAGTG CAGCAATAAT CAGGTCAAAA 7320
AAAAAAAAAA ACAGCTGTTA CAGATTTACC CATACTACAA GGACAGCAAA TTGCTGGGAC 7380
ATCTGAAAAG GCTCGTGACA TCTTGCTTAC TTGGTAACAG AGTACAGTTT TTCTTCCCCA 7440
GGTAGAAAAA GTGCATATTA GATCAGCCCT TCTTGGTGAC CACATACACA TTAAAATGTT 7500
AACTTCCTTT GAACTTAGAA ATCAGGAACA TCATTTTTTA TAGCAGGAAC ACAAAGAGAA 7560
GACATTCATC AATAAACAAT AAACTCTAAA GCATACTTAA GAGCAGAAGA TATAAATGAC 7620
AGATCCCACA AGACAATACA AATATGAAGA CATGCAGGGA AATAAATATT AATTAAAACA 7680
ATGAGGTACC ACTTAACAGC TACAGGTTGA GTATCCCCTA TCTGAAACGC TTGGGACCAG 7740
AAGTGTCTCG TATTTCAGAA TTTTTTCGGA TTTTAGAATA TATGGATAAG CAGTTGAGCA 7800
CCCCAATCCA AATATCCAAA ATCCAAAATG CACCAATGTG CATTTCCTTT GAGCATCATG 7860
TAGGCACTCA GAAAGTTTTC AATTCTGGAG CATTTCAGAT TTCAGATTTT TGGATTAAGG 7920
ATGCTCAACC TGTAGTAAAT TGTCTTCAAT TAAAAGACAA GATCCAACAT AGATGAGGTT 7980
GTACAAAAGT TATTTACTCA AAGATACGAT GGTAGTACTA TAAATTATTA AAAATCCTAC 8040
TTAGAAAGTA AAATAAATCA TGTATCAAAA GCCACAGAAT TATGTATATC TCATGACCTT 8100
ACTCCTGGGA ATTTATCCTA AAAAAAAAAA AACTGAAATG AAGAAAAACT CTAAATGCCT 8160
GAAGATTTTC ACTATAGTGT GAGGTCTATA TATAGTAAGA TGGAAAACTA AATATACAAA 8220
AACATGGAAA AGTCTTTAAA CAGGGAAAAA GTTAAGTAAA TTAAAATCAT TTGCCAGAAG 8280
GACTATGTCC AGCCACCAAC TCCTGTAAGT ATAAATAGAG TGTTAGGAAA ATGTTAAGAA 8340
AAAGTTATAA AACAGAACAA TACTAAGTGT TTTTAACTTT AAAAATATAT GTACCATCGG 8400
CCGGGCACAG TGGCTCACGC CTGTAATCCC AGAACTTTGG GAGGCCGAGG CAGGAGGATC 8460
ACGAGGTCAG GAGATCAAGA CCATCTTGGC TAACACGGTG AAACCCGTCT CTACTAAAAA 8520
TACAAAAAAA TTAGCCGGGC ATGGTGGCGG GCGCCTGTAG TCCCAGCTAC TCAGGAGGCT 8580
GGGGCAGGAG AATGGCATGA ACCTGGGAGG CGGAGCTTGC AGTGAGCCGA GATCGCGCCA 8640
CTGCACTCCA GCCTGGGAGA GAGAGTGAGA CTCTTTCTCA AAAAGCAGGC AGGGTGGCTC 8700
CTGCCTGTAA TCTCAGTATT TTGGGAGGCT GAGGCGGGAG GATCACTTCA GGCCAGGAGC 8760
TAGAGGCCAG CCTGGGCAAC ACAGTAAGAC CCCATTTCCC CATTTATATT AAAAAAAAAA 8820
AAAAAAATAG CTCGGTGTGG TAGCATGTAC CTGTAGTCCG TCCTAGCTAC TGAAGAGGCC 8880
GAGGTGGGAG GATCACTTGA CCCCAGGAAT TCAAGGTTAT AGTGAGCTAT GATCATGCCA 8940
CTACACTCCA GCTTGGGCGA CAGAGCAAGA CGCTGTCTCC CAAAAAAAAA AAAAAAAGTA 9000
AAAATATGTG TGTCTGTGTG TACACATGCA CACACATATG TACCATCTAA AAAAAAAAAA 9060
AAATATATAT ATATATATAT ATATATATAT ATATATATAC TGACCTGTAT GAAATACACA 9120
GAAAATCAGC GACACCAGAG GCAAGTATAG CTATCACTTT TAAATTTTTA AAATCTCAAC 9180
AGTAAAATAT TTTTATAATA ATGTATAATT TAAAAGTATA GTTAATACAA ACTGGGATAA 9240
AAGAACATGA AAATATTTCA TTAAAAATGG TAAATGTGAT TACAACTTGT TTCTACCTCC 9300
TATAGTCATC TATCTCAAGA GAAGGAAAGT CGAAGGAAAG ATAAAAAAAA AAAAAAAACA 9360
CTGTGTTAAG TTGTGCCAGG CCACCTACAG GCACACTGCA TAGTAATTCA TGTCAGTCAT 9420
ATCTAGATGA AGATGTGCCC TTCCAAAAAT TCAAAGTCAC AGATAATTTT CATTTAAAAA 9480
CAATGGGTCA TAGATTTATT TTAAGAGTCC TGTGTTTATA GAGCATGTAT GTACTGTAAC 9540
TATGATGTTA TGCTATCAAC ATAAGAATGA CTCATTTTAA AGAGGAATTA TTTCAGATCA 9600
AAATCTGAAA GACTTTTCTA AGAGGAAATA CAAAAAAAAA ACTGATTAGG GCATTTACAA 9660
GATGAGTCAG AGGCTAACAT TTATTCATTT GATTCAGAAA ATCATGTGAA GTTCTACAGA 9720
AAGAAGAAAG GAACCAAGAG TATAAGATGT TCCCTGTCAC CAAAGGGAAA TTACGCTCTA 9780
CAACAGCACC TTCAGAGTTT TCATTTACAA AAACTCAAAT CCTTCAAGTT TACCTAAGAG 9840
GAAGAAACAG AAAATTATGA AATGAACAAT CTATAAAAAG AGTGACACAA ATCCTCCCCA 9900
AATTTTGCAA CTCACAAGAA ATACCACAGG AATAGCCAGG CGATTATGCT TGTAGAGAGA 9960
TTAGGGGAAA ATCTGAATGG TTTCTGTGTT TCACAATTCC TCTGCAGAAA GATAAATGTA 10020
AAACTATTAC TTCAGTTTCT ATATTTTGTT GTACCCCTTA TGGAGGCAGG CCCGAAAATA 10080
TTTCTTGTAA GAGGAGAATG CCACTAGGCT TCCTATAACC CAGTCAAGCA AAAACACCTC 10140
TCCCAACACT GTGATACAGA GTGGGGATTA AATTAAGATA TAACCAAAGT TTCTTTCAAA 10200
CTCATACACA GCCATTTAGC CCAACTATGA CTTCTAACAC TGGGCGGGGT TTAGGAAGGA 10260
GATGCCGACC CTTCCAGTCC TCAAGAGTAC TCTGCCTGTC TCTGCACAGA CCTGGAGCTC 10320
TGCTCCAATG CTCACTCTGC CAGCTGAGTC TGCACACCAA GGGCACTCAT GAGCTTGGCT 10380
CCCTAATTCA GACATGCTGC ACCCTAGCTG TGAGCTAGGC TGCCAGTCTT CTGCAAGAAG 10440
TGTGCTGCTC CACTACCCCA GCTTGAGCTT GAGCTGTCCT TCCTCGTCTC CCCAATATCT 10500
GAGTAGGCAA CCCACAGGGG TCTCTGTGGA ACCTTCCTCA GGAGCCACAG GGACACTACA 10560
TATTTGAGTC CTTTCCCTCA AAGAGACACT CTCTACCTCC CTGACGATGG GTCCCAACCT 10620
TATTAAAGTT ATCAGAGAAT CACTGCTTAC AAAGGCCTAT CATGATTTCT TAGCTGTTTC 10680
TCTAGAGTTT ACTCTTGGAG CCATTAAACT GCTTTTAAAA ATATTCACCA ATTACCATAA 10740
GTTATGTATA CCGATGTTCT ATTAAGGCTC AATGATATTA AACCTACTTC TACACTAAGT 10800
GTACCACTTT ATATGATGGC ATATTTTTAA CATTAACCCA TCAGTTCCTA TCAGTTACAT 10860
CTGAGTTTAT TTAAAGCAAA ATCATAAAGT CATATTCAAA GGATTTTTTT TACTTCATAA 10920
ACTATTCCTT TGCTCACTTA CAGCAAGTTA GTAGAATTCA GAAATCAATA ACGTGAAGTC 10980
TCAATATCAA TTTGAACAAT ATTCTGTTAA AAATGTTAAT CAGGCATGGA CTATCCTGAC 11040
CATCCATTCA ATATCATCTG GAGCACACAA TCATATTCTG AAATAGTCAA CATTCTGGAA 11100
AAAAATGATA GAGCAAATAT GAAGTAGTTA CTTTAATTAA GGAAAAAATC ATAAAGTAGC 11160
CTGCTGGTCA TAGATGTCTG GTAAAAGAAC CACTTCATAT ACATGAATAG GTAACAGGGA 11220
CCTCTACATA GAAACCTATA GGAGTCATAT CCTATCAAAG CCAGCCATGC CAAAGAAGCT 11280
CCTGGTTCTA TGCCTTCCCC TCAATCCTAA CTTCTTGCTG ACTTCAACAA GAAGTTTCGT 11340
TCATTCACCC GTTAGTACTT ACTAAATACC TATTAAGAAA GGACAGTTAA AGCAAAAGGA 11400
ACACAGTGAT GAAAAAGCTT GCCTTCTTTA GGGCAGAGAA GAGAGGCTGG TAGCACACAA 11460
ATGAGCATGG TATATAAAGC GATATGATAA AGAATTATGG AAGTGATGAG GGGAGGATGG 11520
CTGATCATGA TTAGGAAAGA CACCTCAGGG TGAAGGGGAC TTTTGAGCTG AGACTGAAGA 11580
AGCCACAGCC ACTTGAAACA TCTGAAGGAA GACATTTCAT CAAAGGCCCA GAGGTGGTAA 11640
TGAACTTGGA CTATTCCATG ACCAGAAAAA AACGCCACAT CAGGAATACA GACTTATGCC 11700
AATGAGGGCA GGGAGAACAG GGGGTAGCTC AGGCAGGGCC TTGTAGGTCA AGAATAAGGA 11760
GTACGGACTT TATTGCAAGG GAAAAGTCAC TAGAGTAGTG ATTTACAACA TGCAATTCTC 11820
AGACAAACAG CATAAGCATC ACCTGGGAAC TTGTCAGAAA TATAAAGTTC CAGGCCCTGC 11880
TCCACATCTC CTGATTCAGA AACCCCAGAG GAGAGGCCCA GTACTCACAC TTAAGTTTAA 11940
GAACCACTGC ATTAGAGGGT TTTGAGCAGG GAAGTAACAT GAAACTAGGT TTCTGAGTAA 12000
TTTGCTGCAA ATAATGTAGA GTATTAATTT CACTAGCAGA TAACAACAGT GTGTATTAAT 12060
CTATGTAGTA TATATTAATT ATAATACCAG TAGTTAACCC AACAACAATA GCAATACATT 12120
ATGACACATA TACACTGGTA TTTATATTTG CATATTTTGA ATTTCAGGGA ATTCCATTTC 12180
AATTACAAGA AATATTAAGA CCTAAAATTT ATTTTAAATT ATCTACTCCA CAGTTATAGC 12240
CTCGAGTCAC CAAATGAGGA ATCTAAAATA GCCACTTTTC CTCACTTCTC TCCCCAGAGT 12300
AGCTCACCTG ATTCCTACTC TGTCCTGTAG TGTCAATTCA TCCCCATCCT TCCAGAATAA 12360
CTCAAAGACC ATAAAACTTC CTCCAATCCA TCCATCCCTA CCCACACACT CACCTCCAGC 12420
CAGAAGTAAA TGTTCTCTTT GCTTCTCTGA CAACCATTCA CACTGTAGTT GTCTGTATCC 12480
CTGTCTTATC TGTCCTACTG GTCTATACAT TCTTTAGTAC ACATGTTTTG GTTCTTAAAT 12540
GCCTCCTCCC TGGTTTTCCT CCTCCTACAT TATAACTCAC TCCCCAAAAA ACTCTGTCAG 12600
ATCTCACACA AAGCAAATAT GCAATACATG TTTGTTGGAC TGAACTGAAA CTGTGACGCA 12660
GGGATTCAAA GTTCCACGAA GAGGAGAAAG TTAACAGGCA ACAAGAACAT GACAAAGAGG 12720
ATGTTCACAT CCTGAAGCAT CAAGAAATGT TTATCTATAA ATGGTATTAC TTCACAGTGA 12780
ATGTTTTCAA AGCCAGACAA TGTCTCAAAG AATTCTGCTT TAAGTAAAAT TAAGAAACCT 12840
TTTCTCTTCT TTCAACTATG CCTGAAGCTG AATTTAGATA AGTTTCAAAT TCTGAACGTA 12900
TCCTCTAAAG CAACTCATCT TAGGTTACTC TGCTTCAATA TCTGTCATAA ACAATCAATG 12960
TATAAAGCAA AAGAACAAAT ACATTTAGTT AATTCCTCCC CGGCTCCAAC TATTGATAAG 13020
TTTAGTGTTG GTGTGCTTCC TTCTAAACTG AGTCTTGTTT GCCAGGCATT CGTCTTATTT 13080
TATGTAAAGG TACTGTTACA GATTTCATTC TGTTTTTTAC TTTTACTCAC TAAGCACTAC 13140
ATTTTTAAGA TCTATCCGTG ATGATCTAAC TACAACCGAT CCATTGCTTC TAGTTATTTC 13200
CTTCCTACCT CCCACTTTGC TATGGAAGTA GAGGCAAGAA CTACACTCAC CAAAGAAAAT 13260
CCAAAATAAG AATATTCATT CATCCATTAA CTCAAACAAT ATTTATTAAA TCCCTACAGT 13320
GTGCCAAACA CTGTGCTAAG TGCTAGAAAC ACAAAGATGA AAAGGCATGC TCCATGTCCT 13380
CACAGAGCTT ATGGAACAAT GAAGAAGCAC TGCAAACCAC GAAAAGGGTG CAATGTTGAG 13440
AAATGAGAAC TTCCTGGTGA AAGTACATTT AAAGCATTTG AAGTCCAGTG AGAACAGAAA 13500
AAAAAATCCC CTCCAAGCAG TGGAAGAAGG CTTAACATAA AAGAAGTACT ATTAAGCTAA 13560
AACTGTAGGA TGAATAAGAC AAGCAGGAAG AGGACCATCT AGGGAGAGAA ACACTGTGTA 13620
TAAAGACACA GGAAACTGTG GCATGCCCTC ACAACTATAG TCCTGGAACT GTTGAAGCAC 13680
AGAGGTGGGA CGCAAGGCAG GACAAAGAAG AGATGGGTCA ATTCCCAACC CACAAGCCAC 13740
GAATGTGCTG CAAAAACTTT CAATGCACAA AATTTGTTTT ATACACATGC TGTTATGGCA 13800
AAGTCCGATG GAGCGGAGCA CGTCATGGAG GGCAATATGC AAGAGTGGAG AGCAATATGC 13860
AACAGAGTAC AACTTGCTGT GAGCAAGAGG AAACACAATT CCGAAGGAAG GCCGAATGAA 13920
CCACGAGGTG ACCGGATGCT CTTCTGCACA GCACAAGGCA TTCCCACTAC TGTGCCATAG 13980
CTGGTGCTAT GTTTTAATAA CTGACTTGGT GTTTTGAGTT TTTCAATCAT TTCCATTATG 14040
CAGCTAAAAA TTCTGAAATG GAAATGTATC AATGACACAA AAAGGCTGAA ATCCACTGGG 14100
CTACACAATA AAGAAACTTT CTATCTCACT AAAGAGTTTA TATATTTTAT GCTGTAAGGA 14160
ACAGAGGTCA GACTTGAAGA ATTCTGGAGA GGGAAGAGAC ACATTGCTGT TTCAGAAAGA 14220
CCACCAGGGA AGCAGTGTGT TAAATGGCCT GATGGGGCAG AGAACAGAAA AGGTAAGAAA 14280
ATAGATAAGG AGAGCATTAC AACAGTCCAG GCAGGAGAGG GGTGAGGCCA AACAGGTGCC 14340
CCAGGAAATG GAGAAGAGGG ATCTGTGTGC CCTGGTGACT CAACAGCTCC AGGAGAAGAC 14400
AGAAGAGAGG AAAAGCAGCA GGATGAAAGC CCAGGTCCGT GGCTACTAAA AGCAACAAGC 14460
AAAACCTACC AGAGAAAGAT CCTATCTACC TTTAAAATAA ATGCATTATC CAAAATAGAT 14520
ACCCCCCAAA CTTTTCAGGA AATTAACAAA ATTTTTGAAA ATTACCTACA TATCACAAAC 14580
TAAGCAGTTA TTATCTAGAT TTTGTTGTGA TGCAGAAAAC ACTGCCACAA AGAGACCGTT 14640
CTAGAATTAA AGTTAACTCA GACTTGATTT TCCTAGGTCA CTCGCTACTT TGTGTCAGGA 14700
AAATGAAGAT ACTATTGTTT TAAAATTAAA AAAAAAAGGG GGGGGGCGGG GGGTCAAGGA 14760
ACTTTTAGGT TGAAGCATCA GAAGCTTCCA GAGCACTCTG GTCATGTGGT CAAAAGTAAA 14820
GCTGTCCTAA AGCATTTTAA GACAGACTAT GGCTTCCTTG AGAAACCTGA TACACCCTAC 14880
TCAGTTGAAA AGAAACATGG TGACAGAAGG CTTTTTCTCA AGCCTAAATT TAAACTGCTC 14940
TGTGTAGCTG TCAGAGCTCT GTGGTGATAT AAAAAGTATG GTTTCTCTTT AGCCCCATAG 15000
GAAGGAGCTT GTGGATACAG GAGTGATCTT CCACCATTCC TGTCTGGTCT TACTTCCAAC 15060
CCCGGGTAAG TGCTACTGTT TCTCCTCTCA CCCCTGGGGC TTCTGAGGGT CACTAAAACA 15120
ATTTATTAGA GCAAGTGACA AACTCTTGAG TGCCTTCACA ACCAATTCTG TCAGCTGGGC 15180
CTTAGGTGTG GTAAAAAATA AAAAATAAAT AAAATTAAAA CCCTTTAATT TATTTTTGGC 15240
AGCTTTCTGT AGACTTTCCT ACTCTTCCCA CCTTGCCCAA GTCTTACACT CTGGCACCTC 15300
TAAGGTCCAC TGTCCACACA GCAACAGAGT GAGCTTTCCT AATCAATCAG GTTGTCACTT 15360
TTGCTAACTA AACCTCTTCT GTGGCTCCCA CGTCCCTTCC CATGCCACCT CCACCCTTCC 15420
CTCTGGCCCG CGAAAACCTA TATGCTGACA GGTCTTTTGC TTCGGCTCTT GTCACTCTGC 15480
CCTCTGCCCA CGAAGCCCTG CCCCGCCCCC GCCGCCCCTC TCCCCTTGCC CCAGCCTCCA 15540
GTGCTTCCTC CCGGCCTCTG CACCAGTCCC TAGGAATCGT GCCCACTTGA AATGCTCCAC 15600
CTGCAAATCT TCACAGGACC AGCTCCTTCT TGTCATTCAG GTCTCAGCTG AAATGTCACT 15660
TCCTGACCAT CCAATCTAAA GTAGCCATCG CAGTCACATT ACCCTTCTTA AATCCCATTT 15720
AACTCTCATG TTTTTCTTTT TTGTTTATTT TCTCTCTCTC CCACCCAAAT CTCCCATTAA 15780
GCACTATGAA AGAAAGCTAA GCTCCCTGAA AACTTCCTTT CCTGTCTCCA TGGCATTTAC 15840
AACAGTGCCT GGAATACAGA AGATGTTAAC TAAATATTTG TTGAGCAGAT GTTATCCCCA 15900
AAAGGCCATC CAAAAACAAT TAAATGGTTA ATGAGGGAGA ATGAAAAGCA ATGATTTAAT 15960
GTGATTTCAT TCAAAATCAG CCCCTAATCT ATTTCCAACA AAGGTATCTG ACTACATTGA 16020
ATTACTGCTC CCTACTACAC GGGCAGCCCT GAAGCTGCAA GTGGAGACAC TCACTCCACT 16080
CCCATCTGGA CACTTCAAAG TCACTGCTGC ACCATTCGAG CAACTGGAAA TGGCTGAATG 16140
TCACTGGTCA TCTCACAGCA GACATTCTAT GCGTCCCTGT CCTCCACTTC TCCCAACATG 16200
CCTATCCTAC TCTGCTCCTT TCCTATTAGG GTGATCCAAA AGTAATTGTG GTTTTGCCAT 16260
CAAAGGTGAT GGTAAGAACC GCAATTACTT TTGCACCAAC CTAATACATC ATCAACTTCA 16320
AGCCGTATTT ACAGATATCA TCTCAGGAAA GACTACTCAA CACCCCTCAT ACAAAAGCTA 16380
ATTATCACAC CCCTTCTCTT TCCCTGCAGA TGTGGAAGAT CTGAGATCTC TATGGTAATA 16440
TTAGATAGAG GTGGGAAGAA ATAGCTATTG AGATGTTTCC TTTGCCCAGG GGGAGGTAAC 16500
CACCTCCACA TCATTTGAAA GTTGATAAGA GAACTATCTG CCAATCTTCT CATCAGTATG 16560
GATTTAAATA AGGGACGATG TCTCCATTTT TTTCTTTTTT TTTTTTTTCC ATTTTTCCTT 16620
TTCTACTTTA AAACTACAGT AAGGTTATGC TTTGAAAAGC AATTTTTGAA GTTACCATTA 16680
GCCAAAAGAA CATCATTACC ATTGTTTGTC CTGTCAAACA TATAAAAATA TTCTAACCCA 16740
AGCATTTGCC ATCTTGAACA GAGTATGTGT TTGCAGGCAG ACAGTTCGAA TCTCATTTCT 16800
ACTAGTGACC AGAAACAAAT TACTTAAGCC CTTTGAGCTT CAAATTCCTT ATCTGTTGAA 16860
TGAGAGTGGG AAGATCAACT TCAGAGTGTA ATAAGGGGAT TAGACGGGAT GACCAACCTA 16920
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