EnhancerAtlas 2.0: an updated resource with typical enhancer annotation in 600 tissue/cell types across nine species

EnhancerAtlas 2.0

Tag

Content

EnhancerAtlas ID

HS076-27696

Organism

Homo sapiens

Tissue/cell

Coordinate

chr19:4325980-4326930

Target genes

Number: 32
Name	Ensembl ID

HMG20B	ENSG00000064961
PIP5K1C	ENSG00000186111
MRPL54	ENSG00000183617
ATCAY	ENSG00000167654
ITGB1BP3	ENSG00000077009
MIR637	ENSG00000207733
DAPK3	ENSG00000167657
EEF2	ENSG00000167658
PIAS4	ENSG00000105229
AC016586.1	ENSG00000205147
ZBTB7A	ENSG00000178951
MAP2K2	ENSG00000126934
CREB3L3	ENSG00000060566
SIRT6	ENSG00000077463
ANKRD24	ENSG00000089847
EBI3	ENSG00000105246
CCDC94	ENSG00000105248
SHD	ENSG00000105251
TMIGD2	ENSG00000167664
FSD1	ENSG00000105255
SH3GL1	ENSG00000141985
CHAF1A	ENSG00000167670
UBXN6	ENSG00000167671
AC011498.1	ENSG00000167674
AC011498.2	ENSG00000220693
PLIN4	ENSG00000167676
PLIN5	ENSG00000214456
LRG1	ENSG00000171236
SEMA6B	ENSG00000167680
TNFAIP8L1	ENSG00000185361
C19orf10	ENSG00000074842
PLIN3	ENSG00000105355

TF binding sites/motifs

Number: 9

JASPAR ID

Coordinate

Motif Sequence

Strand

-Log10(p-value)

KLF14	MA0740.1	chr19:4326871-4326885	GAGGGGGCGTGGCT	-	6.73
KLF16	MA0741.1	chr19:4326873-4326884	GGGGGCGTGGC	-	6.62
NR2C2	MA0504.1	chr19:4326555-4326570	TACCCTCTGACCCCT	-	6.24
RREB1	MA0073.1	chr19:4326775-4326795	CCCCCACACACACACCCTGA	+	6.02
SP1	MA0079.4	chr19:4326872-4326887	AGGGGGCGTGGCTGA	-	6.42
SP3	MA0746.2	chr19:4326872-4326885	AGGGGGCGTGGCT	-	6.46
SP4	MA0685.1	chr19:4326870-4326887	TGAGGGGGCGTGGCTGA	-	6.83
SP8	MA0747.1	chr19:4326872-4326884	AGGGGGCGTGGC	-	6.92
STAT3	MA0144.2	chr19:4326624-4326635	CTTCTGGGAAG	+	6.14

HEDD

Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder
Number of disease enhancers: 1
Chromosome	Start	End

chr19

4326007

4326453

Enhancer Sequence

TCTTTGTGTG GCATACACGT GTACACTAAT TGAATCTAGA TAAGTTAAAG TGCAACGTTT 60
GTACACACAC ACCTGTGGTG TGTATACGTG TGTGACTGCA CGCCTGCTGA GGTGGCTGCT 120
TTAGTCCTTG TCTACATGAG TGCGTTTTGC CCGTGTATCT ACACGTGTCC GAGTTTGTGC 180
CGGTGCACGG ACGTATCTGC ATTTATGTGT ACACATGTGA TTGTGGCATG ACACAGGTGT 240
ATCTGTGCTA CATAGCATTT GTATGTGACT GGAATTGGGG CACACGTGTA TTTATGCATG 300
TGTGATCTGT TGTGCCCGCA CAAGTGTGTG TCACCTTCTG GCTAGGCAGG TGGCCACAGT 360
TGCATGGATC ATGCATGTGT AATGTGTGTG TGGATGTGGC ACTTGGGGGT CCTTGCATAC 420
GCCCAGACCA GGGAAGACCA GACAACCCAC GCTACATTCC TTTCTAGTGT GTTCTCTGCC 480
TCCTCTTCCC ACTCCATAAA CAGGACCGAT TTCCACCTCT TTCCCAACAC CCACCCGGAT 540
TCTCGGTCCC TGTGGGGCTA CTGCTTGTCC GGGTGTACCC TCTGACCCCT CAATGCCCAT 600
TTCTACCTAA GGAGATCCTT TGGGACCATC TGCAAAGACC CACTCTTCTG GGAAGCTTTC 660
CCTGCTCTGC CCCCATCTTC TCCCGAACTC TAGGCGCCTC CCCCGAGCCC AGGTTTTTCC 720
TCCACCCCAA ATTCAACCCT ACAGGATGAG AGTGTCTGTG TTTAGCTCTG TCCCAAGCTG 780
GGACCCCCGC CCCCTCCCCC ACACACACAC CCTGACGGCA GGGTCTGAGT CATTTCTGTC 840
CCTGCAACTT TGGGAACATC AGATGCAGGA GGTGCAGCCA CCAAACTGAC TGAGGGGGCG 900
TGGCTGAATG CGGGGTCCTC GATCCCTCCC ACCTCGGCCC GCGGGAAGGG 950