EnhancerAtlas 2.0: an updated resource with typical enhancer annotation in 600 tissue/cell types across nine species

EnhancerAtlas 2.0

Tag

Content

EnhancerAtlas ID

HS091-23048

Organism

Homo sapiens

Tissue/cell

HepG2

Coordinate

chr19:6693500-6694440

Target genes

Number: 17
Name	Ensembl ID

MLLT1	ENSG00000130382
CLPP	ENSG00000125656
ALKBH7	ENSG00000125652
GTF2F1	ENSG00000125651
KHSRP	ENSG00000088247
SLC25A23	ENSG00000125648
CRB3	ENSG00000130545
DENND1C	ENSG00000205744
TUBB4A	ENSG00000104833
TNFSF9	ENSG00000125657
CD70	ENSG00000125726
TNFSF14	ENSG00000125735
C3	ENSG00000125730
GPR108	ENSG00000125734
TRIP10	ENSG00000125733
SH2D3A	ENSG00000125731
EMR1	ENSG00000174837

TF binding sites/motifs

Number: 15

JASPAR ID

Coordinate

Motif Sequence

Strand

-Log10(p-value)

KLF14	MA0740.1	chr19:6693889-6693903	GGATGGGCGTGGCC	-	6.08
Klf12	MA0742.1	chr19:6693952-6693967	TCAGAGGGCGTGGCC	-	6.23
Klf12	MA0742.1	chr19:6694059-6694074	TCAGAGGGCGTGGCC	-	6.23
Klf12	MA0742.1	chr19:6694166-6694181	TCAGAGGGCGTGGCC	-	6.23
Klf12	MA0742.1	chr19:6694346-6694361	GGGGAGGGCGTGGTC	-	6.26
Klf12	MA0742.1	chr19:6693888-6693903	GGGATGGGCGTGGCC	-	6.46
Klf1	MA0493.1	chr19:6693855-6693866	AGGGTGTGGCC	-	6.32
PLAG1	MA0163.1	chr19:6694088-6694102	GGGGCCCTCAGGGG	+	6.37
PLAG1	MA0163.1	chr19:6694195-6694209	GGGGCCCTCAGGGG	+	6.37
SP1	MA0079.4	chr19:6693890-6693905	GATGGGCGTGGCCTT	-	6.43
SP1	MA0079.4	chr19:6693954-6693969	AGAGGGCGTGGCCTT	-	6
SP1	MA0079.4	chr19:6694061-6694076	AGAGGGCGTGGCCTT	-	6
SP1	MA0079.4	chr19:6694168-6694183	AGAGGGCGTGGCCTT	-	6
SP3	MA0746.2	chr19:6693890-6693903	GATGGGCGTGGCC	-	6.23
SP4	MA0685.1	chr19:6693888-6693905	GGGATGGGCGTGGCCTT	-	6.25

HEDD

Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder
Number of disease enhancers: 1
Chromosome	Start	End

chr19

6693802

6693995

Enhancer Sequence

GCAGAGAAGA GAGAGGAACC CCCAAAAGAG CCGGGGCTGA GCAGAGGGGG CACGCCAGAA 60
AGGGCAGGGG CGGGGTGCAG AGAGGGGACA GGGGCTCAGG GTGGCGGAGG GGTTCTGGGA 120
GGAGGGGACC TTAAAAAGGG AAGGACTCAA AGAGGGTGGG GGATCAGAAC GAGGAGGTGG 180
AAAAGTTCTC AAGAGGACAA GGGATTCAGA GAGGAGAAGG ATATTGAGGG TGGGGGGCTT 240
TCAGGGAGGG GAGGGCTCTC AGAGAGGGGG TGGAGTCTCA GGGAAGAGGC ATGGCCTGGA 300
GAGGACGTGG GGCCTCAGAT GAGAGTGGCT GGGACAGGAG GTGGCGCCTC ACAGAAGGGT 360
GTGGCCTTGA GAAGATGTGG GGACCCAGGG GATGGGCGTG GCCTTGAAAA GAGGCAGGGT 420
CTCGAGATTC TGGCCTGGGA GGAGTCAGGG CCTCAGAGGG CGTGGCCTTG AGAAGAGGTG 480
GGAGGCCCTC AGGGGATGGG CATGGCCTTG AGGAGAGGCG GGGTCTCATG AAGAGCCTGG 540
CCTGGGAGGA GTCAGGGCCT CAGAGGGCGT GGCCTTGAGA AGAGGTGGGG GGCCCTCAGG 600
GGATGGGCAT GGCCTTGAGG AGAGGCGGGG TCTCATGAAG AGCCTGGCCT GGGAGGAGTC 660
AGGGCCTCAG AGGGCGTGGC CTTGAGAAGA GGTGGGGGGC CCTCAGGGGA TGGGCATGGC 720
CTTGAGGAGA GGCGGGGTCT CATGAAAAGC CTGGCCTGGG AGGAGTCAGG GCCTCAGAGG 780
GCGTAGCCTT GAGAAGAGGT GGGGCCTCAA ATGAGGGGAG TGGCTAGGAG AGAAGGTGGA 840
GCCTCAGGGG AGGGCGTGGT CTTGAGATGA GGTGGGATCT TAGGGGAGGG ATGCGCTCGG 900
AAAGGGGTCC CTGGGGTCTC CAAGAGGGGC AGGGAGCCCA 940