EnhancerAtlas 2.0: an updated resource with typical enhancer annotation in 600 tissue/cell types across nine species

EnhancerAtlas 2.0

Tag

Content

EnhancerAtlas ID

HS091-23062

Organism

Homo sapiens

Tissue/cell

HepG2

Coordinate

chr19:6730400-6730990

Target genes

Number: 17
Name	Ensembl ID

MLLT1	ENSG00000130382
CLPP	ENSG00000125656
ALKBH7	ENSG00000125652
PSPN	ENSG00000125650
GTF2F1	ENSG00000125651
KHSRP	ENSG00000088247
SLC25A41	ENSG00000181240
SLC25A23	ENSG00000125648
CRB3	ENSG00000130545
DENND1C	ENSG00000205744
TUBB4A	ENSG00000104833
TNFSF9	ENSG00000125657
CD70	ENSG00000125726
TNFSF14	ENSG00000125735
GPR108	ENSG00000125734
TRIP10	ENSG00000125733
SH2D3A	ENSG00000125731

TF binding sites/motifs

Number: 14

JASPAR ID

Coordinate

Motif Sequence

Strand

-Log10(p-value)

KLF16	MA0741.1	chr19:6730596-6730607	GCCCCGCCCCC	+	6.02
KLF5	MA0599.1	chr19:6730470-6730480	GCCCCGCCCC	+	6.02
KLF5	MA0599.1	chr19:6730596-6730606	GCCCCGCCCC	+	6.02
SP1	MA0079.4	chr19:6730644-6730659	CAGGCCCCGCCCACC	+	6.67
SP1	MA0079.4	chr19:6730593-6730608	TAGGCCCCGCCCCCA	+	6.73
SP1	MA0079.4	chr19:6730705-6730720	TAGGCCCCGCCCACC	+	6.85
SP2	MA0516.2	chr19:6730643-6730660	TCAGGCCCCGCCCACCT	+	6.06
SP2	MA0516.2	chr19:6730592-6730609	CTAGGCCCCGCCCCCAG	+	6.16
SP2	MA0516.2	chr19:6730704-6730721	CTAGGCCCCGCCCACCC	+	6.85
SP3	MA0746.2	chr19:6730646-6730659	GGCCCCGCCCACC	+	6.14
SP3	MA0746.2	chr19:6730707-6730720	GGCCCCGCCCACC	+	6.14
SP4	MA0685.1	chr19:6730593-6730610	TAGGCCCCGCCCCCAGC	+	6.45
SP4	MA0685.1	chr19:6730705-6730722	TAGGCCCCGCCCACCCC	+	6.7
SP4	MA0685.1	chr19:6730644-6730661	CAGGCCCCGCCCACCTT	+	6.99

dbSUPER

Number of super-enhancer constituents: 3
ID	Coordinate	Tissue/cell

SE_23570	chr19:6729529-6731564	Colon_Crypt_1
SE_24935	chr19:6729520-6731579	Colon_Crypt_3
SE_65665	chr19:6729469-6730943	Pancreatic_islets

HEDD

Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder
Number of disease enhancers: 1
Chromosome	Start	End

chr19

6730400

6730551

GeneHancer

Number: 1
ID	Chromosome	Start	End

GH19I006728

chr19

6728132

6731335

Enhancer Sequence

GGCAGACAGC GAGGAGGCGT CTAGCGTTGC AGGGCAGCAG GCCCCACCCA CTCTACCCGG 60
AACCACTCAG GCCCCGCCCC ACTCCCCCCA ACCACAGCAG CCCTGGCCTT GCCCACTCTA 120
CCCCAGACTC ACCCAGGCTG CACCCACCTC GCTCCCACAG CAGCGCAGGC CCTACCCTTC 180
TACTCCAACC ACCTAGGCCC CGCCCCCAGC AGCCCTGGCC CCACCCACTC TACCCGTAAC 240
CACTCAGGCC CCGCCCACCT TACTGCCATA GCAGCCCAGG CCCCACCCGT TCTACCCGAA 300
CTACCTAGGC CCCGCCCACC CCCGCCCCCA GAGCGGCCCT GGGTGTCTCC CTAGCGGCCC 360
TAACCCCACC CCTAGCTCAG CCTGGCCTTA GGTACTCCAC AGCTGTCCGG TCCCCACCTG 420
CACAGCTGCC CTGGCTGCCC CCCATCTCCC CTCCATCCCT TCTCAACAGC AGGCTCTGCC 480
CTAACACTGC CCCCAGGGCT GCTACAGTCC CTCCCCCCTG CCCACCCTGC CCGTAGAGCT 540
GCCCACCCCC TACTCCACCC CCAGAGCCGC CGGCCCTGCC CATGGTGCCC 590