EnhancerAtlas 2.0: an updated resource with typical enhancer annotation in 600 tissue/cell types across nine species

EnhancerAtlas 2.0

Tag

Content

EnhancerAtlas ID

HS105-47055

Organism

Homo sapiens

Tissue/cell

IMR90

Coordinate

chr2:201999220-201999710

Target genes

Number: 20
Name	Ensembl ID

BZW1	ENSG00000082153
RP11	ENSG00000260006
CLK1	ENSG00000013441
PPIL3	ENSG00000240344
NIF3L1	ENSG00000196290
U6	ENSG00000252916
AC005037.3	ENSG00000183308
ORC2	ENSG00000115942
AC007272.2	ENSG00000225695
NDUFB3	ENSG00000119013
FAM126B	ENSG00000155744
CFLAR	ENSG00000003402
IMPDH1P10	ENSG00000232133
AC007283.5	ENSG00000234431
CASP10	ENSG00000003400
CASP8	ENSG00000064012
STRADB	ENSG00000082146
AC007256.5	ENSG00000213090
TRAK2	ENSG00000115993
TMEM237	ENSG00000155755

TF binding sites/motifs

Number: 2

JASPAR ID

Coordinate

Motif Sequence

Strand

-Log10(p-value)

IRF1	MA0050.2	chr2:201999635-201999656	GGAAGGAAAATGAAACTAGAA	-	6.92
IRF2	MA0051.1	chr2:201999639-201999657	GGAAAATGAAACTAGAAC	+	6.97

dbSUPER

Number of super-enhancer constituents: 14
ID	Coordinate	Tissue/cell

SE_00060	chr2:201979028-202002115	Adipose_Nuclei
SE_11080	chr2:201999350-202000978	CD20
SE_17962	chr2:201999324-202001753	CD4p_CD25-_CD45ROp_Memory
SE_18402	chr2:201999408-202001986	CD4p_CD25-_Il17-_PMAstim_Th
SE_22486	chr2:201999393-202000688	CD8_primiary
SE_30085	chr2:201999603-202000508	Fetal_Muscle
SE_35842	chr2:201999318-202001349	HMEC
SE_38014	chr2:201989179-202001533	HUVEC
SE_40675	chr2:201995226-201999368	Left_Ventricle
SE_45746	chr2:201999384-202001801	Osteoblasts
SE_51286	chr2:201999547-202001003	Skeletal_Muscle
SE_58856	chr2:201980298-202001868	Ly3
SE_61030	chr2:201980009-202025097	HBL1
SE_62239	chr2:201978946-202023992	Tonsil

HEDD

Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder
Number of disease enhancers: 1
Chromosome	Start	End

chr2

201999446

201999699

GeneHancer

Number: 1
ID	Chromosome	Start	End

GH02I201134

chr2

201999030

202002242

Enhancer Sequence

AGTGGTGGGC GCCTGTAATC CCAGCTACTT GGGAGGCTGA GGCAGGAGAA TTGCTAGAAC 60
CCAGGAGGCA GAGGTTGCAG TAAGCCAAGA TTGTGCTATT GCACTCCAGC CTGGGCTATA 120
GAGCCAGACT CCATCTCAAA AATTAAAATA AAATAAAATA AAATAAAATA AAATAAAATA 180
AAATAAAAAA ATATAAAATA AAATAACATT CTAGTTGGCC CTACATGGTA CTGTTGACCT 240
AAGGATAGGC CAGGAAATGT TTGAGAACCT ATTGTTTCTA AAATATGACA ATAGGTCCTC 300
AAAATAGGCA GGCCAGTGCC TGCCTGTAAC GATTCAGATA AGTCATTGCT TGAGAATTTC 360
CTCATGTTCC TAATGATTAT AGTTTTGTTT CTTAAGTCCC ATCAAATGCA AAATGGGAAG 420
GAAAATGAAA CTAGAACTCC CTTTTTGGTT TCTCCTAGTA ATTGTCTCTC CCAGCCATTT 480
ATATATATCT 490