| Tag | Content |
|---|
EnhancerAtlas ID | HS073-08500 |
Organism | Homo sapiens |
Tissue/cell | GM19238 |
Coordinate | chr2:106411670-106418130 |
Target genes | |
TF binding sites/motifs | | TF | JASPAR ID | Coordinate | Motif Sequence | Strand | -Log10(p-value) |
| CEBPA | MA0102.3 | chr2:106413854-106413865 | TATTGTGCAAT | - | 6.62 | | EWSR1-FLI1 | MA0149.1 | chr2:106412276-106412294 | CCTCCCTAACTTCCTTCC | - | 6.55 | | EWSR1-FLI1 | MA0149.1 | chr2:106412280-106412298 | CCTAACTTCCTTCCTTCG | - | 6.66 | | FOXC1 | MA0032.2 | chr2:106416135-106416146 | ATGTTTACATA | - | 6.32 | | FOXC1 | MA0032.2 | chr2:106412906-106412917 | TATGTAAATAT | + | 6.62 | | GATA2 | MA0036.3 | chr2:106417929-106417940 | ACAGATAAGAA | - | 6.14 | | Gata1 | MA0035.3 | chr2:106417929-106417940 | ACAGATAAGAA | - | 6.62 | | IRF1 | MA0050.2 | chr2:106415781-106415802 | CTATACTTTTACTTTTTCATT | + | 6.01 | | JUN(var.2) | MA0489.1 | chr2:106414813-106414827 | CTGAGTCATTTTTT | - | 6.45 | | KLF4 | MA0039.3 | chr2:106412125-106412136 | GCAGGGTGTGG | - | 6.62 | | MAX | MA0058.3 | chr2:106417846-106417856 | AGCACGTGGT | - | 6.02 | | Mecom | MA0029.1 | chr2:106412793-106412807 | GTTTATCTTATCTC | - | 6.67 | | NFE2L1 | MA0089.2 | chr2:106414809-106414824 | TTAGCTGAGTCATTT | - | 6.35 | | NR2C2 | MA0504.1 | chr2:106411812-106411827 | AGAGGTCAAAGGTGG | + | 6.16 | | Nkx3-2 | MA0122.3 | chr2:106414382-106414395 | TTTAAGTGTTTAA | - | 6.37 | | YY1 | MA0095.2 | chr2:106416277-106416289 | TCCGCCATCTTG | - | 6.27 |
|
| | Number of super-enhancer constituents: 28 | ID | Coordinate | Tissue/cell |
| SE_10292 | chr2:106411222-106421168 | CD19_Primary | | SE_10910 | chr2:106411012-106422732 | CD20 | | SE_11843 | chr2:106410974-106421804 | CD3 | | SE_13211 | chr2:106414449-106416414 | CD34_Primary_RO01480 | | SE_13211 | chr2:106416461-106417636 | CD34_Primary_RO01480 | | SE_14420 | chr2:106411367-106421747 | CD4_Memory_Primary_7pool | | SE_15409 | chr2:106411390-106418244 | CD4_Memory_Primary_8pool | | SE_16297 | chr2:106411616-106421189 | CD4_Naive_Primary_8pool | | SE_17245 | chr2:106411580-106416265 | CD4p_CD225int_CD127p_Tmem | | SE_17245 | chr2:106416758-106421242 | CD4p_CD225int_CD127p_Tmem | | SE_17337 | chr2:106410985-106421895 | CD4p_CD25-_CD45RAp_Naive | | SE_17777 | chr2:106411100-106422091 | CD4p_CD25-_CD45ROp_Memory | | SE_18243 | chr2:106389599-106421920 | CD4p_CD25-_Il17-_PMAstim_Th | | SE_19126 | chr2:106411161-106421690 | CD4p_CD25-_Il17p_PMAstim_Th17 | | SE_20619 | chr2:106411144-106421245 | CD56 | | SE_21274 | chr2:106411361-106417913 | CD8_Memory_7pool | | SE_21873 | chr2:106411466-106421035 | CD8_Naive_7pool | | SE_21946 | chr2:106411177-106421890 | CD8_Naive_8pool | | SE_22311 | chr2:106410918-106422177 | CD8_primiary | | SE_39779 | chr2:106411494-106415700 | Jurkat | | SE_39779 | chr2:106415888-106416856 | Jurkat | | SE_39779 | chr2:106417453-106418191 | Jurkat | | SE_44057 | chr2:106411021-106416312 | MM1S | | SE_53622 | chr2:106411722-106419614 | Spleen | | SE_62262 | chr2:106353762-106421483 | Tonsil | | SE_66643 | chr2:106411494-106415700 | Jurkat | | SE_66643 | chr2:106415888-106416856 | Jurkat | | SE_66643 | chr2:106417453-106418191 | Jurkat |
|
| | Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder | | Number of disease enhancers: 7 | Chromosome | Start | End |
| chr2 | 106415000 | 106418000 | | chr2 | 106414093 | 106414226 | | chr2 | 106415106 | 106415442 | | chr2 | 106416912 | 106417146 | | chr2 | 106417583 | 106417937 | | chr2 | 106411914 | 106413111 | | chr2 | 106413728 | 106414372 |
|
| | Number: 1 | ID | Chromosome | Start | End |
| GH02I105794 | chr2 | 106411262 | 106421477 |
|
Enhancer Sequence | CATTCCATGG GTTTGGACAA ATGTATAATA ATAATTATTG CTTTTTAATG TGAGCAAACA 60
CATATGTGTA TACAGTGATA TATTTTTAAT TTTTTTTTTC CTCAAATAAG CAATAGCATA 120
CTCTATACAC TTTTCCCAAG CAAGAGGTCA AAGGTGGTTT TCTAATTATA TGGTATATTG 180
TAACTTAATC ATGATATTGA GTTAAACTGA ATGGGCCTGT TTATTTAGTT ATTTTGAAAC 240
GGGTAATTAT AAAAACTGCT GCATAAATAT TTGAGTCATA TTCCAAAAGA GTTAGAAAAT 300
ACATGGATAT TCCTGTCTTA TTTTTGCTTT AACAAACTTG GTCTATTTAG TTTACATGTA 360
TGCTCCGTCA GTGGTTCTCA GCCAGGGTGA TTTCATTCCC CAAGGGATAT TCAGCAGGCA 420
GTGTCTGCAG GCGTTGTTGA TTGTCACCAA TTTAGGCAGG GTGTGGATTG TTGTTAAACA 480
TCCTACAACG CAGGGGACAG CTCCACGACA AAGAATTACC GAAACGTCTG TATGCCCCTG 540
GTGAGAAACA CTGCTCATGT TCAACCAGGT ATTTGAGTCA TTATTCCTCC CTCTAGACCT 600
CTCCCTCCTC CCTAACTTCC TTCCTTCGCC GCTTCCTCTC ATCTTCCACG CACCCTCCCC 660
CCAGTCTTTT TCAGTAAAAC TAGGTATTTA CATCTAGGAC TTTAGGAAAA CATGAATCAT 720
TTAAAATGAA ACACATCAAC GATATATTCT TTATTACCAG TCTTGTAAAA AGAGCAAAAC 780
AGTTTAGCAT TTGAAAGCTC TATTGTAGTT TGCTCTGGTA TAAATCATAT GTGCAGTCAA 840
ACTTTTTTTG GAAAGCTAAT TCTGCTTTAT GATACAGGTC CCAAGAAGAC AGAATTTTAT 900
TAGGTGCATG CACATGGAAT ACCAACTTCA GGGTTGAAAG TGACTGAGGT TGATAGTCTC 960
TGTATTGGCC GCCCTCTGGG CACTGTGGCT TCAGGGTTGA AAGACAATCA TTTGCAGGCG 1020
TGTGTAAGTA TATATGGCTG GTGGGCAGAG TGGTGGCTTT GCTGCTCTTG CAAGGCTGTT 1080
TTGTCATTGA TGGCACACAG GAGAGTGCTG GAGGTTAGTG TCAGTTTATC TTATCTCTGT 1140
ACTTCCTGTT GCCTCACTTT AGGATCTTAA GAAATATTCA ATTTCCACTA AAAAGAGGAG 1200
TGAACAATTC AATGTTTTGC TGTTTTAAGG GTCATGTATG TAAATATGGA TGAATGGGGG 1260
CATTGGAGCA GGGAGCACAT GGGGTATTAT TGGCACCGGT TGCAGAGAGG GCCTGGGGAC 1320
ATGAGTGTGT GGCACAGAAC GCAGGTGTTC AGATCGGCAG CGTCTGGACT GAGCCTGGGA 1380
GCTGGAAGGC TGGAGATGGT GCTTTTCTTC CTTTTGCATT TGGCAAGGAA GAGTATCCCG 1440
TAGTTTAGTG TTATTCCAGA AGCTCTCGGC ATCATGTTTA TTCCCTTTCT TTTTTTTCCC 1500
TTGTACTTTC TCATACCTCT ATCAGATAAA TTAAATGAAT TGGAAAAATA ACTAAGCATT 1560
TCTCTTTGAC GCAGGTAAAT GCAGTATACA TTTGATTCCA TGGAAAGGAA ATATATATAA 1620
TTAGAACACT TATAGACATT AGTGGTGACA GTTCACAGGT TAGTCTGCCC TCTCAGGAGT 1680
TGTCTTGATA AAATAAATTT TATTAAGCAT GTTACTTGTA AGTGTCAGCA CTTATCTGTG 1740
GTTGGTTCAG TACCCCTAGC TGGGGTGAGT GTTTGCTGTG ATGATGGTTA CAAGCATAGT 1800
CTTGCAGAAA TGGATTTAGT CATCACAGTC CCTTTTTTAT TTTAACTTTA TGTCTCTAAG 1860
ACATAAAAAT TTATTATCCT TTTTAGGCCT TTGACTCACA GTTTGTACCA CCATCTTTTC 1920
TTTCAGCATC TCCCCCACCC ACAAGAAAAA AGTTGACATT GATTTCTAAT CCTTTCTGTC 1980
TGGCCAAATT CAGGATCTTA GAAAGGACAC CCCTATTTCA GCTCCTATAC TAGTGTTTTA 2040
AGGGGAACCT TTAAAATGGG ATTCTGAAGC CTTGGCTGAT TTTTCTTTTC TGCACAGGAA 2100
ATAACCAATT TGTGCTATTT CTGGGTGGTG TGTGTTGAAC TCACAGTTCT AGGACCGGAA 2160
GAGACTGCCA GCCATGCGGT TCCATATTGT GCAATGCAAG GGCAGAAATG GTATCCAGGT 2220
CTTTCTAAGG GGGAAAAAAC CAGTATGGCC AAGCAGCAGG CTGCCAGGCT GTGCGGGCTA 2280
GCAGAAGGGA GGTTCTTAAA TTCTCTGCAC CCATGTGAGG GAGGCTGCTC TCTTGACAGC 2340
GTCTTAGGGT CAGGATGGCT GGAATGGAGC GTGGAGCCTG GTCTGGTTGG AGTCCCTGTG 2400
TGGCCTTTTG GAGATGAGTA TGGTAACAGT GAGGCAGGAA GTGGCTGGAT TTGCAGCGAC 2460
TGTGTGGAGC CTCCCTGTTT AGGCTTAGTG AGCTGATGCA AAGTCTTTCG TAACCATGAT 2520
CAGTTAAAAC AAAACACCTG ATGTTGTGGC CTCCTGTCAG CTTTTGTCCT CCTGTAGAAA 2580
CAAGATGCTT CTAGAAAACC AGTTTGTAAA TTTGGCACAG AAAAAAAACC CTTTCAGCAA 2640
TTTGGTGTGG ACTCTGCTTG TTAATTTATG GCTTCGCAAC TTTTTTTAAG CTACCGGCAC 2700
TAACAGCAGA TCTTTAAGTG TTTAATCGTC CCAAGTCAGG TTTGACTGTG GGCTGACTAG 2760
CTATAGTGAT CTAATTTGGT TCATTTCCTA GGAGAAGAAA ATTATAACCA CATTTTTATT 2820
AATTTATGGT TTTGATCCAT CTATTTTAGA CTCAATATTA AATCATCCCC TACTTCCAGA 2880
AGATGTGTTT TTGAACATAA GTATCTTTAG GATTTAATAT TCTATGAAAG GAGTAGGAGC 2940
TAATGTTCGC TTGTTGTAAT GTTTGTTTTC TTCTGATATG ATGATTTTGT TGAAAAAATG 3000
TATTTGAAAG AGTAACGTGT AGGTAAGAAA TAAGTTAGCC AAAACCATAC TTCAAGGGAA 3060
GCCTCCCTCC TATCCTGGGA GCCCGGATAG CCTCACTGTG GCCTCTTGTT TGTACATCCA 3120
GAATATTCTT GAAACTGGGT TAGCTGAGTC ATTTTTTTTT CTTCTTTCAG TGTTCTCCTT 3180
TTTTCTTTTT ATAAAATGAA GAGATCTGTC CACAAGTCTA GCTTTTAACA ATGAGAAAAA 3240
GCACTGAATT GTACACTTTA AACAGTGAAC CAGTTTGGGG TCTGGTTTAG AGAGAAGAAA 3300
TAAGGGTTAA AATTGTTTTC ATCTTCCATA TCTGATTCAT ATAATCAGAT ATGAATAGTG 3360
AAGTTCCCCA AAGATACATG TAAGCTTGGA GTAAAGACAA AATGTATGCA TTACTTTGAT 3420
GGGGGAAGCC TGTGGTGAAC CCACTGAGGT TGCTGGTGAT TAAGTTTATG TGGACGGTGA 3480
ATCTCAACAG AATGAAAATA AACTGTGGGT GTCTATTTTG AAGCAGATGA ACCAGGCAGC 3540
AAAGCAGTAG CTGTGGTTCT TCATAGATAA ATACATTTAG GGAAATTAAT ACAAAATGTT 3600
CTTACCTTAT TTTTCTGAGT TGTTCACCGA GCTTCCTCAG ATGTTAACAT CTTAACCACA 3660
GCACAGTTTT GAAAATCAGG AAGTTATACC AGGTTGTTGT CATCACACTT TCTGATCTCC 3720
AGTGGTCTGA AAGGTGAGAG GTGATATCTT AGTATCATTT TAGTGAAGTT CAGATGTCCC 3780
TTTTCATCAG TTTGAAGGCC TTATATTTTC TTACCTGGTT TTCCTTGGCC CACGGTTTTC 3840
TTGGTGTGTT GGTCTTTTCT TGTGTCAAGT TTATTTAAGA AGCTCTCGCT GTGTCCTGTC 3900
TGTCCTTCGT GTCCTAAGTT GCAAATGTTT TCTCCTAGCT TTTTATTTGT CTTTGGAATC 3960
TATCTGTGGT ATATTTTATC ATGTAAGAAA ATTTTTTATG TTTATGTAGT TGAATTCATC 4020
CCTCTTTTAT GGTTTCTGGA ATTTGAGTCC TAGGTTTAAA AAAAAAAAGT TCTTCCTTCA 4080
GGGTTATAAA GGGTGTTTTC CATATGTCCT TCTATACTTT TACTTTTTCA TTGTAAATCT 4140
TGGATACCTT TGGAATTTAT CCTGTTGTGG GCGTGAGATG TGGCTCCAGC TTTCTTTCAG 4200
ATGGCCAACC AGAGTACCCC ATGGCCATTT ATTGAGAAGG CTGTCTCTTC CCTGGGGACT 4260
TGACTTGAGA TAGTGCCTTT ATCATACACT GAATTCCCAG AGGCCTCTGG GTCTGTTTCC 4320
CATGTTCCTG CTTCCTAGTG TTTCGTTAGT CTGTCTATCT GCCACACCAA ACACGAGCTG 4380
ATGAGTTATT TGAAAACTTC CTATTTTAAA GCAGAAAAAC AAAACGGAAT ACCACTATAT 4440
GAAAGCCTAT AAAAAGCTAA TTACCATGTT TACATAAATG GTACAATAGC AGCCCAGAGG 4500
TCACTGGGTT GTTTTGGCAT GGAGGGATGC TTCCCTCTAC CTCAAGCCTA AAAGTGGTTA 4560
AGATAGATCC ATTTCAAGAA GCCATTGGTC CTTACCTGGC CTTCCCCTCC GCCATCTTGC 4620
CACTATGTTC TTGGCTATGG AGACAGGATC AGGGAATTTG ATTGAAAATC ATTAATGACA 4680
TAACTTTTTT TTTTAACAGT GAGAGAAACA CTCAAACACT ACATTTTGCA AAGTTTGTAA 4740
GAATCCCTCC CAAGAGTTTC CTTTGGTCAG CGTAGCTTCT GGTAATAAGG AAATCTGTCA 4800
TTTGGAAACA CCATCTTTGT TCATGTGGTA TCATTAGATG TGTCTTTGCA CCAGCATTTG 4860
ACAGAGACCA TGACAGTTTT CCTCCTGAGC CCTTACTTTG TGAGAAGAGA GGGTCAGTGC 4920
AGCCATGTAG CCTGGCTGCA CCGTATAGTC TGGCTCTCCC TGGTCTCCGG CACGGGGGCC 4980
ACATGCCCAG GGTGAACACC AAGGAAGGGA TCCTGAGTCC CCAGGCTCCG GTTCCAACTG 5040
CACACCTTGT TCTCTGTCCT CCCTGTGCAC GCCACCTAAT TCTCTGCTGT GAACGGGGTA 5100
ATGAGGTGTT GTCTTGTTGT AAAGATTGAT TGAGATAGTG CATAAAGAGG GCCTAGTCTG 5160
GTCTGTGGTA CCCAGGATAG GGTTGGTAAA TGATTGCCAT TAGCATTCAT CTGTTTCCTT 5220
TCCTCTTTAG AGCATGAAAT TCTGAGGTGC ACAGTTCCTG AGCTTTAAAC TTGAGTGCTG 5280
GAGGCCAAGG AAAATAGAAT ACAATTCAGG ATTACGTAAG AGTGGCATAT GTGTGTGTGA 5340
TTAGCCCATA GAAGGCGGAA ACCCAGCTGA CATGGGGTTA GTCTCAAAGT TCTACTAAGG 5400
CCTAAGAACA AGAAACATTC ATCCTGTTTT TGGTCTGTTT GAGATAAATG GACCGAGAGA 5460
GTGGGTTTGG TGCTTGGTTT CTGATGGGAC CAGTTGCAGG AGCACAGTTG ATCAACTGTC 5520
ATGAACGTCT GTGTTTTGTT TTGTTTGTTA AAAAGAAGAA TCTTGAAAGT AGAGGCTTCA 5580
GAACAAATGT CGTGAAGAAG GAATTGAAGC TCAACATGGG AAAAAGTGAG TGGGAGAGCA 5640
CCTTGCTGCT TTTCAATCCA AGCTCGAGGT TCCATGGGAT TACATGCCTG TCCAGGTGGT 5700
TGGCAGAAGC CCCTTTAGTA TTCTTTGAGG GGTCTTGAAG GAGAGGAGAA GTGTCAGAAG 5760
ATTGGAGACA GGCAAATGTT CTAATTTTCT AAACGCAGAA AAAAGCAGAA GCAGGGAAGA 5820
GATACTTAAA CAGGTTACTG AATGGAGGTG AAAGCTGGGC GTGCTGAGCC CGTCAGCATT 5880
TGTTCTCTTT GATGCAGTGT GGCTTGATGT CTGCAGGGTG TCTGGTGAGG TTGGACCCTC 5940
TTAGGTGAGT GTCCCATAAA TCTGTGGTGT TAATATGCCT CCTTACCCTG GGACCTCCCC 6000
TCCAACCCTG CTCACTGGCT AGAGGCCTGC CGGGCTGTCA TCTCCTTGGG GACAGGACTG 6060
TGATCATTTG CCCCCTTGTT GGACGTCATT GTAGGGATCC CCCAGCCCCA GCCCTTACGT 6120
CTGTTGACCA GCTCACTCGG CTTGCCTCCC CCCTTCCCCA TGTCATCGTG TGCACCAGCA 6180
CGTGGTTGAG GGATGTGCTT TTTTCTTTTT TTTTTTTTCT CCTCACAGTC TATTTACACA 6240
AAACCAGTGC ACAACGTTAA CAGATAAGAA GAAAGACTGA GGGACAAAGC ATGACAGAGA 6300
CCTTTGTCAC GTGCTGGCTG TAGCAGTCGA GTGAGGAGAG GGGCCCATGG CACAAGGAAA 6360
GCTGGAGTTA GGGGGAGGGA TGGTCTGACC TGCATCCGCA TTGTCTTGCT GCCTCCTGCT 6420
TGGCTTCTTA CCTACCCTGT GAGAGCAGCC TCGGGATTGT 6460
|
