EnhancerAtlas 2.0: an updated resource with typical enhancer annotation in 600 tissue/cell types across nine species

EnhancerAtlas 2.0

Tag

Content

EnhancerAtlas ID

HS091-28594

Organism

Homo sapiens

Tissue/cell

HepG2

Coordinate

chr2:201962400-201963850

Target genes

Number: 26
Name	Ensembl ID

BZW1	ENSG00000082153
CLK1	ENSG00000013441
U6	ENSG00000201499
PPIL3	ENSG00000240344
NIF3L1	ENSG00000196290
ORC2	ENSG00000115942
AC007272.2	ENSG00000225695
AC005037.4	ENSG00000226658
NDUFB3	ENSG00000119013
FAM126B	ENSG00000155744
RP11	ENSG00000232719
AC007272.3	ENSG00000224672
AC007272.1	ENSG00000237078
CFLAR	ENSG00000003402
IMPDH1P10	ENSG00000232133
AC007283.4	ENSG00000235579
AC007283.5	ENSG00000234431
CASP10	ENSG00000003400
MTND5P25	ENSG00000227348
MTND4P23	ENSG00000225796
AC005037.6	ENSG00000235318
CASP8	ENSG00000064012
ALS2CR12	ENSG00000155749
STRADB	ENSG00000082146
AC007256.5	ENSG00000213090
TRAK2	ENSG00000115993

TF binding sites/motifs

Number: 11

JASPAR ID

Coordinate

Motif Sequence

Strand

-Log10(p-value)

EWSR1-FLI1	MA0149.1	chr2:201963174-201963192	GGAAGGAAGGAAGGAAAG	+	10.53
EWSR1-FLI1	MA0149.1	chr2:201963192-201963210	GGAGGGAGGGAGGGAGGG	+	6.03
EWSR1-FLI1	MA0149.1	chr2:201963178-201963196	GGAAGGAAGGAAAGGGAG	+	6.07
EWSR1-FLI1	MA0149.1	chr2:201963187-201963205	GAAAGGGAGGGAGGGAGG	+	6.13
EWSR1-FLI1	MA0149.1	chr2:201963170-201963188	AGAAGGAAGGAAGGAAGG	+	9.09
Foxd3	MA0041.1	chr2:201962611-201962623	AAACAAACAAAC	-	6.32
ZNF263	MA0528.1	chr2:201963175-201963196	GAAGGAAGGAAGGAAAGGGAG	+	6.12
ZNF263	MA0528.1	chr2:201963179-201963200	GAAGGAAGGAAAGGGAGGGAG	+	6.25
ZNF263	MA0528.1	chr2:201963193-201963214	GAGGGAGGGAGGGAGGGAGCG	+	6.44
ZNF263	MA0528.1	chr2:201963171-201963192	GAAGGAAGGAAGGAAGGAAAG	+	6.48
ZNF263	MA0528.1	chr2:201963189-201963210	AAGGGAGGGAGGGAGGGAGGG	+	7.05

HEDD

Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder
Number of disease enhancers: 1
Chromosome	Start	End

chr2

201963000

201963271

Enhancer Sequence

CCCGGCCAAA TCAACTTTTA TGGAGCAATA AATTCCCCTT TTAGTTGACC ATCTAAGGTC 60
GATCTTGCTG GGTATGGTAG CACATGACTG TAATCCCAGT TACTTGGGAG CCTGAGACAG 120
GAGAATCACT TGAACCCAAG AGGCAGAGGT TGCGGGAGCC AAGATCACAC CACTGCGCTC 180
CAGCCTGGGT GACAGAGCGA GACTCCATTT CAAACAAACA AACCAAAAAA AAACATTGGT 240
GACCTCCGGG GAGCGGGGAC CACCAGGTTG ACCAAGGAGG GATGAACCTG GGAGGTGAAC 300
TGGCCCAGAT CAGAAATAGA GCAGGTCAAA AACTCCTGTG CTGATCAGTA GTGGGATCTG 360
CTTGTGATTA GCCACTGCAC TGTAGCCTGG GCAACATAGT GAGACCTTGT CTATTAAAAA 420
AAAATAAAAA TAAAAAAAAT AAAAAAAATA AAAAAAAAAA TAAAGTCAAT CATTTAAAAA 480
AGAAAGAAAC ACAGTTGGGT GCGGTGGCTC ACACCTGTAA TCCCAGCACT TTAGGAGGCC 540
GAGGCAGGCA GATCACGAGG TCAGAAGATT GAGACCATCC TGGCTAACAC AGTGAAACCC 600
TGTCTCTACT AAAAATACAA ATATTAGCCG GGCATGGTGG CAGGCGCCTG TAATCCCAAC 660
TATTCTGGAA GCTGAGACAG GAGAATTGCT TGAACCTGGG AGGCAGAGGT TACAGTGAGC 720
CGAGATTGTG CCACTGCACT CCAGCCTGGG TGACAGAGAG AGATTCCATC AGAAGGAAGG 780
AAGGAAGGAA AGGGAGGGAG GGAGGGAGGG AGCGAGGGAG CCCAGGCACA GACAGTGGTT 840
CATGCCTGTA ATCCCAGCAC TTTGGGAGGC CGGGGTGAGG TGAGAGGAGC ACTTGAGCCC 900
AGGAGTTCAA GGTTTCAAGG TTATAGCATG CCAACACTGC ACTCCAGCCT GGGTGACAGA 960
ATAGGACTCT ATCTCTTAAA AAAAAAAAAA AAAGAAAAAG AAAAGTCAGA TAAAGAGTAA 1020
CTGAGAAAAT AAACACACAA CAGGTTTTGA AGGAGTTTTA TAATATGTAA CTTTTCCATC 1080
AATGCACACC ACCATTTTTT TTTTTTTTTT TTTTGAGATG GAATCTCACT CTGTCACCCA 1140
GGCTGGAATG CAGTGGCACG ATCTTGGCTC ACTGCGAACT CCGCCTCCCG AGTTCATGCC 1200
ATTCTACTGC CTCAGCCTCC CGAGTAGCTG GGACTACAGG CACCCGCCAC CACGCCCAGC 1260
TAATTTTTTG TACGAGGTTT CACCTTGTTA GCCAGGATAG TCTCAATCTC CTGACCTCGT 1320
GATCTGCCCG CCTCAGCCTC CCAAAGTGCT GGGATTACAG GCATGAGCCC CTGCACCCAG 1380
CCCCTCCCCC ACTTTTTTTT TGAGACGGAG TCTTGCTCTG TCGCTCAGGC TGGAGTGCAG 1440
TGGCATGATC 1450