EnhancerAtlas 2.0: an updated resource with typical enhancer annotation in 600 tissue/cell types across nine species

EnhancerAtlas 2.0

Tag

Content

EnhancerAtlas ID

HS073-04909

Organism

Homo sapiens

Tissue/cell

GM19238

Coordinate

chr16:499850-500940

Target genes

Number: 28
Name	Ensembl ID

Z97634.5	ENSG00000236829
Z97634.3	ENSG00000241145
AL049542.1	ENSG00000256323
LA16c	ENSG00000261691
JMJD8	ENSG00000161999
FAM195A	ENSG00000172366
STUB1	ENSG00000103266
C16orf13	ENSG00000130731
RHBDL1	ENSG00000103269
RAB40C	ENSG00000197562
NHLRC4	ENSG00000257108
PIGQ	ENSG00000007541
FAM173A	ENSG00000103254
WDR90	ENSG00000161996
WDR24	ENSG00000127580
NME4	ENSG00000103202
TMEM8A	ENSG00000129925
MRPL28	ENSG00000086504
AXIN1	ENSG00000103126
RAB11FIP3	ENSG00000090565
DECR2	ENSG00000242612
AL022341.3	ENSG00000228201
SNRNP25	ENSG00000161981
POLR3K	ENSG00000161980
MPG	ENSG00000103152
NPRL3	ENSG00000103148
RHOT2	ENSG00000140983
SOLH	ENSG00000103326

TF binding sites/motifs

Number: 6

JASPAR ID

Coordinate

Motif Sequence

Strand

-Log10(p-value)

ESR2	MA0258.2	chr16:500696-500711	AGGGCATGCTGACCT	-	7.19
EWSR1-FLI1	MA0149.1	chr16:500508-500526	TCTTCCTCCTTTACTTCC	-	6.12
IRF1	MA0050.2	chr16:500494-500515	TTTTAGTTTCTTTTTCTTCCT	+	6.2
NR2C2	MA0504.1	chr16:500687-500702	GTAGGTCAGAGGGCA	+	6
Nr5a2	MA0505.1	chr16:500703-500718	GCTGACCTTGAAAGC	-	6
RREB1	MA0073.1	chr16:500840-500860	CCCCCACCCCACCCCACCCT	+	6.14

HEDD

Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder
Number of disease enhancers: 1
Chromosome	Start	End

chr16

499940

500813

GeneHancer

Number: 1
ID	Chromosome	Start	End

GH16I000449

chr16

499961

500736

Enhancer Sequence

TGAGGCAGGA GAATTGTTTG AACCCGGGAA GCAGAGGTTG CAGTGAGCCA AGGTCGTGCC 60
ACTGCACTCT AGCCTGGGCG ACAGAGTGAG GCTCCATCTC AAAAAAAAAT TTTGTTTTAA 120
AGATTAAGTT AACCTCGTCA CAGTGACTGT GCCACCACAT GCACAGGCCT TGCCCACACT 180
CAAGAGAGGG GGTCTTAGAA TTCTGCCTGC TACCATGGTC TAGTCTTGGC ACACCTTCCT 240
TGACAACATG GAAGCCAGGT CACTACCCAG GCCACCTACA AGGAAGTTCA CCATTTGACC 300
TGCCGAACGT GCACAACAAA CTTTTTTTCT CTTTCTTGAG ACAGGGTCTC ACTCTGTCGC 360
CCAGGCTGGA GTGCAGTGGA ACAATCTTGG TATACTGCAA CCTCTGCCTC CCGGGCTCAA 420
GCGATCCTTC TGTCTCACCC TCCCGAGTAG CTGGGACCAC AAGCATGCAC CACCATGCCC 480
AGCTCTGGCT AATTTTTTGT ATTTTTGGTA GATATTTTTG TATTTTTGTT TCACTGTGGT 540
GCCCAGGTCA GTTTCGAACT CCTGACCTCA AGTGATCCCC TGGCCTCCAA AAGTGCTGGG 600
ATGACAGATG TGACCCACCA CGCCCAACCA AGTATTGGAT AACTTTTTAG TTTCTTTTTC 660
TTCCTCCTTT ACTTCCGCTC AGGGGTCTAG GTCTGAGTCA GGGCTTGAGG GTGTCCCCAT 720
GGGGGCTGGT GTTACCCAGG ACACTGCAGC GGCTAGCAGG GCTTGGCTGG GCTGGCGAAT 780
GAGGGCCCCA CTTCTCTTTT TTGTACAGGG AAGGGACCGA GGATCTGAGT GACATCTGTA 840
GGTCAGAGGG CATGCTGACC TTGAAAGCAA GGTGGGAATG GAGTTCTATG AGCTGAGGAG 900
TCCCAGCTGG CTCGCATTCT AGAGAAGCGC CATAAAGGGA GTCTATTCAT TAGCCCCAGG 960
GAGAGAGCCT CCCGCTCCCT CCCTCCCCGC CCCCCACCCC ACCCCACCCT TAGGAGCTGC 1020
TCACCTTCCC CTCGCCTGGG GCACACACCT GCTTCTCCAG GGACCAGACC TGAAGTGCAG 1080
GAAGGAGCCC 1090