EnhancerAtlas 2.0: an updated resource with typical enhancer annotation in 600 tissue/cell types across nine species

EnhancerAtlas 2.0

Tag

Content

EnhancerAtlas ID

HS105-38856

Organism

Homo sapiens

Tissue/cell

IMR90

Coordinate

chr19:10283850-10284540

Target genes

Number: 32
Name	Ensembl ID

CTD	ENSG00000239830
ZNF846	ENSG00000196605
FBXL12	ENSG00000127452
PIN1	ENSG00000127445
OLFM2	ENSG00000105088
COL5A3	ENSG00000080573
C19orf66	ENSG00000130813
ANGPTL6	ENSG00000130812
PPAN	ENSG00000243207
P2RY11	ENSG00000244165
EIF3G	ENSG00000130811
DNMT1	ENSG00000130816
S1PR2	ENSG00000175898
MRPL4	ENSG00000105364
ICAM1	ENSG00000090339
ICAM4	ENSG00000105371
ICAM5	ENSG00000105376
ZGLP1	ENSG00000220201
FDX1L	ENSG00000167807
RAVER1	ENSG00000161847
ICAM3	ENSG00000076662
TYK2	ENSG00000105397
CDC37	ENSG00000105401
PDE4A	ENSG00000065989
KEAP1	ENSG00000079999
S1PR5	ENSG00000180739
ATG4D	ENSG00000130734
KRI1	ENSG00000129347
CDKN2D	ENSG00000129355
SLC44A2	ENSG00000129353
ILF3	ENSG00000129351
QTRT1	ENSG00000213339

TF binding sites/motifs

Number: 9

JASPAR ID

Coordinate

Motif Sequence

Strand

-Log10(p-value)

FOSL1	MA0477.1	chr19:10284446-10284457	CATGAGTCACC	-	6.62
JUND	MA0491.1	chr19:10284446-10284457	CATGAGTCACC	-	6.02
Nr2f6(var.2)	MA0728.1	chr19:10284386-10284401	TGAACTCCTGACCTC	-	6.22
RFX1	MA0509.2	chr19:10284128-10284144	GGTTGCCATGGAAACA	+	6.99
RFX1	MA0509.2	chr19:10284128-10284144	GGTTGCCATGGAAACA	-	7
RFX2	MA0600.2	chr19:10284128-10284144	GGTTGCCATGGAAACA	-	7.31
RFX2	MA0600.2	chr19:10284128-10284144	GGTTGCCATGGAAACA	+	7.42
RFX5	MA0510.2	chr19:10284128-10284144	GGTTGCCATGGAAACA	+	7.26
RFX5	MA0510.2	chr19:10284128-10284144	GGTTGCCATGGAAACA	-	7.31

HEDD

Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder
Number of disease enhancers: 1
Chromosome	Start	End

chr19

10284213

10284535

GeneHancer

Number: 1
ID	Chromosome	Start	End

GH19I010173

chr19

10284241

10284510

Enhancer Sequence

CTGTCAAGCA AAATAACACA GACCCCAAGT GTGAGTGCCA GGAGCTTCCC CAAAGAAGCA 60
GTTTTCATAA AGCTCCTCTT TCCCCCAAAA GCAATCTTCA TTATCTCAGG AGCCCTGACA 120
GACACATACT CATTTAACAT TTAGTATTTG ATATGACTTT TACACCTGGT TCGAATGCCA 180
GCTGCCCTCG ATTCATTCCT TCCAAGAAAA CAGGAGAATT CTACTTGAAT CTAAACGCTA 240
ATGATCTGAC CCCAAATTCA GATACTTCAT AACGATATGG TTGCCATGGA AACACACGAT 300
AAAGTTCTTC TTTTTAAACT TTTTTTTTTT TTTTTGAGAT GGAGTCTTGC TCTGTCACTC 360
AGGCTGGAGT GCAGTGGAAT GATCTCAGAT CACTGCAGCC TCTACCTCCT GGGTTCAAGC 420
AATCCTTCTG ACTCAGCCTC CTGAGTAGCT GGGATTAAAG GCACATTCCA CCACGCCCAG 480
CTAAGTTTTG AATTTTTAGT AGAGACGGGG TTTCGCCATG TTGGTCAGGC TGGTCTTGAA 540
CTCCTGACCT CAAGTGATTC GCCCATCTTG GCCTCCCAAA GTGCTGAGAT TACAGGCATG 600
AGTCACCGTG CCCGGCCTTA AACTTTCTGA AAAAGTTTTG TGATCAAGAT TACACAACTC 660
GTAGAACAAA AAGAAAGGTA TAGTAACTAT 690