EnhancerAtlas 2.0: an updated resource with typical enhancer annotation in 600 tissue/cell types across nine species

EnhancerAtlas 2.0

Tag

Content

EnhancerAtlas ID

HS003-20135

Organism

Homo sapiens

Tissue/cell

A549

Coordinate

chr17:48601150-48602230

Target genes

Number: 27
Name	Ensembl ID

RP11	ENSG00000251179
XYLT2	ENSG00000015532
MRPL27	ENSG00000108826
EME1	ENSG00000154920
Y	ENSG00000206824
LRRC59	ENSG00000108829
ACSF2	ENSG00000167107
MRPS21P9	ENSG00000262759
CHAD	ENSG00000136457
RSAD1	ENSG00000136444
MYCBPAP	ENSG00000136449
EPN3	ENSG00000049283
SPATA20	ENSG00000006282
CACNA1G	ENSG00000006283
CTB	ENSG00000251239
ABCC3	ENSG00000108846
ANKRD40	ENSG00000154945
LUC7L3	ENSG00000108848
LINC00483	ENSG00000167117
WFIKKN2	ENSG00000173714
RPL5P33	ENSG00000243521
AC091062.2	ENSG00000229980
TOB1	ENSG00000141232
SPAG9	ENSG00000008294
NME1	ENSG00000239672
NME2	ENSG00000011052
UTP18	ENSG00000011260

TF binding sites/motifs

Number: 8

JASPAR ID

Coordinate

Motif Sequence

Strand

-Log10(p-value)

Lhx3	MA0135.1	chr17:48601529-48601542	TAATTAATTAATA	+	6.25
Lhx3	MA0135.1	chr17:48601526-48601539	GAATAATTAATTA	-	7.12
Myod1	MA0499.1	chr17:48601968-48601981	AGCAGCTGTCACT	+	6.64
Myog	MA0500.1	chr17:48601967-48601978	CAGCAGCTGTC	-	6.14
POU4F2	MA0683.1	chr17:48601524-48601540	GAGAATAATTAATTAA	+	6.29
POU6F1	MA0628.1	chr17:48601531-48601541	ATTAATTAAT	+	6.02
POU6F1	MA0628.1	chr17:48601531-48601541	ATTAATTAAT	-	6.02
Tcf12	MA0521.1	chr17:48601967-48601978	CAGCAGCTGTC	-	6.02

HEDD

Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder
Number of disease enhancers: 1
Chromosome	Start	End

chr17

48601348

48601409

Enhancer Sequence

GGACCCAGGA CCATGGCCCC TGTGGACATC AGGTAGGGTA TCCTGGTGTT CTTCCTGGCA 60
GTGACTGAAG GGATCATATT TCTCCCAGCC TAAGAGGAGA ATTGGATTTT TAGCAAACAG 120
GTAACTACTC TTGCTCCACA AACACTTCCC AGGGCTTGTG ATTTAAAAGA TGGGTGCGCT 180
GGCTAGGCAG GCATGGAGCA GCTTGCAGCA ATGCCATGCA TGGCCCCACT GAGTTAGAAA 240
GAAATTAGAC TGAGCCTTAA GAGGCAGACT GTAAAGTACA ATGTGTGGCC CTATGTACTG 300
GTCTGTGTTT TGTTCATCGC TGTCTGGTAC TACACAGTGG AGTTGCATTT AAGCGACAAG 360
ACTTCAAAAC CAGGGAGAAT AATTAATTAA TACATAGCAG CATGAGTCTG CCCACCGTCC 420
CACTCAATCA GCTGACAACT CGAGTGAGTG TGAGGTGGGA GCTTGGAATC TGTCGTCCGC 480
AGTCAGTTTC ACAGTGTGGC CATTTGAGCC GTGCATCCTG GGATTTGGTG GAAAGCTGTG 540
CTTTTTTATT CATTGTGGCC CCCAATCACA AGGCCGGCTC CTTCATGTGG GGCTCAGCCA 600
GTGGTGATCA AAGGTAATTT TGACAATGTC ATGCTTGCTT TACTCATTGA CTGTACAACC 660
CATGTCTCAC ACAAGGCGCC CCTCCCGTGT TTCTGTGACA CTCACTGAAG CCTGATGAAG 720
GTTCACCACC ATCCTCAGAA GCACCCCCAC TATGTGCCCT GCCCCTTCTT CCTAATCTGG 780
TGACATGCTA ACTGTGTGAC CACCAGGCCC CAGGCAGCAG CAGCTGTCAC TGGAACTGGC 840
CCTCCTCTGG ATCCTTTTCA TCCATTTTTA GGGAACAAGG ATGTCTGGAG AGACTCAGAG 900
GTTTTCAGGT CTTAGAACAG GCGTGTGTGT GTGTGTGTGT GTGTGTGTGA GAGAGAGAGA 960
GAGAGAGAGA CAATGGCAGG AACTCAGACC CTAGGAAGGC ACAAAGTCCT GGGGGCTCCA 1020
ACTTCCTGAA GGATGCATTG GTTTTGATAG CCTGGGCTGC CATCCTCTGC CACCTTCCCT 1080