| Tag | Content |
|---|
EnhancerAtlas ID | HS073-09492 |
Organism | Homo sapiens |
Tissue/cell | GM19238 |
Coordinate | chr21:35304150-35304950 |
Target genes | |
TF binding sites/motifs | | TF | JASPAR ID | Coordinate | Motif Sequence | Strand | -Log10(p-value) |
| IRF1 | MA0050.2 | chr21:35304328-35304349 | AAAGTGAAAGTAAAAGTTGGG | - | 6.91 | | IRF1 | MA0050.2 | chr21:35304322-35304343 | GGAGCAAAAGTGAAAGTAAAA | - | 7.8 | | IRF2 | MA0051.1 | chr21:35304326-35304344 | CAAAAGTGAAAGTAAAAG | + | 6.37 |
|
| | Number of super-enhancer constituents: 19 | ID | Coordinate | Tissue/cell |
| SE_11967 | chr21:35303740-35306253 | CD3 | | SE_14467 | chr21:35303679-35307483 | CD4_Memory_Primary_7pool | | SE_15465 | chr21:35303660-35306531 | CD4_Memory_Primary_8pool | | SE_15922 | chr21:35303675-35305316 | CD4_Naive_Primary_7pool | | SE_16316 | chr21:35303644-35312136 | CD4_Naive_Primary_8pool | | SE_17056 | chr21:35303750-35306263 | CD4p_CD225int_CD127p_Tmem | | SE_17721 | chr21:35303712-35312370 | CD4p_CD25-_CD45RAp_Naive | | SE_18012 | chr21:35303591-35312416 | CD4p_CD25-_CD45ROp_Memory | | SE_18597 | chr21:35303660-35313783 | CD4p_CD25-_Il17-_PMAstim_Th | | SE_19434 | chr21:35303740-35307592 | CD4p_CD25-_Il17p_PMAstim_Th17 | | SE_20266 | chr21:35303773-35306316 | CD56 | | SE_20793 | chr21:35303657-35307510 | CD8_Memory_7pool | | SE_21525 | chr21:35303686-35306285 | CD8_Naive_7pool | | SE_22015 | chr21:35303660-35307599 | CD8_Naive_8pool | | SE_22550 | chr21:35303727-35312418 | CD8_primiary | | SE_25585 | chr21:35303739-35306240 | DND41 | | SE_55454 | chr21:35303827-35304258 | Thymus | | SE_55454 | chr21:35304302-35305017 | Thymus | | SE_63012 | chr21:35296130-35324786 | Tonsil |
|
| | Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder | | Number of disease enhancers: 1 | Chromosome | Start | End |
|
Enhancer Sequence | CAAGATTTAT TTTATAAAAA AGAGCGTTTA TGTTTGGTTC AAACAAAAAT GTGAGAACGG 60
CCGAGGCTTT GTAGGAGTTC ACCACGAAAA AGGAAATTAC ATGGTAAAAA AAAAAAAAAG 120
AAAAAAAAGA AAGATAAATT CTACATTTTT TTCTTTATAT AATTATTTAG CTGGAGCAAA 180
AGTGAAAGTA AAAGTTGGGG CAAGGAAACA CATTCAGATG TGGGGAAGTG CTCCCAGAAC 240
GTGGGACAGC GAGTGGCGGA GTCCGATTTT GAAATGCTCC AGAGAGAATA TGATCTTCCT 300
GGACCCCACA GTGGGATGCA CCACCCCAAA AACCATTGGC AAAGTTTGGT GACAGAGGAA 360
TCATTTTGTT TCTTTTTATG CATAAAGAAC ACACAGAAAG GAACACTTGC TTTGAGGATC 420
CTGGTAAATC AGGCTGGTGT TCTGTTGGGG CAGTGCAGTT TGGTACAAGG AAGTGGTCAC 480
TGCTGACCCC ACGGAGAGGC TGGGAAAAGC GTAGATGAGG TGACTGGAGA ATAAAGGAGG 540
CTTTTTCTAG CTCAAGGTTT AAAGGCAGCC ACAGTGTCTG TAGCAGATGA ATTAGTGTGA 600
CCTTGGAGAT GGCCCCTTGA CCCGAAAGTG GTAAAGAATG CCATACTTTT CATTTTGCAG 660
GACACCTCCT TGGGGGAGGC TGGGCTGGTA GCATATTTCT ACGGGCTTAT GGTTCTGTGG 720
ATAGAATTGT AGGGCTGGAT AAAAGCACTG GCTATTTTGA GTTTTTAAGC AATCAGGGGG 780
CTATTAGTGG GGTGGTCTTT 800
|
