| Tag | Content |
|---|
EnhancerAtlas ID | HS002-05368 |
Organism | Homo sapiens |
Tissue/cell | A375 |
Coordinate | chr2:85730370-85733380 |
Target genes | |
TF binding sites/motifs | | TF | JASPAR ID | Coordinate | Motif Sequence | Strand | -Log10(p-value) |
| ESR1 | MA0112.3 | chr2:85731310-85731327 | GAGGTCACAGTGCCCTT | - | 6.11 | | ESR1 | MA0112.3 | chr2:85731310-85731327 | GAGGTCACAGTGCCCTT | + | 6.39 | | ESR2 | MA0258.2 | chr2:85731311-85731326 | AGGTCACAGTGCCCT | + | 7.39 | | EWSR1-FLI1 | MA0149.1 | chr2:85732233-85732251 | GGAAGGGAGGCAGGAAGC | + | 7.65 | | IRF1 | MA0050.2 | chr2:85732553-85732574 | AAGAAGAAAAAGAAAGAAAAA | - | 6.42 | | IRF1 | MA0050.2 | chr2:85732559-85732580 | AAAAAGAAAGAAAAAGAAAAA | - | 6.68 | | RREB1 | MA0073.1 | chr2:85731829-85731849 | CCCCTCCCCACCCCCCACCA | + | 6.83 | | ZNF263 | MA0528.1 | chr2:85732800-85732821 | TTCCCTTCCACCTCCTGCTCT | - | 6.35 |
|
| | Number of super-enhancer constituents: 10 | ID | Coordinate | Tissue/cell |
| SE_27222 | chr2:85730155-85733634 | Esophagus | | SE_34228 | chr2:85729832-85733745 | HCC1954 | | SE_41172 | chr2:85729791-85733735 | Left_Ventricle | | SE_42782 | chr2:85731728-85733328 | Lung | | SE_47246 | chr2:85729341-85735295 | Panc1 | | SE_50398 | chr2:85729771-85733720 | Sigmoid_Colon | | SE_51553 | chr2:85730417-85735096 | Skeletal_Muscle | | SE_52637 | chr2:85729406-85733704 | Small_Intestine | | SE_65897 | chr2:85730254-85732146 | Pancreatic_islets | | SE_65897 | chr2:85732316-85733695 | Pancreatic_islets |
|
| | Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder | | Number of disease enhancers: 2 | Chromosome | Start | End |
| chr2 | 85733158 | 85733262 | | chr2 | 85732593 | 85732995 |
|
| | Number: 1 | ID | Chromosome | Start | End |
| GH02I085502 | chr2 | 85729406 | 85735140 |
|
Enhancer Sequence | CTGCACCCCC TTGGGGGACT AACAGGGAGC ACACAGATGA GGACCACAGC CAGAGCCAGA 60
GCCAGAGTCC AAGTCCATCT TGACAACTCA GAGAAGACTT TGGCCCTTGC TTCTGGCTCT 120
GTCCACGCCC TTCGTAGCAC CCACGGAGCA GAGGGGCCTG GTCACAGGGA GAGGCTGAGA 180
TGCCCAGAGA AATGGATCTG GCCACCTGAG CTGAGGCTTC TCTGAAGGTG AGTCTTCACC 240
GACCCCGCCC TAGTAGTGGT GAATCGCGTG TCCTGCCCTG TTCTCTGCTG CCCCTGAGCA 300
GTGTCTGAAC CAGGGGCGCC TTTTAACGCC ACAGATTCTG CCTCAGGGCG TGGAACACCT 360
TCTTCTAGAG GGGCGCGTGA GAACTCTGGT AGGCAGGAGC TTGCTCTGAA ACTACTGTGC 420
TAGTCAACCA ATTGCCTCAG CTGGCCACCC AGGGCCTGGC ATCCACACTG GTCCCTGGCA 480
AGCCGTTCTG CACAGAGGTT TTCACACACG TGGGTACGGA GCACTGGCAG GAAGTACGAG 540
ACATTAGAAA TTAGAAGCCC AAGCTAATAA CACAGATCAC CATCGGGGCT TCACTTTTTG 600
CCAGCCACTT CTACGTAAAT ATATCTGGTT CTACCCTTCA CTCAGCCAAG GCATGGGCGC 660
TACTGGCCTC TGACTCAGCG CTCTTCATTG GCCTCAGCTG TTAAACTTGC TCCCTTCTGA 720
TATTTTGCAG ATGCTAAGCA CTCAACTGGT TTGTTGTGGC TTTGCATCGT GCTCTTTCTC 780
ATAATCCTGA GATGAGAGGC CACTATGTCC TCTGGGTCTG CGGGACTTCT GGGGCAAGGG 840
TGCGGGGCAG GCCCAGCACA GGTGTCCAGG GAGCTGCCCA CACTGCCGCT GTGTGCTCTT 900
GGGAGTCCTG TTGGCTGTTC CATTCTCCTC TCTGCCCACA GAGGTCACAG TGCCCTTGCG 960
AGTAAGCAGG AGAAGGCAGA GTCATGAATT AGCAACTGGA AAGGATAAAT GCCAAAGGCC 1020
TTGCTATGAA ATCGAGGACC CCGCACCAGC TGCCCCGAGG TCCCTCTGGC TCATTTCCTC 1080
CTGTTCTCTC CTCACGTCAC TCCTCATTTT TCCTGGAACA TGCCAGGCCC ACTCCTGCCC 1140
CAGGGCCTTT GCATCACATG CCATCCAGAT AACCTGGTGC TCCCTTCCGG ATTCCTGCTT 1200
AGCTTTTTGT TCTAATGTCT TTTTTCTTTT TATTTTTTAT TTTTATTTTT TTGAATCGTG 1260
GTCTTGCTTT GTCACCCAAG CGAGGCTGCA GTGGTGTGAT CATGGCTCAC TGTGGCTTTG 1320
AATTCCTGAC CTCAAGTGAT CCTCCAGCCT TAGCCTACCA AAAGCTGGGA TTACAGGCAT 1380
ATGCCACGGT GCCCAGCCCT AATGTTACTT ACTCATTGAG GCCTTCCTTA GCTGCTGTCT 1440
CTACAATTGC AAGCCCCCAC CCCTCCCCAC CCCCCACCAT CTGCTTTTTC CTTGGTGCCT 1500
CTCACCGTCT ATCTTATCTC GTTAATGTTT GGTCTCCCCA CCTCAGTGTT TTCATCTGTT 1560
TGCCTGCTGC TGCATCACCA GCACTGCAAC AGTGCCTGAC ACATAGCATG TGCTCAGTGA 1620
TATCTGTTAT ATGCATGAAT GAGTGGGGCT GGACTGTGAG CTGATGAGGT TCTTGCCATG 1680
GCTAACTCCA GGCAGTCATG TCATTTGGCC CAGTTCCACT CCCTTCTGGG CCTGACTCAA 1740
TTCATCTGGG TAATGAGGAG GGCACAGGAG CTGCTGCGTA AGCTGCCCTC CAGCAGTAAT 1800
AATTGATGAG TCCAGGCAGT ATCCACTTAC CACGCCAAAG AGGTCCAAGC AGCAGGCAAC 1860
AGGGGAAGGG AGGCAGGAAG CAGCTGCCAG GATGACTAAT TGGGATCTCA TGTCATTGGC 1920
TCCACGTGCC AATCCTTACA GACCTCAGCA AAGCTCAGGA CTATTAGCTC CTGAGACTCA 1980
TGCAGTCTCC TGGTCTGACC TGTCCCTCAG TGACACTCGA AAAATAACTC AGCCAGGCGT 2040
GATGGCACAC GTCTCTATTT CCAGTTACTT GGGAGGCTGA GGTGGGAAGA TCACTTATGC 2100
CCAGGAGGTT GAGGCTGCAG TGAGCCCTGA TCACTCTGCT GCATTCCAGC CTGGGCAACA 2160
GAGCAAGATT CTGACTCAAA AAAAAGAAGA AAAAGAAAGA AAAAGAAAAA ATAACTAATA 2220
ACTTCATCTT ACAGTGGTGA CACGGAGACC TGGAGCAGGA ATACAGAGAT GTGCCAAACT 2280
TTGTACAGAA ATTTTGCAAA ACTAGATTCA GCTCTCATTC CACAAATACC AGGACCTCCC 2340
CTGCACCAGG CACTGTTCTA GGCAAGGACA GAGCAATGAA GAGGGGAAGC TCCTCACCTG 2400
TGTTTCCTCG TGAGGCCTGA AGCGCCTGCT TTCCCTTCCA CCTCCTGCTC TCCAGCCTCT 2460
TAAGTCCCCT CACTCTGTGG TCAATCTAAT TGGATAGAAC CCTTTCATCT CAAAACCAAA 2520
ACAACAGCGA CCCATGCACA CTCCTAGTAG ACCAATGGGA CTGTAGCACT GATTTCACCA 2580
TATGCCCCTC CTGCATCCCA GGGACGTCAA CTCTGCACTT CAGTCCAGCT TTCAGGAAAC 2640
TCCAAATCTC TCCCCCATTC CCACCTCTTC CTGTCTATGG TCCCACTGTG AGCCGATAGA 2700
GTTCTCACCA CGGCTGACAC CAGGCAGCCA TGTGGTTGGG GCCAGTCCCA TTCCCTTCTG 2760
GGCCTGATTC AGTTCATCTG GCTAATGAGG AGGGCACATG AGCCTTCTGT GCCTGTTGGG 2820
CCGGCTGCCT CAGTGACCAC TGCCAATTGT GTGTTCCCCT TATTCAGCAC CTTCATACCT 2880
TCTTCCGGTT TTGCCCATCT GAGCTGAATC AATTCCTCCA TCTTCACAGG GAGGTAGCCT 2940
TCTCTCAGTC CCCAAACCCT TGATAAGGGA ACGCACCACC ACCTCGCAGG CCTGCCTGAC 3000
TTGAGTGCAT 3010
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